Product References
Primary Cilium Identifies a Quiescent Cell Population in the Human Intestinal Crypt.
Cells
Sénicourt B,Cloutier G,Basora N,Fallah S,Laniel A,Lavoie C,Beaulieu JF
Fri Mar 31 00:00:00 EDT 2023
The developmental basis of fingerprint pattern formation and variation.
Cell
Glover JD,Sudderick ZR,Shih BB,Batho-Samblas C,Charlton L,Krause AL,Anderson C,Riddell J,Balic A,Li J,Klika V,Woolley TE,Gaffney EA,Corsinotti A,Anderson RA,Johnston LJ,Brown SJ,Wang S,Chen Y,Crichton ML,Headon DJ
Thu Mar 02 00:00:00 EST 2023
Impairment of Connexin 43 may initiate cilia decline in syringomyelia.
Experimental neurology
Wang X,Jiang C,Lu C,Ma L,Feng Y,Cui S,Li Q,Li K,Wang X,Jian F
Sat Jul 01 00:00:00 EDT 2023
PDGF-AA activates AKT and ERK signaling for testicular interstitial Leydig cell growth via primary cilia.
Journal of cellular biochemistry
Tsai YC,Kuo TN,Chao YY,Lee PR,Lin RC,Xiao XY,Huang BM,Wang CY
Sun Jan 01 00:00:00 EST 2023
Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence.
The Journal of biological chemistry
Mahajan D,Madugula V,Lu L
Mon May 01 00:00:00 EDT 2023
Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence.
The Journal of biological chemistry
Mahajan D,Madugula V,Lu L
Mon May 01 00:00:00 EDT 2023
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective intraflagellar transport.
Journal of cell science
Hiyamizu S,Qiu H,Vuolo L,Stevenson NL,Shak C,Heesom KJ,Hamada Y,Tsurumi Y,Chiba S,Katoh Y,Stephens DJ,Nakayama K
Wed Mar 01 00:00:00 EST 2023
Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition.
Communications biology
Portal C,Lin Y,Rastogi V,Peterson C,Yiu SC,Foster JW,Wilkerson A,Butovich IA,Iomini C
Fri Mar 17 00:00:00 EDT 2023
MRCKα/β positively regulates Gli protein activity.
Cellular signalling
Baran B,Kosieradzka K,Skarzynska W,Niewiadomski P
Sat Jul 01 00:00:00 EDT 2023
Human LUHMES and NES cells as models for studying primary cilia in neurons.
Methods in cell biology
Coschiera A,Watts ME,Kere J,Tammimies K,Swoboda P
Fri May 12 00:00:00 EDT 2023
Kif6 regulates cilia motility and polarity in brain ependymal cells.
bioRxiv : the preprint server for biology
Takagishi M,Yue Y,Gray RS,Verhey KJ,Wallingford JB
Thu Feb 16 00:00:00 EST 2023
CEP164-GLI2 association ensures the hedgehog signaling in pancreatic cancer cells.
Biochemical and biophysical research communications
Fushimi T,Kobayashi T,Itoh H
Sun Jul 23 00:00:00 EDT 2023
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.
Development (Cambridge, England)
Elliott KH,Balchand SK,Bonatto Paese CL,Chang CF,Yang Y,Brown KM,Rasicci DT,He H,Thorner K,Chaturvedi P,Murray SA,Chen J,Porollo A,Peterson KA,Brugmann SA
Sat Apr 15 00:00:00 EDT 2023
A stress-induced cilium-to-PML-NB route drives senescence initiation.
Nature communications
Ma X,Zhang Y,Zhang Y,Zhang X,Huang Y,He K,Chen C,Hao J,Zhao D,LeBrasseur NK,Kirkland JL,Chini EN,Wei Q,Ling K,Hu J
Mon Apr 03 00:00:00 EDT 2023
A stress-induced cilium-to-PML-NB route drives senescence initiation.
Nature communications
Ma X,Zhang Y,Zhang Y,Zhang X,Huang Y,He K,Chen C,Hao J,Zhao D,LeBrasseur NK,Kirkland JL,Chini EN,Wei Q,Ling K,Hu J
Mon Apr 03 00:00:00 EDT 2023
LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
Cell and tissue research
Bunatyan L,Margineanu A,Boutin C,Montcouquiol M,Bachmann S,Ilsø Christensen E,Willnow TE,Christ A
Mon May 01 00:00:00 EDT 2023
Arl13b promotes the proliferation, migration, osteogenesis, and mechanosensation of osteoblasts.
Tissue & cell
Lin T,Sun Y
Thu Jun 01 00:00:00 EDT 2023
Arl13b promotes the proliferation, migration, osteogenesis, and mechanosensation of osteoblasts.
Tissue & cell
Lin T,Sun Y
Thu Jun 01 00:00:00 EDT 2023
Scanning electron microscopy of human islet cilia.
bioRxiv : the preprint server for biology
Polino AJ,Sviben S,Melena I,Piston DW,Hughes J
Wed Feb 15 00:00:00 EST 2023
Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.
Developmental cell
Feng X,Wang AH,Juan AH,Ko KD,Jiang K,Riparini G,Ciuffoli V,Kaba A,Lopez C,Naz F,Jarnik M,Aliberti E,Hu S,Segalés J,Khateb M,Acevedo-Luna N,Randazzo D,Cheung TH,Muñoz-Cánoves P,Dell'Orso S,Sartorelli V
Mon Jun 19 00:00:00 EDT 2023
Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse.
Developmental biology
Van Sciver RE,Long AB,Katz HG,Gigante ED,Caspary T
Tue Aug 01 00:00:00 EDT 2023
Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain.
PLoS genetics
Washington-Hughes CL,Roy S,Seneviratne HK,Karuppagounder SS,Morel Y,Jones JW,Zak A,Xiao T,Boronina TN,Cole RN,Bumpus NN,Chang CJ,Dawson TM,Lutsenko S
Sun Jan 01 00:00:00 EST 2023
Evaluation of Epithelial-Mesenchymal Transition Markers in Autoimmune Thyroid Diseases.
International journal of molecular sciences
Sacristán-Gómez P,Serrano-Somavilla A,Castro-Espadas L,Sánchez de la Blanca Carrero N,Sampedro-Núñez M,Muñoz-De-Nova JL,Molina-Jiménez F,Rosell A,Marazuela M,Martínez-Hernández R
Wed Feb 08 00:00:00 EST 2023
Evaluation of Epithelial-Mesenchymal Transition Markers in Autoimmune Thyroid Diseases.
International journal of molecular sciences
Sacristán-Gómez P,Serrano-Somavilla A,Castro-Espadas L,Sánchez de la Blanca Carrero N,Sampedro-Núñez M,Muñoz-De-Nova JL,Molina-Jiménez F,Rosell A,Marazuela M,Martínez-Hernández R
Wed Feb 08 00:00:00 EST 2023
CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.
Neuron
Van Heurck R,Bonnefont J,Wojno M,Suzuki IK,Velez-Bravo FD,Erkol E,Nguyen DT,Herpoel A,Bilheu A,Beckers S,Ledent C,Vanderhaeghen P
Wed Jan 04 00:00:00 EST 2023
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
The Journal of clinical investigation
Lee D,Gimple RC,Wu X,Prager BC,Qiu Z,Wu Q,Daggubati V,Mariappan A,Gopalakrishnan J,Sarkisian MR,Raleigh DR,Rich JN
Tue Jan 17 00:00:00 EST 2023
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
The Journal of clinical investigation
Lee D,Gimple RC,Wu X,Prager BC,Qiu Z,Wu Q,Daggubati V,Mariappan A,Gopalakrishnan J,Sarkisian MR,Raleigh DR,Rich JN
Tue Jan 17 00:00:00 EST 2023
A SEC61A1 variant is associated with autosomal dominant polycystic liver disease.
Liver international : official journal of the International Association for the Study of the Liver
Schlevogt B,Schlieper V,Krader J,Schröter R,Wagner T,Weiand M,Zibert A,Schmidt HH,Bergmann C,Nedvetsky PI,Krahn MP
Wed Feb 01 00:00:00 EST 2023
An actin filament branching surveillance system regulates cell cycle progression, cytokinesis and primary ciliogenesis.
Nature communications
Cao M,Zou X,Li C,Lin Z,Wang N,Zou Z,Ye Y,Seemann J,Levine B,Tang Z,Zhong Q
Mon Mar 27 00:00:00 EDT 2023
Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse.
bioRxiv : the preprint server for biology
Van Sciver RE,Long AB,Katz HG,Gigante ED,Caspary T
Mon May 15 00:00:00 EDT 2023
Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages.
bioRxiv : the preprint server for biology
Kanie T,Ng R,Abbott KL,Pongs O,Jackson PK
Tue Jan 10 00:00:00 EST 2023
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins.
bioRxiv : the preprint server for biology
Muñoz-Estrada J,Nguyen AV,Goetz SC
Wed Feb 01 00:00:00 EST 2023
Increase in primary cilia number and length upon VDAC1 depletion contributes to attenuated proliferation of cancer cells.
Experimental cell research
Dutta A,Halder P,Gayen A,Mukherjee A,Mukherjee C,Majumder S
Tue Aug 15 00:00:00 EDT 2023
Ubiquitylation of BBSome is required for ciliary assembly and signaling.
EMBO reports
Chiuso F,Delle Donne R,Giamundo G,Rinaldi L,Borzacchiello D,Moraca F,Intartaglia D,Iannucci R,Senatore E,Lignitto L,Garbi C,Conflitti P,Catalanotti B,Conte I,Feliciello A
Wed Apr 05 00:00:00 EDT 2023
Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia.
Nature protocols
Gabriel E,Albanna W,Pasquini G,Ramani A,Josipovic N,Mariappan A,Riparbelli MG,Callaini G,Karch CM,Goureau O,Papantonis A,Busskamp V,Schneider T,Gopalakrishnan J
Thu Jun 01 00:00:00 EDT 2023
Primary cilia sense glutamine availability and respond via asparagine synthetase.
Nature metabolism
Steidl ME,Nigro EA,Nielsen AK,Pagliarini R,Cassina L,Lampis M,Podrini C,Chiaravalli M,Mannella V,Distefano G,Yang M,Aslanyan M,Musco G,Roepman R,Frezza C,Boletta A
Wed Mar 01 00:00:00 EST 2023
Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases.
Life science alliance
Gregorczyk M,Pastore G,Muñoz I,Carroll T,Streubel J,Munro M,Lis P,Lange S,Lamoliatte F,Macartney T,Toth R,Brown F,Hastie J,Pereira G,Durocher D,Rouse J
Sat Jul 01 00:00:00 EDT 2023
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
eLife
Li Y,Xu W,Makova S,Brueckner M,Sun Z
Wed Mar 15 00:00:00 EDT 2023
TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins.
Molecular biology of the cell
Nguyen A,Goetz SC
Sun Jan 01 00:00:00 EST 2023
Enhanced primary ciliogenesis via mitochondrial oxidative stress activates AKT to prevent neurotoxicity in HSPA9/mortalin-depleted SH-SY5Y cells.
Molecular brain
Bae JE,Jang S,Kim JB,Hyung H,Park NY,Kim YH,Kim SH,Kim SH,Ha JM,Oh GS,Park K,Jeong K,Jang JS,Jo DS,Kim P,Lee HS,Ryoo ZY,Cho DH
Thu May 11 00:00:00 EDT 2023
Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids.
Stem cells international
Ning K,Luo Z,Kowal TJ,Tran M,Majumder R,Jarin TM,Wu AY,Goldberg JL,Sun Y
Wed Feb 22 00:00:00 EST 2023
A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome.
Frontiers in cell and developmental biology
Aslanyan MG,Doornbos C,Diwan GD,Anvarian Z,Beyer T,Junger K,van Beersum SEC,Russell RB,Ueffing M,Ludwig A,Boldt K,Pedersen LB,Roepman R
Tue Feb 14 00:00:00 EST 2023
XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice.
