Positive Control: HeLa, HeLa nuclear extract
Predicted Reactivity: Mouse (81%), Rat (80%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
ARID5B encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. ARID5B also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARID domain-containing protein 5B; AT rich interactive domain 5B (MRF1-like); AT-rich interactive domain 5B (MRF1-like); AT-rich interactive domain-containing protein 5B; DESRT; Modulator recognition factor 2; modulator recognition factor 2 (MRF2); MRF-2; MRF1-like protein; MRF2
Gene Aliases: ARID5B; DESRT; MRF-2; MRF2
UniProt ID: (Human) Q14865
Entrez Gene ID: (Human) 84159