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Proteintech
ARL13B Polyclonal Antibody
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FIGURE: 1 / 20
ARL13B Antibody (17711-1-AP) in ICC/IF
Immunofluorescent images of MDCK cells stained with ARL13B rabbit pAb (17711-1-AP) and acetylated tubulin mouse mAb (66200-1-Ig) at dilution of 1:50, further stained with Alexa Fluor 488-conjugated AffiniPure-Goat anti-Rabbit IgG (H+L) for 17711-1-AP, and Alexa Fluor 594-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L) for 66200-1-Ig.
Product Details
17711-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Published species
Chicken,
Dog,
Human,
Mouse,
Pig,
Rat,
Sheep,
Xenopus,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARL13B Fusion Protein Ag12015 (1-321 aa encoded by BC094725)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody detects two specific bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia.
Immunogen sequence: MFSLMASCC GWFKRWREPV RLANKQDKEG ALGEADVIEC LSLEKLVNEH KCLCQIEPCS AISGYGKKID KSIKKGLYWL LHVIARDFDA LNERIQKETT EQRALEEQEK QERAERVRKL REERKQNEQE QAELDGTSGL AELDPEPTNP FQPIASVIIE NEGKLEREKK NQKMEKDSDG CHLKHKMEHE QIETQGQVNH NGQKNNEFGL VENYKEALTQ QLKNEDETDR PSLESANGKK KTKKLRMKRN HRVEPLNIDD CAPESPTPPP PPPPVGWGTP KVTRLPKLEP LGETHHNDFY RKPLPPLAVP QRPNSDAHDV IS (1-321 aa encoded by BC094725)
Target Information
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP ribosylation factor like GTPase 13B; ADP-ribosylation factor-like 2-like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein hennin; unnamed protein product
Gene Aliases: A530097K21Rik; A930014M17Rik; ARL13B; ARL2L1; C530009C10Rik; hnn; JBTS8
UniProt ID: (Human) Q3SXY8, (Mouse) Q640N2
Entrez Gene ID: (Dog) 487934, (Human) 200894, (Rat) 304037, (Mouse) 68146
heart looping
smoothened signaling pathway
determination of left/right symmetry
dorsal/ventral pattern formation
neural tube patterning
interneuron migration from the subpallium to the cortex
formation of radial glial scaffolds
cilium morphogenesis
left/right axis specification
receptor localization to nonmotile primary cilium
non-motile cilium assembly
small GTPase mediated signal transduction
nonmotile primary cilium assembly
cilium assembly
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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