Journal of the American Society of Nephrology : JASN
Krappitz M,Bhardwaj R,Dong K,Staudner T,Yilmaz DE,Pioppini C,Westergerling P,Ruemmele D,Hollmann T,Nguyen TA,Cai Y,Gallagher AR,Somlo S,Fedeles S
Sun Jan 01 00:00:00 EST 2023
A hierarchical pathway for assembly of the distal appendages that organize primary cilia.
bioRxiv : the preprint server for biology
Kanie T,Love JF,Fisher SD,Gustavsson AK,Jackson PK
Tue Jan 10 00:00:00 EST 2023
Investigations on Primary Cilia of Nthy-ori 3-1 Cells upon Cysteine Cathepsin Inhibition or Thyrotropin Stimulation.
International journal of molecular sciences
Doğru AG,Rehders M,Brix K
Fri May 26 00:00:00 EDT 2023
Eupatilin improves cilia defects in human CEP290 ciliopathy models.
bioRxiv : the preprint server for biology
Corral-Serrano JC,Sladen PE,Ottaviani D,Rezek FO,Jovanovic K,Athanasiou D,van der Spuy J,Mansfield BC,Cheetham ME
Wed Apr 12 00:00:00 EDT 2023
WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium.
Life science alliance
Cevik S,Peng X,Beyer T,Pir MS,Yenisert F,Woerz F,Hoffmann F,Altunkaynak B,Pir B,Boldt K,Karaman A,Cakiroglu M,Oner SS,Cao Y,Ueffing M,Kaplan OI
Tue Aug 01 00:00:00 EDT 2023
IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice.
Science signaling
Li B,Yan YP,He YY,Liang C,Li MY,Wang Y,Yang ZM
Tue Feb 28 00:00:00 EST 2023
IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice.
Science signaling
Li B,Yan YP,He YY,Liang C,Li MY,Wang Y,Yang ZM
Tue Feb 28 00:00:00 EST 2023
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
eLife
Hall EA,Kumar D,Prosser SL,Yeyati PL,Herranz-Pérez V,García-Verdugo JM,Rose L,McKie L,Dodd DO,Tennant PA,Megaw R,Murphy LC,Ferreira MF,Grimes G,Williams L,Quidwai T,Pelletier L,Reiter JF,Mill P
Wed Feb 15 00:00:00 EST 2023
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression.
EMBO reports
Appiah B,Fullio CL,Ossola C,Bertani I,Restelli E,Cheffer A,Polenghi M,Haffner C,Garcia-Miralles M,Zeis P,Treppner M,Bovio P,Schlichtholz L,Mas-Sanchez A,Zografidou L,Winter J,Binder H,Grün D,Kalebic N,Taverna E,Vogel T
Thu Aug 03 00:00:00 EDT 2023
Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.
Developmental cell
Zhang K,Da Silva F,Seidl C,Wilsch-Bräuninger M,Herbst J,Huttner WB,Niehrs C
Mon Jan 23 00:00:00 EST 2023
Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.
Developmental cell
Zhang K,Da Silva F,Seidl C,Wilsch-Bräuninger M,Herbst J,Huttner WB,Niehrs C
Mon Jan 23 00:00:00 EST 2023
Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.
Developmental cell
Zhang K,Da Silva F,Seidl C,Wilsch-Bräuninger M,Herbst J,Huttner WB,Niehrs C
Mon Jan 23 00:00:00 EST 2023
Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.
Developmental cell
Zhang K,Da Silva F,Seidl C,Wilsch-Bräuninger M,Herbst J,Huttner WB,Niehrs C
Mon Jan 23 00:00:00 EST 2023
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia.
Molecular biology of the cell
Palicharla VR,Hwang SH,Somatilaka BN,Legué E,Shimada IS,Familiari NE,Tran VM,Woodruff JB,Liem KF,Mukhopadhyay S
Wed Mar 01 00:00:00 EST 2023
Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brain.
Molecular therapy : the journal of the American Society of Gene Therapy
Ma R,Kutchy NA,Wang Z,Hu G
Wed May 03 00:00:00 EDT 2023
Scanning electron microscopy of human islet cilia.
Proceedings of the National Academy of Sciences of the United States of America
Polino AJ,Sviben S,Melena I,Piston DW,Hughes JW
Tue May 30 00:00:00 EDT 2023
Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish.
Proceedings of the National Academy of Sciences of the United States of America
Khatri D,Putoux A,Cologne A,Kaltenbach S,Besson A,Bertiaux E,Guguin J,Fendler A,Dupont MA,Benoit-Pilven C,Qebibo L,Ahmed-Elie S,Audebert-Bellanger S,Blanc P,Rambaud T,Castelle M,Cornen G,Grotto S,Guët A,Guibaud L,Michot C,Odent S,Ruaud L,Sacaze E,Hamel V,Bordonné R,Leutenegger AL,Edery P,Burglen L,Attié-Bitach T,Mazoyer S,Delous M
Tue Feb 28 00:00:00 EST 2023
CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis.
BMC biology
Wang Y,Zhang Y,Guo X,Zheng Y,Zhang X,Feng S,Wu HY
Wed May 24 00:00:00 EDT 2023
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
Cell death and differentiation
Zhang J,Yang Y,Li X,Li G,Mizukami T,Liu Y,Wang Y,Xu G,Roder H,Zhang L,Yang ZJ
Mon May 01 00:00:00 EDT 2023
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
Cell death and differentiation
Zhang J,Yang Y,Li X,Li G,Mizukami T,Liu Y,Wang Y,Xu G,Roder H,Zhang L,Yang ZJ
Mon May 01 00:00:00 EDT 2023
Morphological changes and two Nodal paralogs drive left-right asymmetry in the squamate veiled chameleon (C. calyptratus).
Frontiers in cell and developmental biology
Shylo NA,Smith SE,Price AJ,Guo F,McClain M,Trainor PA
Sun Apr 30 00:00:00 EDT 2023
Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Communications biology
Freitag K,Eede P,Ivanov A,Sterczyk N,Schneeberger S,Borodina T,Sauer S,Beule D,Heppner FL
Fri Jan 13 00:00:00 EST 2023
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
The Journal of biological chemistry
Iwano T,Sobajima T,Takeda S,Harada A,Yoshimura SI
Wed Mar 01 00:00:00 EST 2023
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
The Journal of biological chemistry
Iwano T,Sobajima T,Takeda S,Harada A,Yoshimura SI
Wed Mar 01 00:00:00 EST 2023
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
Journal of cell science
Shak C,Vuolo L,Uddin B,Katoh Y,Brown T,Mukhopadhyay AG,Heesom K,Roberts AJ,Stevenson N,Nakayama K,Stephens DJ
Wed Mar 01 00:00:00 EST 2023
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
Journal of cell science
Shak C,Vuolo L,Uddin B,Katoh Y,Brown T,Mukhopadhyay AG,Heesom K,Roberts AJ,Stevenson N,Nakayama K,Stephens DJ
Wed Mar 01 00:00:00 EST 2023
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects.
eLife
Chen HY,Swaroop M,Papal S,Mondal AK,Song HB,Campello L,Tawa GJ,Regent F,Shimada H,Nagashima K,de Val N,Jacobson SG,Zheng W,Swaroop A
Tue Mar 28 00:00:00 EDT 2023
Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis.
Development (Cambridge, England)
Janečková E,Feng J,Guo T,Han X,Ghobadi A,Araujo-Villalba A,Rahman MS,Ziaei H,Ho TV,Pareek S,Alvarez J,Chai Y
Wed Mar 01 00:00:00 EST 2023
Agonists of prostaglandin E2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies.
Proceedings of the National Academy of Sciences of the United States of America
Garcia H,Serafin AS,Silbermann F,Porée E,Viau A,Mahaut C,Billot K,Birgy É,Garfa-Traore M,Roy S,Ceccarelli S,Mehraz M,Rodriguez PC,Deleglise B,Furio L,Jabot-Hanin F,Cagnard N,Del Nery E,Fila M,Sin-Monnot S,Antignac C,Lyonnet S,Krug P,Salomon R,Annereau JP,Benmerah A,Delous M,Briseño-Roa L,Saunier S
Tue May 03 00:00:00 EDT 2022
Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure (London, England : 1993)
Rosa E Silva I,Binó L,Johnson CM,Rutherford TJ,Neuhaus D,Andreeva A,Čajánek L,van Breugel M
Thu Jan 06 00:00:00 EST 2022
Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus.
Frontiers in cellular and infection microbiology
Ekanger CT,Zhou F,Bohan D,Lotsberg ML,Ramnefjell M,Hoareau L,Røsland GV,Lu N,Aanerud M,Gärtner F,Salminen PR,Bentsen M,Halvorsen T,Ræder H,Akslen LA,Langeland N,Cox R,Maury W,Stuhr LEB,Lorens JB,Engelsen AST
Tue Apr 05 00:00:00 EDT 2022
Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism.
Cell death & disease
Ávalos Y,Hernández-Cáceres MP,Lagos P,Pinto-Nuñez D,Rivera P,Burgos P,Díaz-Castro F,Joy-Immediato M,Venegas-Zamora L,Lopez-Gallardo E,Kretschmar C,Batista-Gonzalez A,Cifuentes-Araneda F,Toledo-Valenzuela L,Rodriguez-Peña M,Espinoza-Caicedo J,Perez-Leighton C,Bertocchi C,Cerda M,Troncoso R,Parra V,Budini M,Burgos PV,Criollo A,Morselli E
Thu Jul 28 00:00:00 EDT 2022
Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism.
Cell death & disease
Ávalos Y,Hernández-Cáceres MP,Lagos P,Pinto-Nuñez D,Rivera P,Burgos P,Díaz-Castro F,Joy-Immediato M,Venegas-Zamora L,Lopez-Gallardo E,Kretschmar C,Batista-Gonzalez A,Cifuentes-Araneda F,Toledo-Valenzuela L,Rodriguez-Peña M,Espinoza-Caicedo J,Perez-Leighton C,Bertocchi C,Cerda M,Troncoso R,Parra V,Budini M,Burgos PV,Criollo A,Morselli E
Thu Jul 28 00:00:00 EDT 2022
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Nature communications
Schmidt S,Luecken MD,Trümbach D,Hembach S,Niedermeier KM,Wenck N,Pflügler K,Stautner C,Böttcher A,Lickert H,Ramirez-Suastegui C,Ahmad R,Ziller MJ,Fitzgerald JC,Ruf V,van de Berg WDJ,Jonker AJ,Gasser T,Winner B,Winkler J,Vogt Weisenhorn DM,Giesert F,Theis FJ,Wurst W
Tue Aug 16 00:00:00 EDT 2022
Biallelic KIF24 Variants Are Responsible for a Spectrum of Skeletal Disorders Ranging From Lethal Skeletal Ciliopathy to Severe Acromesomelic Dysplasia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Reilly ML,Ain NU,Muurinen M,Tata A,Huber C,Simon M,Ishaq T,Shaw N,Rusanen S,Pekkinen M,Högler W,Knapen MFCM,van den Born M,Saunier S,Naz S,Cormier-Daire V,Benmerah A,Makitie O
Thu Sep 01 00:00:00 EDT 2022
Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein.
Frontiers in cell and developmental biology
An HL,Kuo HC,Tang TK
Tue Mar 22 00:00:00 EDT 2022
Precise control of microtubule disassembly in living cells.
The EMBO journal
Liu GY,Chen SC,Lee GH,Shaiv K,Chen PY,Cheng H,Hong SR,Yang WT,Huang SH,Chang YC,Wang HC,Kao CL,Sun PC,Chao MH,Lee YY,Tang MJ,Lin YC
Mon Aug 01 00:00:00 EDT 2022
ATM- and ATR-induced primary ciliogenesis promotes cisplatin resistance in pancreatic ductal adenocarcinoma.
Journal of cellular physiology
Chao YY,Huang BM,Peng IC,Lee PR,Lai YS,Chiu WT,Lin YS,Lin SC,Chang JH,Chen PS,Tsai SJ,Wang CY
Thu Dec 01 00:00:00 EST 2022
Analysis of Primary Cilium Expression and Hedgehog Pathway Activation in Mesothelioma Throws Back Its Complex Biology.
Cancers
Barbarino M,Bottaro M,Spagnoletti L,de Santi MM,Guazzo R,Defraia C,Custoza C,Serio G,Iannelli F,Pesetti M,Aiello R,Rosati D,Zanfrini E,Luzzi L,Bellan C,Giordano A
Tue Oct 25 00:00:00 EDT 2022
Analysis of Primary Cilium Expression and Hedgehog Pathway Activation in Mesothelioma Throws Back Its Complex Biology.
Cancers
Barbarino M,Bottaro M,Spagnoletti L,de Santi MM,Guazzo R,Defraia C,Custoza C,Serio G,Iannelli F,Pesetti M,Aiello R,Rosati D,Zanfrini E,Luzzi L,Bellan C,Giordano A
Tue Oct 25 00:00:00 EDT 2022
GLI transcriptional repression is inert prior to Hedgehog pathway activation.
Nature communications
Lex RK,Zhou W,Ji Z,Falkenstein KN,Schuler KE,Windsor KE,Kim JD,Ji H,Vokes SA
Thu Feb 10 00:00:00 EST 2022
Biallelic variants in CENPF causing a phenotype distinct from Strømme syndrome.
American journal of medical genetics. Part C, Seminars in medical genetics
Cappuccio G,Brillante S,Tammaro R,Pinelli M,De Bernardi ML,Gensini MG,Bijlsma EK,Koopmann TT,Hoffer MJV,McDonald K,Hendon LG,Douzgou S,Deshpande C,D'Arrigo S,Torella A,Nigro V,Franco B,Brunetti-Pierri N
Tue Mar 01 00:00:00 EST 2022
A protocol for generation and live-cell imaging analysis of primary cilia reporter cell lines.
STAR protocols
Binó L,Mikulenková E,Štepánek L,Bernatík O,Vysloužil D,Pejšková P,Gorilák P,Huranová M,Varga V,Čajánek L
Fri Mar 18 00:00:00 EDT 2022
Renal primary cilia lengthen in the progression of diabetic kidney disease.
Frontiers in endocrinology
Bai Y,Li P,Liu J,Zhang L,Cui S,Wei C,Fu B,Sun X,Cai G,Hong Q,Chen X
Tue Dec 06 00:00:00 EST 2022
Evolutionarily conserved genetic interactions between nphp-4 and bbs-5 mutations exacerbate ciliopathy phenotypes.
Genetics
Bentley-Ford MR,LaBonty M,Thomas HR,Haycraft CJ,Scott M,LaFayette C,Croyle MJ,Andersen RS,Parant JM,Yoder BK
Tue Jan 04 00:00:00 EST 2022
A pair of primers facing at the double-strand break site enables to detect NHEJ-mediated indel mutations at a 1-bp resolution.
Scientific reports
Ijaz F,Nakazato R,Setou M,Ikegami K
Fri Jul 08 00:00:00 EDT 2022
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
Biomedical and environmental sciences : BES
Wei L,Ma W,Cai H,Peng SP,Tian HB,Wang JF,Gao L,He JP
Fri May 20 00:00:00 EDT 2022
Islet primary cilia motility controls insulin secretion.
Science advances
Cho JH,Li ZA,Zhu L,Muegge BD,Roseman HF,Lee EY,Utterback T,Woodhams LG,Bayly PV,Hughes JW
Fri Sep 23 00:00:00 EDT 2022
Nuclear factor (erythroid-derived 2)-like 2 counter-regulates thymosin beta-4 expression and primary cilium formation for HeLa cervical cancer cell survival.
Scientific reports
Lee JW,Thuy PX,Koo JH,Moon EY
Wed Nov 23 00:00:00 EST 2022
Cilia proteins are biomarkers of altered flow in the vasculature.
JCI insight
Gupta A,Thirugnanam K,Thamilarasan M,Mohieldin AM,Zedan HT,Prabhudesai S,Griffin MR,Spearman AD,Pan A,Palecek SP,Yalcin HC,Nauli SM,Rarick KR,Zennadi R,Ramchandran R
Tue Mar 22 00:00:00 EDT 2022
Cilia proteins are biomarkers of altered flow in the vasculature.
JCI insight
Gupta A,Thirugnanam K,Thamilarasan M,Mohieldin AM,Zedan HT,Prabhudesai S,Griffin MR,Spearman AD,Pan A,Palecek SP,Yalcin HC,Nauli SM,Rarick KR,Zennadi R,Ramchandran R
Tue Mar 22 00:00:00 EDT 2022
TTC30A and TTC30B Redundancy Protects IFT Complex B Integrity and Its Pivotal Role in Ciliogenesis.
Genes
Hoffmann F,Bolz S,Junger K,Klose F,Schubert T,Woerz F,Boldt K,Ueffing M,Beyer T
Fri Jul 01 00:00:00 EDT 2022
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation.
Scientific reports
Czerny CC,Borschel A,Cai M,Otto M,Hoyer-Fender S
Mon Dec 12 00:00:00 EST 2022
IFT-A structure reveals carriages for membrane protein transport into cilia.
Cell
Hesketh SJ,Mukhopadhyay AG,Nakamura D,Toropova K,Roberts AJ
Thu Dec 22 00:00:00 EST 2022
The intraflagellar transport protein IFT52 associated with short-rib thoracic dysplasia is essential for ciliary function in osteogenic differentiation in vitro and for sensory perception in Drosophila.
Experimental cell research
Guleria VS,Parit R,Quadri N,Das R,Upadhyai P
Thu Sep 15 00:00:00 EDT 2022
The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.
Journal of cell science
Smit MJ,Martini TEI,Armandari I,Bočkaj I,Zomerman WW,de Camargo Magalhães ES,Siragna Z,Meeuwsen TGJ,Scherpen FJG,Schoots MH,Ritsema M,den Dunnen WFA,Hoving EW,Paridaen JTML,de Haan G,Guryev V,Bruggeman SWM
Wed Jun 01 00:00:00 EDT 2022
KIAA0319 influences cilia length, cell migration and mechanical cell-substrate interaction.
Scientific reports
Diaz R,Kronenberg NM,Martinelli A,Liehm P,Riches AC,Gather MC,Paracchini S
Fri Jan 14 00:00:00 EST 2022
Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E.
Molecular biology of the cell
Dewees SI,Vargová R,Hardin KR,Turn RE,Devi S,Linnert J,Wolfrum U,Caspary T,Eliáš M,Kahn RA
Fri Apr 01 00:00:00 EDT 2022
Non-cell-autonomous activation of hedgehog signaling contributes to disease progression in a mouse model of renal cystic ciliopathy.
Human molecular genetics
Hsieh CL,Jerman SJ,Sun Z
Fri Dec 16 00:00:00 EST 2022
Ciliary IFT88 Protects Coordinated Adolescent Growth Plate Ossification From Disruptive Physiological Mechanical Forces.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Coveney CR,Samvelyan HJ,Miotla-Zarebska J,Carnegie J,Chang E,Corrin CJ,Coveney T,Stott B,Parisi I,Duarte C,Vincent TL,Staines KA,Wann AK
Wed Jun 01 00:00:00 EDT 2022
Ciliary IFT88 Protects Coordinated Adolescent Growth Plate Ossification From Disruptive Physiological Mechanical Forces.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Coveney CR,Samvelyan HJ,Miotla-Zarebska J,Carnegie J,Chang E,Corrin CJ,Coveney T,Stott B,Parisi I,Duarte C,Vincent TL,Staines KA,Wann AK
Wed Jun 01 00:00:00 EDT 2022
HeLa Cervical Cancer Cells Are Maintained by Nephronophthisis 3-Associated Primary Cilium Formation via ROS-Induced ERK and HIF-1α Activation under Serum-Deprived Normoxic Condition.
International journal of molecular sciences
Lee JW,Cho JY,Thuy PX,Moon EY
Tue Nov 22 00:00:00 EST 2022
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yang D,Wu X,Wang W,Zhou Y,Wang Z
Sat Jan 01 00:00:00 EST 2022
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
Nature structural & molecular biology
Happ JT,Arveseth CD,Bruystens J,Bertinetti D,Nelson IB,Olivieri C,Zhang J,Hedeen DS,Zhu JF,Capener JL,Bröckel JW,Vu L,King CC,Ruiz-Perez VL,Ge X,Veglia G,Herberg FW,Taylor SS,Myers BR
Sat Oct 01 00:00:00 EDT 2022
A high-throughput electron tomography workflow reveals over-elongated centrioles in relapsed/refractory multiple myeloma.
Cell reports methods
Dittrich T,Köhrer S,Schorb M,Haberbosch I,Börmel M,Goldschmidt H,Pajor G,Müller-Tidow C,Raab MS,Hegenbart U,Schönland SO,Schwab Y,Krämer A
Mon Nov 21 00:00:00 EST 2022
Pyrogallol-Phloroglucinol-6, 6-Bieckol Restored Primary Cilia Length, Which Was Decreased by High-Fat Diet in Visceral Adipose Tissue, and Decreased Adipogenesis.
International journal of endocrinology
Oh S,Son M,Jang JT,Park CH,Son KH,Byun K
Sat Jul 16 00:00:00 EDT 2022
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base.
eLife
Jang DG,Kwon KY,Kweon YC,Kim BG,Myung K,Lee HS,Young Park C,Kwon T,Park TJ
Thu Aug 25 00:00:00 EDT 2022
Systematic analysis of cilia characteristics and Hedgehog signaling in five immortal cell lines.
PloS one
Gómez AE,Christman AK,Van De Weghe JC,Finn M,Doherty D
Mon Jan 02 00:00:00 EST 2023
The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis.
The Journal of biological chemistry
Tsutsumi R,Chaya T,Tsujii T,Furukawa T
Tue Mar 01 00:00:00 EST 2022
Identification of a novel variant of the ciliopathic gene FUZZY associated with craniosynostosis.
European journal of human genetics : EJHG
Barrell WB,Adel Al-Lami H,Goos JAC,Swagemakers SMA,van Dooren M,Torban E,van der Spek PJ,Mathijssen IMJ,Liu KJ
Tue Mar 01 00:00:00 EST 2022
KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency-Related Polycystic Kidney Disease.
Journal of the American Society of Nephrology : JASN
Rah G,Cha H,Kim J,Song J,Kim H,Oh YK,Ahn C,Kang M,Kim J,Yoo KH,Kim MJ,Ko HW,Ko JY,Park JH
Thu Sep 01 00:00:00 EDT 2022
Hedgehog-induced ciliary trafficking of kinesin-4 motor KIF7 requires intraflagellar transport but not KIF7's microtubule binding.
Molecular biology of the cell
Yue Y,Engelke MF,Blasius TL,Verhey KJ
Sat Jan 01 00:00:00 EST 2022
Preliminary results on a proposed histopathological assessment of predictive factors for basal cell carcinoma recurrence after primary free margin excision.
Skin health and disease
Jacquet A,Dormoy V,Lorenzato M,Durlach A
Wed Jun 01 00:00:00 EDT 2022
TMED2 binding restricts SMO to the ER and Golgi compartments.
PLoS biology
Di Minin G,Holzner M,Grison A,Dumeau CE,Chan W,Monfort A,Jerome-Majewska LA,Roelink H,Wutz A
Tue Mar 01 00:00:00 EST 2022
Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly.
Cell research
Wang L,Paudyal SC,Kang Y,Owa M,Liang FX,Spektor A,Knaut H,Sánchez I,Dynlacht BD
Tue Feb 01 00:00:00 EST 2022
Physical Exercise-Induced Astrocytic Neuroprotection and Cognitive Improvement Through Primary Cilia and Mitogen-Activated Protein Kinases Pathway in Rats With Chronic Cerebral Hypoperfusion.
Frontiers in aging neuroscience
Cao W,Lin J,Xiang W,Liu J,Wang B,Liao W,Jiang T
Sat Jul 16 00:00:00 EDT 2022
Heterogeneity of the NIH3T3 Fibroblast Cell Line.
Cells
Rahimi AM,Cai M,Hoyer-Fender S
Sun Aug 28 00:00:00 EDT 2022
Monoallelic pathogenic ALG5 variants cause atypical polycystic kidney disease and interstitial fibrosis.
American journal of human genetics
Lemoine H,Raud L,Foulquier F,Sayer JA,Lambert B,Olinger E,Lefèvre S,Knebelmann B,Harris PC,Trouvé P,Desprès A,Duneau G,Matignon M,Poyet A,Jourde-Chiche N,Guerrot D,Lemoine S,Seret G,Barroso-Gil M,Bingham C,Gilbert R,Le Meur Y,Audrézet MP,Cornec-Le Gall E
Thu Aug 04 00:00:00 EDT 2022
Mitotic Maturation Compensates for Premature Centrosome Splitting and PCM Loss in Human cep135 Knockout Cells.
Cells
Chu Z,Gruss OJ
Fri Apr 01 00:00:00 EDT 2022
Evolutionary conservation of centriole rotational asymmetry in the human centrosome.
eLife
Gaudin N,Martin Gil P,Boumendjel M,Ershov D,Pioche-Durieu C,Bouix M,Delobelle Q,Maniscalco L,Phan TBN,Heyer V,Reina-San-Martin B,Azimzadeh J
Wed Mar 23 00:00:00 EDT 2022
Differential requirements for the Eps15 homology domain proteins EHD4 and EHD2 in the regulation of mammalian ciliogenesis.
Traffic (Copenhagen, Denmark)
Jones T,Naslavsky N,Caplan S
Fri Jul 01 00:00:00 EDT 2022
Porcine choroid plexus-Riems cell line demonstrates altered polarization of transport proteins compared with the native epithelium.
American journal of physiology. Cell physiology
Hochstetler A,Hulme L,Delpire E,Schwerk C,Schroten H,Preston D,Simpson S,Blazer-Yost BL
Fri Jul 01 00:00:00 EDT 2022
Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.
Nature biomedical engineering
Cruz NM,Reddy R,McFaline-Figueroa JL,Tran C,Fu H,Freedman BS
Fri Apr 01 00:00:00 EDT 2022
Microtubule modification defects underlie cilium degeneration in cell models of retinitis pigmentosa associated with pre-mRNA splicing factor mutations.
Frontiers in genetics
Nazlamova L,Villa Vasquez SS,Lord J,Karthik V,Cheung MK,Lakowski J,Wheway G
Sat Oct 01 00:00:00 EDT 2022
Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.
eLife
Pinskey JM,Hoard TM,Zhao XF,Franks NE,Frank ZC,McMellen AN,Giger RJ,Allen BL
Wed Sep 28 00:00:00 EDT 2022
Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia.
Bone research
Martin L,Kaci N,Benoist-Lasselin C,Mondoloni M,Decaudaveine S,Estibals V,Cornille M,Loisay L,Flipo J,Demuynck B,de la Luz Cádiz-Gurrea M,Barbault F,Fernández-Arroyo S,Schibler L,Segura-Carretero A,Dambroise E,Legeai-Mallet L
Tue Jan 25 00:00:00 EST 2022
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
Cell reports
Schembs L,Willems A,Hasenpusch-Theil K,Cooper JD,Whiting K,Burr K,Bøstrand SMK,Selvaraj BT,Chandran S,Theil T
Tue May 17 00:00:00 EDT 2022
Primary Cilia Restrain PI3K-AKT Signaling to Orchestrate Human Decidualization.
International journal of molecular sciences
Li B,Yan YP,Liang C,He YY,Wang Y,Li MY,Chen ST,Li Y,Liu AX,Yan GJ,Yang ZM
Thu Dec 08 00:00:00 EST 2022
Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis.
Cell stem cell
Ungricht R,Guibbal L,Lasbennes MC,Orsini V,Beibel M,Waldt A,Cuttat R,Carbone W,Basler A,Roma G,Nigsch F,Tchorz JS,Hoepfner D,Hoppe PS
Thu Jan 06 00:00:00 EST 2022
Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling.
JCI insight
Shi H,Wang H,Zhang C,Lu Y,Yao J,Chen Z,Xing G,Wei Q,Cao X
Tue Feb 22 00:00:00 EST 2022
Cytoskeletal Protein 4.1G Is Essential for the Primary Ciliogenesis and Osteoblast Differentiation in Bone Formation.
International journal of molecular sciences
Saito M,Hirano M,Izumi T,Mori Y,Ito K,Saitoh Y,Terada N,Sato T,Sukegawa J
Mon Feb 14 00:00:00 EST 2022
AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells.
International journal of molecular sciences
Revathidevi S,Hosomichi K,Natsume T,Nakaoka H,Fujito NT,Akatsuka H,Sato T,Munirajan AK,Inoue I
Thu Sep 22 00:00:00 EDT 2022
Chondrocyte-specific response to stiffness-mediated primary cilia formation and centriole positioning.
American journal of physiology. Cell physiology
Williantarra I,Leung S,Choi YS,Chhana A,McGlashan SR
Fri Jul 01 00:00:00 EDT 2022
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines.
Bio-protocol
Frikstad KM,Schink KO,Gilani S,Pedersen LB,Patzke S
Sun Mar 20 00:00:00 EDT 2022
Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial-Mesenchymal Transition in Culture.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ruiter FAA,Morgan FLC,Roumans N,Schumacher A,Slaats GG,Moroni L,LaPointe VLS,Baker MB
Fri Jul 01 00:00:00 EDT 2022
Characterization of TRPV4-mediated signaling pathways in an optimized human choroid plexus epithelial cell line.
American journal of physiology. Cell physiology
Hulme L,Hochstetler A,Schwerk C,Schroten H,Ishikawa H,Tung CY,Perrin B,Blazer-Yost B
Thu Dec 01 00:00:00 EST 2022
Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate.
Cell research
Hu A,Zhang JZ,Wang J,Li CC,Yuan M,Deng G,Lin ZC,Qiu ZP,Liu HY,Wang XW,Wei PC,He X,Zhao X,Qiu WW,Song BL
Tue Mar 01 00:00:00 EST 2022
Deletion of CEP164 in mouse photoreceptors post-ciliogenesis interrupts ciliary intraflagellar transport (IFT).
PLoS genetics
Reed M,Takemaru KI,Ying G,Frederick JM,Baehr W
Thu Sep 01 00:00:00 EDT 2022
Concurrent Germline and Somatic Mutations in FLCN and Preliminary Exploration of Its Function: A Case Report.
Frontiers in oncology
Wang T,Yang Y,Feng H,Cui B,Lv Z,Zhao W,Zhang X,Ma X
Sat Jul 16 00:00:00 EDT 2022
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis.
Cell discovery
Kuang W,Jin H,Yang F,Chen X,Liu J,Li T,Chang Y,Liu M,Xu Z,Huo C,Yan X,Yang Y,Liu W,Shu Q,Xie S,Zhou T
Fri Mar 11 00:00:00 EST 2022
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole.
The Journal of cell biology
Shen XL,Yuan JF,Qin XH,Song GP,Hu HB,Tu HQ,Song ZQ,Li PY,Xu YL,Li S,Jian XX,Li JN,He CY,Yu XP,Liang LY,Wu M,Han QY,Wang K,Li AL,Zhou T,Zhang YC,Wang N,Li HY
Mon Jan 03 00:00:00 EST 2022
Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses.
International journal of molecular sciences
Suiwal S,Dembla M,Schwarz K,Katiyar R,Jung M,Carius Y,Maxeiner S,Lauterbach MA,Lancaster CRD,Schmitz F
Mon Jun 27 00:00:00 EDT 2022
Hedgehog signaling is controlled by Rac1 activity.
Theranostics
Tang C,Wu X,Ren Q,Yao M,Xu S,Yan Z
Thu Apr 21 00:00:00 EDT 2022
ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal.
eLife
Jalalvand E,Alvelid J,Coceano G,Edwards S,Robertson B,Grillner S,Testa I
Tue Feb 01 00:00:00 EST 2022
CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
EMBO molecular medicine
He L,Arnold C,Thoma J,Rohde C,Kholmatov M,Garg S,Hsiao CC,Viol L,Zhang K,Sun R,Schmidt C,Janssen M,MacRae T,Huber K,Thiede C,Hébert J,Sauvageau G,Spratte J,Fluhr H,Aust G,Müller-Tidow C,Niehrs C,Pereira G,Hamann J,Tanaka M,Zaugg JB,Pabst C
Thu Apr 07 00:00:00 EDT 2022
The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization.
Biology open
Lara Ordóñez AJ,Fasiczka R,Fernández B,Naaldijk Y,Fdez E,Blanca Ramírez M,Phan S,Boassa D,Hilfiker S
Mon Aug 15 00:00:00 EDT 2022
TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling.
Cell reports
Sivakumar S,Qi S,Cheng N,Sathe AA,Kanchwala M,Kumar A,Evers BM,Xing C,Yu H
Tue Feb 15 00:00:00 EST 2022
C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane.
Cell reports
Hwang JY,Wang H,Lu Y,Ikawa M,Chung JJ
Tue Jan 18 00:00:00 EST 2022
LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport.
Journal of cell science
Hanafusa H,Kedashiro S,Gotoh M,Saitoh KH,Inaba H,Nishioka T,Kaibuchi K,Inagaki M,Hisamoto N,Matsumoto K
Tue Nov 01 00:00:00 EDT 2022
Mutations in SCNM1 cause orofaciodigital syndrome due to minor intron splicing defects affecting primary cilia.
American journal of human genetics
Iturrate A,Rivera-Barahona A,Flores CL,Otaify GA,Elhossini R,Perez-Sanz ML,Nevado J,Tenorio-Castano J,Triviño JC,Garcia-Gonzalo FR,Piceci-Sparascio F,De Luca A,Martínez L,Kalaycı T,Lapunzina P,Altunoglu U,Aglan M,Abdalla E,Ruiz-Perez VL
Thu Oct 06 00:00:00 EDT 2022
Primary Cilium by Polyinosinic:Polycytidylic Acid Regulates the Regenerative Migration of Beas-2B Bronchial Epithelial Cells.
Biomolecules & therapeutics
Gweon B,Jang TK,Thuy PX,Moon EY
Tue Mar 01 00:00:00 EST 2022
Modulation of Primary Cilia by Alvocidib Inhibition of CILK1.
International journal of molecular sciences
Wang EX,Turner JS,Brautigan DL,Fu Z
Sat Jul 23 00:00:00 EDT 2022
Primary cilia suppress Ripk3-mediated necroptosis.
Cell death discovery
Kieckhöfer E,Slaats GG,Ebert LK,Albert MC,Dafinger C,Kashkar H,Benzing T,Schermer B
Fri Dec 02 00:00:00 EST 2022
Subtype-Selective Positive Modulation of KCa2.3 Channels Increases Cilia Length.
ACS chemical biology
Nam YW,Pala R,El-Sayed NS,Larin-Henriquez D,Amirrad F,Yang G,Rahman MA,Orfali R,Downey M,Parang K,Nauli SM,Zhang M
Fri Aug 19 00:00:00 EDT 2022
Metabolomic fingerprinting of renal disease progression in Bardet-Biedl syndrome reveals mitochondrial dysfunction in kidney tubular cells.
iScience
Marchese E,Caterino M,Viggiano D,Cevenini A,Tolone S,Docimo L,Di Iorio V,Del Vecchio Blanco F,Fedele R,Simonelli F,Perna A,Nigro V,Capasso G,Ruoppolo M,Zacchia M
Fri Nov 18 00:00:00 EST 2022
Midbody plays an active role in fibroblast-myofibroblast transition by mediating TGF-β signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jung SW,Kim SM,Kim A,Park SH,Moon JY,Lee SH
Sun May 01 00:00:00 EDT 2022
Midbody plays an active role in fibroblast-myofibroblast transition by mediating TGF-β signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jung SW,Kim SM,Kim A,Park SH,Moon JY,Lee SH
Sun May 01 00:00:00 EDT 2022
Midbody plays an active role in fibroblast-myofibroblast transition by mediating TGF-β signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jung SW,Kim SM,Kim A,Park SH,Moon JY,Lee SH
Sun May 01 00:00:00 EDT 2022
Midbody plays an active role in fibroblast-myofibroblast transition by mediating TGF-β signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jung SW,Kim SM,Kim A,Park SH,Moon JY,Lee SH
Sun May 01 00:00:00 EDT 2022
Endothelial β-arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia.
Pulmonary circulation
Park S,Ma Z,Zarkada G,Papangeli I,Paluri S,Nazo N,Rivera-Molina F,Toomre D,Rajagopal S,Chun HJ
Sat Oct 01 00:00:00 EDT 2022
Carnitine Protects against MPP+-Induced Neurotoxicity and Inflammation by Promoting Primary Ciliogenesis in SH-SY5Y Cells.
Cells
Bae JE,Kim JB,Jo DS,Park NY,Kim YH,Lee HJ,Kim SH,Kim SH,Son M,Kim P,Ryu HY,Lee WH,Ryoo ZY,Lee HS,Jung YK,Cho DH
Thu Sep 01 00:00:00 EDT 2022
KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells.
Life science alliance
Mashima Y,Nohira H,Sugihara H,Dynlacht BD,Kobayashi T,Itoh H
Tue Nov 01 00:00:00 EDT 2022
Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.
Cell and tissue research
Sheng X,Gao S,Sheng Y,Xie X,Wang J,He Y
Sat Jan 01 00:00:00 EST 2022
Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.
Cell and tissue research
Sheng X,Gao S,Sheng Y,Xie X,Wang J,He Y
Sat Jan 01 00:00:00 EST 2022
The N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells.
Small GTPases
Oguchi ME,Homma Y,Fukuda M
Sat Jan 01 00:00:00 EST 2022
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic.
Molecular biology of the cell
Turn RE,Hu Y,Dewees SI,Devi N,East MP,Hardin KR,Khatib T,Linnert J,Wolfrum U,Lim MJ,Casanova JE,Caspary T,Kahn RA
Tue Feb 01 00:00:00 EST 2022
The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients.
Cells
Saber Cherif L,Diabasana Z,Perotin JM,Ancel J,Petit LMG,Devilliers MA,Bonnomet A,Lalun N,Delepine G,Maskos U,Gosset P,Polette M,Muggeo A,Guillard T,Deslée G,Dormoy V
Tue Sep 20 00:00:00 EDT 2022
Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement.
iScience
Fdez E,Madero-Pérez J,Lara Ordóñez AJ,Naaldijk Y,Fasiczka R,Aiastui A,Ruiz-Martínez J,López de Munain A,Cowley SA,Wade-Martins R,Hilfiker S
Fri Jun 17 00:00:00 EDT 2022
Biallelic loss-of-function variants in EXOC6B are associated with impaired primary ciliogenesis and cause spondylo-epi-metaphyseal dysplasia with joint laxity type 3.
Human mutation
Simsek-Kiper PO,Jacob P,Upadhyai P,Taşkıran ZE,Guleria VS,Karaosmanoglu B,Imren G,Gocmen R,Bhavani GS,Kausthubham N,Shah H,Utine GE,Boduroglu K,Girisha KM
Thu Dec 01 00:00:00 EST 2022
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation.
EMBO reports
Hansen JN,Kaiser F,Leyendecker P,Stüven B,Krause JH,Derakhshandeh F,Irfan J,Sroka TJ,Preval KM,Desai PB,Kraut M,Theis H,Drews AD,De-Domenico E,Händler K,Pazour GJ,Henderson DJP,Mick DU,Wachten D
Wed Aug 03 00:00:00 EDT 2022
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling.
Journal of cell science
Morthorst SK,Nielsen C,Farinelli P,Anvarian Z,Rasmussen CBR,Serra-Marques A,Grigoriev I,Altelaar M,Fürstenberg N,Ludwig A,Akhmanova A,Christensen ST,Pedersen LB
Wed Jun 15 00:00:00 EDT 2022
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development.
Cell death and differentiation
Li Q,Han Z,Singh N,Terré B,Fame RM,Arif U,Page TD,Zahran T,Abdeltawab A,Huang Y,Cao P,Wang J,Lu H,Lidov HGW,Surendran K,Wu L,Virga JQ,Zhao YT,Schüller U,Wechsler-Reya RJ,Lehtinen MK,Roy S,Liu Z,Stracker TH,Zhao H
Mon Aug 01 00:00:00 EDT 2022
Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
Biochemical pharmacology
Thirugnanam K,Prabhudesai S,Van Why E,Pan A,Gupta A,Foreman K,Zennadi R,Rarick KR,Nauli SM,Palecek SP,Ramchandran R
Mon Aug 01 00:00:00 EDT 2022
Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
Biochemical pharmacology
Thirugnanam K,Prabhudesai S,Van Why E,Pan A,Gupta A,Foreman K,Zennadi R,Rarick KR,Nauli SM,Palecek SP,Ramchandran R
Mon Aug 01 00:00:00 EDT 2022
Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
Biochemical pharmacology
Thirugnanam K,Prabhudesai S,Van Why E,Pan A,Gupta A,Foreman K,Zennadi R,Rarick KR,Nauli SM,Palecek SP,Ramchandran R
Mon Aug 01 00:00:00 EDT 2022
Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
Biochemical pharmacology
Thirugnanam K,Prabhudesai S,Van Why E,Pan A,Gupta A,Foreman K,Zennadi R,Rarick KR,Nauli SM,Palecek SP,Ramchandran R
Mon Aug 01 00:00:00 EDT 2022
Fluorescence imaging of beta cell primary cilia.
Frontiers in endocrinology
Li ZA,Cho JH,Woodhams LG,Hughes JW
Tue Oct 11 00:00:00 EDT 2022
A Potent Antagonist of Smoothened in Hedgehog Signaling for Epilepsy.
International journal of molecular sciences
Fan J,Zhao Z,Liu R,Li H,He W,Wu J,Wang Y,Chen W
Tue Nov 22 00:00:00 EST 2022
Cilia-Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yamakawa D,Tsuboi J,Kasahara K,Matsuda C,Nishimura Y,Kodama T,Katayama N,Watanabe M,Inagaki M
Mon Nov 14 00:00:00 EST 2022
Heterozygous variants in MYH10 associated with neurodevelopmental disorders and congenital anomalies with evidence for primary cilia-dependent defects in Hedgehog signaling.
Genetics in medicine : official journal of the American College of Medical Genetics
Holtz AM,VanCoillie R,Vansickle EA,Carere DA,Withrow K,Torti E,Juusola J,Millan F,Person R,Guillen Sacoto MJ,Si Y,Wentzensen IM,Pugh J,Vasileiou G,Rieger M,Reis A,Argilli E,Sherr EH,Aldinger KA,Dobyns WB,Brunet T,Hoefele J,Wagner M,Haber B,Kotzaeridou U,Keren B,Heron D,Mignot C,Heide S,Courtin T,Buratti J,Murugasen S,Donald KA,O'Heir E,Moody S,Kim KH,Burton BK,Yoon G,Campo MD,Masser-Frye D,Kozenko M,Parkinson C,Sell SL,Gordon PL,Prokop JW,Karaa A,Bupp C,Raby BA
Sat Oct 01 00:00:00 EDT 2022
Control of meiotic chromosomal bouquet and germ cell morphogenesis by the zygotene cilium.
Science (New York, N.Y.)
Mytlis A,Kumar V,Qiu T,Deis R,Hart N,Levy K,Masek M,Shawahny A,Ahmad A,Eitan H,Nather F,Adar-Levor S,Birnbaum RY,Elia N,Bachmann-Gagescu R,Roy S,Elkouby YM
Fri Jun 17 00:00:00 EDT 2022
Distribution of prototypical primary cilia markers in subtypes of retinal ganglion cells.
The Journal of comparative neurology
Kowal TJ,Dhande OS,Wang B,Wang Q,Ning K,Liu W,Berbari NF,Hu Y,Sun Y
Mon Aug 01 00:00:00 EDT 2022
The Primary Ciliary Deficits in Cerebellar Bergmann Glia of the Mouse Model of Fragile X Syndrome.
Cerebellum (London, England)
Lee B,Beuhler L,Lee HY
Sat Oct 01 00:00:00 EDT 2022
TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human.
Frontiers in molecular neuroscience
Delalande JM,Nagy N,McCann CJ,Natarajan D,Cooper JE,Carreno G,Dora D,Campbell A,Laurent N,Kemos P,Thomas S,Alby C,Attié-Bitach T,Lyonnet S,Logan MP,Goldstein AM,Davey MG,Hofstra RMW,Thapar N,Burns AJ
Sat Jul 16 00:00:00 EDT 2022
Loss of Ciliary Gene Bbs8 Results in Physiological Defects in the Retinal Pigment Epithelium.
Frontiers in cell and developmental biology
Schneider S,De Cegli R,Nagarajan J,Kretschmer V,Matthiessen PA,Intartaglia D,Hotaling N,Ueffing M,Boldt K,Conte I,May-Simera HL
Wed Mar 10 00:00:00 EST 2021
A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities.
Human molecular genetics
Bentley-Ford MR,Engle SE,Clearman KR,Haycraft CJ,Andersen RS,Croyle MJ,Rains AB,Berbari NF,Yoder BK
Mon Apr 26 00:00:00 EDT 2021
Roles for ELMOD2 and Rootletin in ciliogenesis.
Molecular biology of the cell
Turn RE,Linnert J,Gigante ED,Wolfrum U,Caspary T,Kahn RA
Thu Apr 15 00:00:00 EDT 2021
Cilium induction triggers differentiation of glioma stem cells.
Cell reports
Goranci-Buzhala G,Mariappan A,Ricci-Vitiani L,Josipovic N,Pacioni S,Gottardo M,Ptok J,Schaal H,Callaini G,Rajalingam K,Dynlacht B,Hadian K,Papantonis A,Pallini R,Gopalakrishnan J
Tue Sep 07 00:00:00 EDT 2021
Cilium induction triggers differentiation of glioma stem cells.
Cell reports
Goranci-Buzhala G,Mariappan A,Ricci-Vitiani L,Josipovic N,Pacioni S,Gottardo M,Ptok J,Schaal H,Callaini G,Rajalingam K,Dynlacht B,Hadian K,Papantonis A,Pallini R,Gopalakrishnan J
Tue Sep 07 00:00:00 EDT 2021
Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.
Developmental dynamics : an official publication of the American Association of Anatomists
Gailey CD,Wang EJ,Jin L,Ahmadi S,Brautigan DL,Li X,Xu W,Scott MM,Fu Z
Mon Feb 01 00:00:00 EST 2021
Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.
Molecular cell
Piette BL,Alerasool N,Lin ZY,Lacoste J,Lam MHY,Qian WW,Tran S,Larsen B,Campos E,Peng J,Gingras AC,Taipale M
Thu Jun 17 00:00:00 EDT 2021
CiliaQ: a simple, open-source software for automated quantification of ciliary morphology and fluorescence in 2D, 3D, and 4D images.
The European physical journal. E, Soft matter
Hansen JN,Rassmann S,Stüven B,Jurisch-Yaksi N,Wachten D
Mon Mar 08 00:00:00 EST 2021
Time-resolved proteomics profiling of the ciliary Hedgehog response.
The Journal of cell biology
May EA,Kalocsay M,D'Auriac IG,Schuster PS,Gygi SP,Nachury MV,Mick DU
Mon May 03 00:00:00 EDT 2021
Time-resolved proteomics profiling of the ciliary Hedgehog response.
The Journal of cell biology
May EA,Kalocsay M,D'Auriac IG,Schuster PS,Gygi SP,Nachury MV,Mick DU
Mon May 03 00:00:00 EDT 2021
Modeling retinitis pigmentosa through patient-derived retinal organoids.
STAR protocols
Li YP,Deng WL,Jin ZB
Fri Jun 18 00:00:00 EDT 2021
Differential Roles of Tubby Family Proteins in Ciliary Formation and Trafficking.
Molecules and cells
Hong JJ,Kim KE,Park SY,Bok J,Seo JT,Moon SJ
Tue Aug 31 00:00:00 EDT 2021
Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles.
Nature communications
Volz AK,Frei A,Kretschmer V,de Jesus Domingues AM,Ketting RF,Ueffing M,Boldt K,Krämer-Albers EM,May-Simera HL
Mon Sep 27 00:00:00 EDT 2021
Primary Cilia Mediate TSH-Regulated Thyroglobulin Endocytic Pathways.
Frontiers in endocrinology
Lee J,Sul HJ,Kim KH,Chang JY,Shong M
Fri Feb 11 00:00:00 EST 2022
Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis.
Cell reports
Yamakawa D,Katoh D,Kasahara K,Shiromizu T,Matsuyama M,Matsuda C,Maeno Y,Watanabe M,Nishimura Y,Inagaki M
Tue Mar 09 00:00:00 EST 2021
Gene replacement therapy restores RCBTB1 expression and cilium length in patient-derived retinal pigment epithelium.
Journal of cellular and molecular medicine
Huang Z,Zhang D,Chen SC,Jennings L,Carvalho LS,Fletcher S,Chen FK,McLenachan S
Mon Nov 01 00:00:00 EDT 2021
TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity.
The Journal of cell biology
Meitinger F,Kong D,Ohta M,Desai A,Oegema K,Loncarek J
Mon Jul 05 00:00:00 EDT 2021
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
PloS one
Datta P,Cribbs JT,Seo S
Wed Oct 06 00:00:00 EDT 2021
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
PloS one
Datta P,Cribbs JT,Seo S
Wed Oct 06 00:00:00 EDT 2021
The type 3 adenylyl cyclase is crucial for intestinal mucosal neural network in the gut lamina propria.
Neurogastroenterology and motility
Zhou K,Zhou Y,Yang D,Chen T,Liu X,Li S,Wang Z
Wed Sep 01 00:00:00 EDT 2021
Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway.
Current biology : CB
Ganga AK,Kennedy MC,Oguchi ME,Gray S,Oliver KE,Knight TA,De La Cruz EM,Homma Y,Fukuda M,Breslow DK
Mon Jul 12 00:00:00 EDT 2021
The 3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase EBP inhibits cholesterylation of Smoothened.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Qiu ZP,Hu A,Song BL
Wed Dec 01 00:00:00 EST 2021
Nonredundant roles of DIAPHs in primary ciliogenesis.
The Journal of biological chemistry
Palander O,Lam A,Collins RF,Moraes TJ,Trimble WS
Fri Aug 20 00:00:00 EDT 2021
Human cells lacking CDC14A and CDC14B show differences in ciliogenesis but not in mitotic progression.
Journal of cell science
Partscht P,Uddin B,Schiebel E
Wed Jan 27 00:00:00 EST 2021
2-IPMA Ameliorates PM2.5-Induced Inflammation by Promoting Primary Ciliogenesis in RPE Cells.
Molecules (Basel, Switzerland)
Choi JY,Bae JE,Kim JB,Jo DS,Park NY,Kim YH,Lee HJ,Kim SH,Kim SH,Jeon HB,Na HW,Choi H,Ryu HY,Ryoo ZY,Lee HS,Cho DH
Mon Sep 06 00:00:00 EDT 2021
Biallelic deep intronic variant c.5457+81T>A in TRIP11 causes loss of function and results in achondrogenesis 1A.
Human mutation
Upadhyai P,Radhakrishnan P,Guleria VS,Kausthubham N,Nayak SS,Superti-Furga A,Girisha KM
Sun Aug 01 00:00:00 EDT 2021
Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle.
Scientific reports
Waisman A,Norris AM,Elías Costa M,Kopinke D
Thu Jun 03 00:00:00 EDT 2021
Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hor CHH,Lo JCW,Cham ALS,Leong WY,Goh ELK
Wed Aug 11 00:00:00 EDT 2021
Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hor CHH,Lo JCW,Cham ALS,Leong WY,Goh ELK
Wed Aug 11 00:00:00 EDT 2021
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity.
Developmental cell
Xie C,Abrams SR,Herranz-Pérez V,García-Verdugo JM,Reiter JF
Mon Dec 20 00:00:00 EST 2021
Expression of α-Tubulin Acetyltransferase 1 and Tubulin Acetylation as Selective Forces in Cell Competition.
Cells
Rahimi AM,Cai M,Kılı¿ I,Kazerouni ZB,Tapia Contreras C,Hoyer-Fender S
Sun Feb 14 00:00:00 EST 2021
Quantitative Determination of Primary Cilia Protein Distribution Using Immunofluorescence Staining and MATLAB Analysis.
Bio-protocol
Jenks AD,Fivaz M,Tanos BE
Sun Dec 05 00:00:00 EST 2021
LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade.
Life science alliance
Dhekne HS,Yanatori I,Vides EG,Sobu Y,Diez F,Tonelli F,Pfeffer SR
Sat May 01 00:00:00 EDT 2021
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels.
eLife
Gonçalves AB,Hasselbalch SK,Joensen BB,Patzke S,Martens P,Ohlsen SK,Quinodoz M,Nikopoulos K,Suleiman R,Damsø Jeppesen MP,Weiss C,Christensen ST,Rivolta C,Andersen JS,Farinelli P,Pedersen LB
Wed Jul 14 00:00:00 EDT 2021
Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement.
Journal of medicinal chemistry
Zhao F,Wu Y,Zhou F,Xue D,Zhao S,Lu W,Liu X,Hu T,Qiu Y,Li R,Gu T,Xu Y,Xu F,Zhong G,Jiang Z,Zhao S,Tao H
Thu Sep 23 00:00:00 EDT 2021
A ZFYVE19 gene mutation associated with neonatal cholestasis and cilia dysfunction: case report with a novel pathogenic variant.
Orphanet journal of rare diseases
Mandato C,Siano MA,Nazzaro L,Gelzo M,Francalanci P,Rizzo F,D'Agostino Y,Morleo M,Brillante S,Weisz A,Franco B,Vajro P
Wed Apr 14 00:00:00 EDT 2021
Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms.
iScience
Speight P,Rozycki M,Venugopal S,Szászi K,Kofler M,Kapus A
Fri Jul 23 00:00:00 EDT 2021
Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms.
iScience
Speight P,Rozycki M,Venugopal S,Szászi K,Kofler M,Kapus A
Fri Jul 23 00:00:00 EDT 2021
Human brain organoids assemble functionally integrated bilateral optic vesicles.
Cell stem cell
Gabriel E,Albanna W,Pasquini G,Ramani A,Josipovic N,Mariappan A,Schinzel F,Karch CM,Bao G,Gottardo M,Suren AA,Hescheler J,Nagel-Wolfrum K,Persico V,Rizzoli SO,Altmüller J,Riparbelli MG,Callaini G,Goureau O,Papantonis A,Busskamp V,Schneider T,Gopalakrishnan J
Thu Oct 07 00:00:00 EDT 2021
Identification of Cilia in Different Mouse Tissues.
Cells
Li X,Yang S,Deepak V,Chinipardaz Z,Yang S
Tue Jun 29 00:00:00 EDT 2021
Investigating Primary Cilia during Peripheral Nervous System Formation.
International journal of molecular sciences
Yusifov E,Dumoulin A,Stoeckli ET
Sat Mar 20 00:00:00 EDT 2021
Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Nature
Willnow D,Benary U,Margineanu A,Vignola ML,Konrath F,Pongrac IM,Karimaddini Z,Vigilante A,Wolf J,Spagnoli FM
Wed Sep 01 00:00:00 EDT 2021
Exocyst complex mediates recycling of internal cilia.
Current biology : CB
Rivera-Molina FE,Xi Z,Reales E,Wang B,Toomre D
Mon Dec 20 00:00:00 EST 2021
Increase in primary cilia in the epidermis of patients with atopic dermatitis and psoriasis.
Experimental dermatology
Rizaldy D,Toriyama M,Kato H,Fukui R,Fujita F,Nakamura M,Okada F,Morita A,Ishii KJ
Tue Jun 01 00:00:00 EDT 2021
Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome.
Genetics in medicine : official journal of the American College of Medical Genetics
Luo M,Lin Z,Zhu T,Jin M,Meng D,He R,Cao Z,Shen Y,Lu C,Cai R,Zhao Y,Wang X,Li H,Wu S,Zou X,Luo G,Cao L,Huang M,Jiao H,Gao H,Sui R,Zhao C,Ma X,Cao M
Tue Jun 01 00:00:00 EDT 2021
Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling.
Frontiers in cell and developmental biology
Bernatik O,Paclikova P,Kotrbova A,Bryja V,Cajanek L
Tue Mar 16 00:00:00 EDT 2021
MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis.
Cancers
Pietrobono S,Franci L,Imperatore F,Zanini C,Stecca B,Chiariello M
Wed Sep 29 00:00:00 EDT 2021
Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import.
Molecular biology of the cell
Kobayashi T,Ishida Y,Hirano T,Katoh Y,Nakayama K
Fri Jan 01 00:00:00 EST 2021
Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response.
Cell death and differentiation
Chen TY,Huang BM,Tang TK,Chao YY,Xiao XY,Lee PR,Yang LY,Wang CY
Tue Jun 01 00:00:00 EDT 2021
Sequences in the stalk domain regulate auto-inhibition and ciliary tip localization of the immotile kinesin-4 KIF7.
Journal of cell science
Blasius TL,Yue Y,Prasad R,Liu X,Gennerich A,Verhey KJ
Thu Jul 01 00:00:00 EDT 2021
Ciliary Hedgehog signaling regulates cell survival to build the facial midline.
eLife
Abrams SR,Reiter JF
Thu Oct 21 00:00:00 EDT 2021
DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.
Developmental dynamics : an official publication of the American Association of Anatomists
Guo L,Beck T,Fulmer D,Ramos-Ortiz S,Glover J,Wang C,Moore K,Gensemer C,Morningstar J,Moore R,Schott JJ,Le Tourneau T,Koren N,Norris RA
Fri Oct 01 00:00:00 EDT 2021
Primary Ciliogenesis by 2-Isopropylmalic Acid Prevents PM2.5-Induced Inflammatory Response and MMP-1 Activation in Human Dermal Fibroblasts and a 3-D-Skin Model.
International journal of molecular sciences
Bae JE,Min D,Choi JY,Choi H,Kim JB,Park NY,Jo DS,Kim YH,Na HW,Kim YJ,Kim ES,Kim HJ,Cho DH
Sun Oct 10 00:00:00 EDT 2021
A CRISPR and high-content imaging assay compliant with ACMG/AMP guidelines for clinical variant interpretation in ciliopathies.
Human genetics
Nazlamova L,Thomas NS,Cheung MK,Legebeke J,Lord J,Pengelly RJ,Tapper WJ,Wheway G
Thu Apr 01 00:00:00 EDT 2021
Impaired Ciliary Beat Frequency and Ciliogenesis Alteration during Airway Epithelial Cell Differentiation in COPD.
Diagnostics (Basel, Switzerland)
Ancel J,Belgacemi R,Diabasana Z,Perotin JM,Bonnomet A,Dewolf M,Launois C,Mulette P,Deslée G,Polette M,Dormoy V
Tue Aug 31 00:00:00 EDT 2021
A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia.
eLife
Quidwai T,Wang J,Hall EA,Petriman NA,Leng W,Kiesel P,Wells JN,Murphy LC,Keighren MA,Marsh JA,Lorentzen E,Pigino G,Mill P
Thu Nov 04 00:00:00 EDT 2021
Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis.
eLife
Gopalan J,Omar MH,Roy A,Cruz NM,Falcone J,Jones KN,Forbush KA,Himmelfarb J,Freedman BS,Scott JD
Mon Jul 12 00:00:00 EDT 2021
Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis.
Journal of the American Heart Association
Morningstar JE,Gensemer C,Moore R,Fulmer D,Beck TC,Wang C,Moore K,Guo L,Sieg F,Nagata Y,Bertrand P,Spampinato RA,Glover J,Poelzing S,Gourdie RG,Watts K,Richardson WJ,Levine RA,Borger MA,Norris RA
Tue Dec 21 00:00:00 EST 2021
Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis.
Journal of the American Heart Association
Morningstar JE,Gensemer C,Moore R,Fulmer D,Beck TC,Wang C,Moore K,Guo L,Sieg F,Nagata Y,Bertrand P,Spampinato RA,Glover J,Poelzing S,Gourdie RG,Watts K,Richardson WJ,Levine RA,Borger MA,Norris RA
Tue Dec 21 00:00:00 EST 2021
Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis.
Journal of the American Heart Association
Morningstar JE,Gensemer C,Moore R,Fulmer D,Beck TC,Wang C,Moore K,Guo L,Sieg F,Nagata Y,Bertrand P,Spampinato RA,Glover J,Poelzing S,Gourdie RG,Watts K,Richardson WJ,Levine RA,Borger MA,Norris RA
Tue Dec 21 00:00:00 EST 2021
Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis.
Journal of the American Heart Association
Morningstar JE,Gensemer C,Moore R,Fulmer D,Beck TC,Wang C,Moore K,Guo L,Sieg F,Nagata Y,Bertrand P,Spampinato RA,Glover J,Poelzing S,Gourdie RG,Watts K,Richardson WJ,Levine RA,Borger MA,Norris RA
Tue Dec 21 00:00:00 EST 2021
Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis.
Scientific reports
Cyge B,Voronina V,Hoque M,Kim EN,Hall J,Bailey-Lundberg JM,Pazour GJ,Crawford HC,Moon RT,Li FQ,Takemaru KI
Thu Aug 26 00:00:00 EDT 2021
ATXN10 Is Required for Embryonic Heart Development and Maintenance of Epithelial Cell Phenotypes in the Adult Kidney and Pancreas.
Frontiers in cell and developmental biology
Bentley-Ford MR,Andersen RS,Croyle MJ,Haycraft CJ,Clearman KR,Foote JB,Reiter JF,Yoder BK
Sat May 20 00:00:00 EDT 2023
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
The Journal of cell biology
Kumar D,Rains A,Herranz-Pérez V,Lu Q,Shi X,Swaney DL,Stevenson E,Krogan NJ,Huang B,Westlake C,Garcia-Verdugo JM,Yoder BK,Reiter JF
Mon Sep 06 00:00:00 EDT 2021
Functional inhibition of fatty acid binding protein 4 ameliorates impaired ciliogenesis in GCs.
Biochemical and biophysical research communications
Jung Y,Cho SM,Kim S,Cheong JH,Kwon HJ
Fri Feb 05 00:00:00 EST 2021
Sub-toxic levels of cobalt ions impair chondrocyte mechanostranduction via HDAC6-dependent primary cilia shortening.
Biochemical and biophysical research communications
Wu H,Wang Z,Liu S,Meng H,Liu S,Fu S
Fri Mar 12 00:00:00 EST 2021
WDR35 is involved in subcellular localization of acetylated tubulin in 293T cells.
Biochemical and biophysical research communications
Sekiguchi T,Ishii T,Kobayashi H,Furuno N
Fri Apr 02 00:00:00 EDT 2021
YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development.
Developmental biology
Lavado A,Gangwar R,Paré J,Wan S,Fan Y,Cao X
Wed Dec 01 00:00:00 EST 2021
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.
Science advances
Chen C,Xu Q,Zhang Y,Davies BA,Huang Y,Katzmann DJ,Harris PC,Hu J,Ling K
Tue Jun 01 00:00:00 EDT 2021
Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons.
Experimental neurobiology
Kim H,Sim H,Lee JE,Seo MK,Lim J,Bang Y,Nam D,Lee SY,Chung SK,Choi HJ,Park SW,Son I,Kim J,Seol W
Wed Jun 30 00:00:00 EDT 2021
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Antioxidants (Basel, Switzerland)
Mustafa R,Rawas C,Mannal N,Kreiner G,Spittau B,Kamińska K,Yilmaz R,Pötschke C,Kirsch J,Liss B,Tucker KL,Parlato R
Fri Aug 13 00:00:00 EDT 2021
LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis.
Nature communications
Hu HB,Song ZQ,Song GP,Li S,Tu HQ,Wu M,Zhang YC,Yuan JF,Li TT,Li PY,Xu YL,Shen XL,Han QY,Li AL,Zhou T,Chun J,Zhang XM,Li HY
Thu Jan 28 00:00:00 EST 2021
Recombinant Antithrombin Attenuates Acute Respiratory Distress Syndrome in Experimental Endotoxemia.
The American journal of pathology
Okamoto H,Muraki I,Okada H,Tomita H,Suzuki K,Takada C,Wakayama Y,Kuroda A,Fukuda H,Kawasaki Y,Nishio A,Matsuo M,Tamaoki Y,Inagawa R,Takashima S,Taniguchi T,Suzuki A,Suzuki K,Miyazaki N,Kakino Y,Yasuda R,Fukuta T,Kitagawa Y,Miyake T,Doi T,Yoshida T,Yoshida S,Ogura S
Wed Sep 01 00:00:00 EDT 2021
BBS Proteins Affect Ciliogenesis and Are Essential for Hedgehog Signaling, but Not for Formation of iPSC-Derived RPE-65 Expressing RPE-Like Cells.
International journal of molecular sciences
Hey CAB,Larsen LJ,Tümer Z,Brøndum-Nielsen K,Grønskov K,Hjortshøj TD,Møller LB
Fri Jan 29 00:00:00 EST 2021
Centriolar Protein C2cd3 Is Required for Craniofacial Development.
Frontiers in cell and developmental biology
Chang CF,Brown KM,Yang Y,Brugmann SA
Sat Jul 16 00:00:00 EDT 2022
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Brain : a journal of neurology
Shireman JM,Atashi F,Lee G,Ali ES,Saathoff MR,Park CH,Savchuk S,Baisiwala S,Miska J,Lesniak MS,James CD,Stupp R,Kumthekar P,Horbinski CM,Ben-Sahra I,Ahmed AU
Fri May 07 00:00:00 EDT 2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Brain : a journal of neurology
Shireman JM,Atashi F,Lee G,Ali ES,Saathoff MR,Park CH,Savchuk S,Baisiwala S,Miska J,Lesniak MS,James CD,Stupp R,Kumthekar P,Horbinski CM,Ben-Sahra I,Ahmed AU
Fri May 07 00:00:00 EDT 2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Brain : a journal of neurology
Shireman JM,Atashi F,Lee G,Ali ES,Saathoff MR,Park CH,Savchuk S,Baisiwala S,Miska J,Lesniak MS,James CD,Stupp R,Kumthekar P,Horbinski CM,Ben-Sahra I,Ahmed AU
Fri May 07 00:00:00 EDT 2021
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Journal of cell science
Grosch M,Brunner K,Ilyaskin AV,Schober M,Staudner T,Schmied D,Stumpp T,Schmidt KN,Madej MG,Pessoa TD,Othmen H,Kubitza M,Osten L,de Vries U,Mair MM,Somlo S,Moser M,Kunzelmann K,Ziegler C,Haerteis S,Korbmacher C,Witzgall R
Sun Aug 15 00:00:00 EDT 2021
Identification and characterization of primary cilia-positive salivary gland tumours exhibiting basaloid/myoepithelial differentiation.
The Journal of pathology
Shinmura K,Kusafuka K,Kawasaki H,Kato H,Hariyama T,Tsuchiya K,Kawanishi Y,Funai K,Misawa K,Mineta H,Sugimura H
Sun Aug 01 00:00:00 EDT 2021
Exovesicular-Shh confers Imatinib resistance by upregulating Bcl2 expression in chronic myeloid leukemia with variant chromosomes.
Cell death & disease
Dalal H,Subramanian S,V P S,Gowda DA,H K,Damodar S,Vyas N
Thu Mar 11 00:00:00 EST 2021
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
The EMBO journal
Duan S,Li H,Zhang Y,Yang S,Chen Y,Qiu B,Huang C,Wang J,Li J,Zhu X,Yan X
Fri Jan 15 00:00:00 EST 2021
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
The EMBO journal
Duan S,Li H,Zhang Y,Yang S,Chen Y,Qiu B,Huang C,Wang J,Li J,Zhu X,Yan X
Fri Jan 15 00:00:00 EST 2021
Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis.
Nature communications
Kwon OS,Mishra R,Safieddine A,Coleno E,Alasseur Q,Faucourt M,Barbosa I,Bertrand E,Spassky N,Le Hir H
Mon Mar 01 00:00:00 EST 2021
Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis.
Journal of lipid research
Tripathi P,Zhu Z,Qin H,Elsherbini A,Crivelli SM,Roush E,Wang G,Spassieva SD,Bieberich E
Thu Mar 10 00:00:00 EST 2022
Application of green tea catechins, polysaccharides, and flavonol prevent fine dust induced bronchial damage by modulating inflammation and airway cilia.
Scientific reports
Kim J,Choi H,Choi DH,Park K,Kim HJ,Park M
Tue Jan 26 00:00:00 EST 2021
Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry.
Biology open
Qiu H,Fujisawa S,Nozaki S,Katoh Y,Nakayama K
Mon Jan 25 00:00:00 EST 2021
Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells.
Cells
Qatato M,Venugopalan V,Al-Hashimi A,Rehders M,Valentine AD,Hein Z,Dallto U,Springer S,Brix K
Wed Jun 16 00:00:00 EDT 2021
TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection.
Thorax
Pearson H,Todd EJAA,Ahrends M,Hover SE,Whitehouse A,Stacey M,Lippiat JD,Wilkens L,Fieguth HG,Danov O,Hesse C,Barr JN,Mankouri J
Fri Jan 01 00:00:00 EST 2021
Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis.
PLoS genetics
Rashidieh B,Shohayeb B,Bain AL,Fortuna PRJ,Sinha D,Burgess A,Mills R,Adams RC,Lopez JA,Blumbergs P,Finnie J,Kalimutho M,Piper M,Hudson JE,Ng DCH,Khanna KK
Fri Oct 01 00:00:00 EDT 2021
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity.
Nature communications
Kyrousi C,O'Neill AC,Brazovskaja A,He Z,Kielkowski P,Coquand L,Di Giaimo R,D' Andrea P,Belka A,Forero Echeverry A,Mei D,Lenge M,Cruceanu C,Buchsbaum IY,Khattak S,Fabien G,Binder E,Elmslie F,Guerrini R,Baffet AD,Sieber SA,Treutlein B,Robertson SP,Cappello S
Tue Nov 02 00:00:00 EDT 2021
Induction of inverted morphology in brain organoids by vertical-mixing bioreactors.
Communications biology
Suong DNA,Imamura K,Inoue I,Kabai R,Sakamoto S,Okumura T,Kato Y,Kondo T,Yada Y,Klein WL,Watanabe A,Inoue H
Fri Oct 22 00:00:00 EDT 2021
Rab34 is necessary for early stages of intracellular ciliogenesis.
Current biology : CB
Stuck MW,Chong WM,Liao JC,Pazour GJ
Mon Jul 12 00:00:00 EDT 2021
DAB2IP modulates primary cilia formation associated with renal tumorigenesis.
Neoplasia (New York, N.Y.)
Lin CJ,Dang A,Hernandez E,Hsieh JT
Fri Jan 01 00:00:00 EST 2021
Deletion of Sox9 in the liver leads to hepatic cystogenesis in mice by transcriptionally downregulating Sec63.
The Journal of pathology
Xu WP,Cui YL,Chen LL,Ding K,Ding CH,Chen F,Zhang X,Xie WF
Sat May 01 00:00:00 EDT 2021
Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Development (Cambridge, England)
Mecklenburg N,Kowalczyk I,Witte F,Görne J,Laier A,Mamo TM,Gonschior H,Lehmann M,Richter M,Sporbert A,Purfürst B,Hübner N,Hammes A
Wed Sep 01 00:00:00 EDT 2021
Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion.
Redox biology
Han YK,Kim JS,Lee GB,Lim JH,Park KM
Fri Oct 01 00:00:00 EDT 2021
The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation.
The EMBO journal
Senatore E,Chiuso F,Rinaldi L,Intartaglia D,Delle Donne R,Pedone E,Catalanotti B,Pirone L,Fiorillo B,Moraca F,Giamundo G,Scala G,Raffeiner A,Torres-Quesada O,Stefan E,Kwiatkowski M,van Pijkeren A,Morleo M,Franco B,Garbi C,Conte I,Feliciello A
Mon May 17 00:00:00 EDT 2021
EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis.
Journal of cell science
Partisani M,Baron CL,Ghossoub R,Fayad R,Pagnotta S,Abélanet S,Macia E,Brau F,Lacas-Gervais S,Benmerah A,Luton F,Franco M
Fri Jan 22 00:00:00 EST 2021
EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis.
Journal of cell science
Partisani M,Baron CL,Ghossoub R,Fayad R,Pagnotta S,Abélanet S,Macia E,Brau F,Lacas-Gervais S,Benmerah A,Luton F,Franco M
Fri Jan 22 00:00:00 EST 2021
Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function.
Glia
Cullen CL,O'Rourke M,Beasley SJ,Auderset L,Zhen Y,Pepper RE,Gasperini R,Young KM
Sat May 01 00:00:00 EDT 2021
Δ9-Tetrahydrocannabinol inhibits Hedgehog-dependent patterning during development.
Development (Cambridge, England)
Lo HF,Hong M,Szutorisz H,Hurd YL,Krauss RS
Fri Oct 01 00:00:00 EDT 2021
Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone.
Molecular biology of the cell
Wiegering A,Dildrop R,Vesque C,Khanna H,Schneider-Maunoury S,Gerhardt C
Thu Apr 15 00:00:00 EDT 2021
Xpo7 negatively regulates Hedgehog signaling by exporting Gli2 from the nucleus.
Cellular signalling
Markiewicz Ł,Uśpieński T,Baran B,Niedziółka SM,Niewiadomski P
Thu Apr 01 00:00:00 EDT 2021
Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer.
Scientific reports
Lee J,Park KC,Sul HJ,Hong HJ,Kim KH,Kero J,Shong M
Thu Feb 18 00:00:00 EST 2021
HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells.
Cancers
Shi P,Hoang-Minh LB,Tian J,Cheng A,Basrai R,Kalaria N,Lebowitz JJ,Khoshbouei H,Deleyrolle LP,Sarkisian MR
Thu Apr 01 00:00:00 EDT 2021
HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells.
Cancers
Shi P,Hoang-Minh LB,Tian J,Cheng A,Basrai R,Kalaria N,Lebowitz JJ,Khoshbouei H,Deleyrolle LP,Sarkisian MR
Thu Apr 01 00:00:00 EDT 2021
HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells.
Cancers
Shi P,Hoang-Minh LB,Tian J,Cheng A,Basrai R,Kalaria N,Lebowitz JJ,Khoshbouei H,Deleyrolle LP,Sarkisian MR
Thu Apr 01 00:00:00 EDT 2021
HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells.
Cancers
Shi P,Hoang-Minh LB,Tian J,Cheng A,Basrai R,Kalaria N,Lebowitz JJ,Khoshbouei H,Deleyrolle LP,Sarkisian MR
Thu Apr 01 00:00:00 EDT 2021
Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Han SJ,Kim JI,Lipschutz JH,Park KM
Mon Nov 01 00:00:00 EDT 2021
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
The Journal of cell biology
Zhang YC,Bai YF,Yuan JF,Shen XL,Xu YL,Jian XX,Li S,Song ZQ,Hu HB,Li PY,Tu HQ,Han QY,Wang N,Li AL,Zhang XM,Wu M,Zhou T,Li HY
Mon Feb 01 00:00:00 EST 2021
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
The Journal of cell biology
Zhang YC,Bai YF,Yuan JF,Shen XL,Xu YL,Jian XX,Li S,Song ZQ,Hu HB,Li PY,Tu HQ,Han QY,Wang N,Li AL,Zhang XM,Wu M,Zhou T,Li HY
Mon Feb 01 00:00:00 EST 2021
Cisplatin induces lung cell cilia disruption and lung damage via oxidative stress.
Free radical biology & medicine
Han YK,Kim JS,Jang G,Park KM
Wed Dec 01 00:00:00 EST 2021
Identification of a potent antagonist of smoothened in hedgehog signaling.
Cell & bioscience
Fan J,Li H,Kuang L,Zhao Z,He W,Liu C,Wang Y,Cheng SY,Chen W
Tue Mar 02 00:00:00 EST 2021
Loss of Planar Cell Polarity Effector Fuzzy Causes Renal Hypoplasia by Disrupting Several Signaling Pathways.
Journal of developmental biology
Wang IY,Chung CF,Babayeva S,Sogomonian T,Torban E
Thu Dec 23 00:00:00 EST 2021
Primary Cilia as a Biomarker in Mesenchymal Stem Cells Senescence: Influencing Osteoblastic Differentiation Potency Associated with Hedgehog Signaling Regulation.
Stem cells international
Fu S,Zhang C,Yan X,Li D,Wang Y,Dong C,Cao Z,Ning Y,Shao C,Yang T
Sat Feb 13 00:00:00 EST 2021
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.
Cell reports
Zhang Y,Hao J,Tarrago MG,Warner GM,Giorgadze N,Wei Q,Huang Y,He K,Chen C,Peclat TR,White TA,Ling K,Tchkonia T,Kirkland JL,Chini EN,Hu J
Tue Aug 03 00:00:00 EDT 2021
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution.
Cell
Cowan CS,Renner M,De Gennaro M,Gross-Scherf B,Goldblum D,Hou Y,Munz M,Rodrigues TM,Krol J,Szikra T,Cuttat R,Waldt A,Papasaikas P,Diggelmann R,Patino-Alvarez CP,Galliker P,Spirig SE,Pavlinic D,Gerber-Hollbach N,Schuierer S,Srdanovic A,Balogh M,Panero R,Kusnyerik A,Szabo A,Stadler MB,Orgül S,Picelli S,Hasler PW,Hierlemann A,Scholl HPN,Roma G,Nigsch F,Roska B
Thu Sep 17 00:00:00 EDT 2020
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.
EMBO molecular medicine
Bosakova M,Abraham SP,Nita A,Hruba E,Buchtova M,Taylor SP,Duran I,Martin J,Svozilova K,Barta T,Varecha M,Balek L,Kohoutek J,Radaszkiewicz T,Pusapati GV,Bryja V,Rush ET,Thiffault I,Nickerson DA,Bamshad MJ,Rohatgi R,Cohn DH,Krakow D,Krejci P
Fri Nov 06 00:00:00 EST 2020
ECE2 regulates neurogenesis and neuronal migration during human cortical development.
EMBO reports
Buchsbaum IY,Kielkowski P,Giorgio G,O'Neill AC,Di Giaimo R,Kyrousi C,Khattak S,Sieber SA,Robertson SP,Cappello S
Wed May 06 00:00:00 EDT 2020
Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa.
Frontiers in cell and developmental biology
Gao ML,Lei XL,Han F,He KW,Jin SQ,Zhang YY,Jin ZB
Mon Sep 28 00:00:00 EDT 2020
Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1.
Frontiers in cell and developmental biology
Zhang C,Li C,Siu GKY,Luo X,Yu S
Mon Sep 28 00:00:00 EDT 2020
CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure (London, England : 1993)
Ochi T,Quarantotti V,Lin H,Jullien J,Rosa E Silva I,Boselli F,Barnabas DD,Johnson CM,McLaughlin SH,Freund SMV,Blackford AN,Kimata Y,Goldstein RE,Jackson SP,Blundell TL,Dutcher SK,Gergely F,van Breugel M
Tue Jun 02 00:00:00 EDT 2020
DIAPH1 regulates ciliogenesis and trafficking in primary cilia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Palander O,Trimble WS
Tue Dec 01 00:00:00 EST 2020
Ciliary proteins specify the cell inflammatory response by tuning NFκB signalling, independently of primary cilia.
Journal of cell science
Mc Fie M,Koneva L,Collins I,Coveney CR,Clube AM,Chanalaris A,Vincent TL,Bezbradica JS,Sansom SN,Wann AKT
Wed Jul 08 00:00:00 EDT 2020
Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny.
Human molecular genetics
Gilet JG,Ivanova EL,Trofimova D,Rudolf G,Meziane H,Broix L,Drouot N,Courraud J,Skory V,Voulleminot P,Osipenko M,Bahi-Buisson N,Yalcin B,Birling MC,Hinckelmann MV,Kwok BH,Allingham JS,Chelly J
Fri Mar 27 00:00:00 EDT 2020
The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.
Human molecular genetics
Shohayeb B,Ho U,Yeap YY,Parton RG,Millard SS,Xu Z,Piper M,Ng DCH
Wed Jan 15 00:00:00 EST 2020
An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration.
Molecular biology of the cell
Su S,Begum S,Ezratty EJ
Sat Aug 01 00:00:00 EDT 2020
Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex.
Neuron
Xing L,Kalebic N,Namba T,Vaid S,Wimberger P,Huttner WB
Wed Dec 23 00:00:00 EST 2020
Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control.
Current biology : CB
Ho EK,Tsai AE,Stearns T
Mon Jul 20 00:00:00 EDT 2020
Primary cilia mediate parathyroid hormone receptor type 1 osteogenic actions in osteocytes and osteoblasts via Gli activation.
Journal of cellular physiology
Martín-Guerrero E,Tirado-Cabrera I,Buendía I,Alonso V,Gortázar AR,Ardura JA
Thu Oct 01 00:00:00 EDT 2020
Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes.
Journal of neuroscience research
La Sala G,Di Pietro C,Matteoni R,Bolasco G,Marazziti D,Tocchini-Valentini GP
Thu Dec 17 00:00:00 EST 2020
MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity.
JCI insight
Pottorf TS,Fagan MP,Burkey BF,Cho DJ,Vath JE,Tran PV
Thu Jan 30 00:00:00 EST 2020
Intracellular calcium response of primary cilia of tubular cells to modulated shear stress under oxidative stress.
Biomicrofluidics
Chikamori M,Kimura H,Inagi R,Zhou J,Nangaku M,Fujii T
Wed Jul 01 00:00:00 EDT 2020
Primary cilia mediate Klf2-dependant Notch activation in regenerating heart.
Protein & cell
Li X,Lu Q,Peng Y,Geng F,Shao X,Zhou H,Cao Y,Zhang R
Mon Jun 01 00:00:00 EDT 2020
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
The EMBO journal
Miyamoto T,Hosoba K,Itabashi T,Iwane AH,Akutsu SN,Ochiai H,Saito Y,Yamamoto T,Matsuura S
Wed Jun 17 00:00:00 EDT 2020
Pannexin-1 mediates fluid shear stress-sensitive purinergic signaling and cyst growth in polycystic kidney disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Verschuren EHJ,Rigalli JP,Castenmiller C,Rohrbach MU,Bindels RJM,Peters DJM,Arjona FJ,Hoenderop JGJ
Fri May 01 00:00:00 EDT 2020
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division.
Nature communications
Bonucci M,Kuperwasser N,Barbe S,Koka V,de Villeneuve D,Zhang C,Srivastava N,Jia X,Stokes MP,Bienaimé F,Verkarre V,Lopez JB,Jaulin F,Pontoglio M,Terzi F,Delaval B,Piel M,Pende M
Wed Jun 24 00:00:00 EDT 2020
Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2.
eLife
Tona Y,Wu DK
Wed Sep 23 00:00:00 EDT 2020
Characterization of primary cilia features reveal cell-type specific variability in in vitro models of osteogenic and chondrogenic differentiation.
PeerJ
Upadhyai P,Guleria VS,Udupa P
Mon Sep 28 00:00:00 EDT 2020
Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang W,Allard BA,Pottorf TS,Wang HH,Vivian JL,Tran PV
Fri May 01 00:00:00 EDT 2020
The HOPS complex subunit VPS39 controls ciliogenesis through autophagy.
Human molecular genetics
Iaconis D,Crina C,Brillante S,Indrieri A,Morleo M,Franco B
Wed Apr 15 00:00:00 EDT 2020
A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice.
Disease models & mechanisms
Abdelhamed Z,Lukacs M,Cindric S,Ali S,Omran H,Stottmann RW
Fri Oct 30 00:00:00 EDT 2020
Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.
Developmental biology
Fulmer D,Toomer KA,Glover J,Guo L,Moore K,Moore R,Stairley R,Gensemer C,Abrol S,Rumph MK,Emetu F,Lipschutz JH,McDowell C,Bian J,Wang C,Beck T,Wessels A,Renault MA,Norris RA
Wed Jul 01 00:00:00 EDT 2020
Loss of Cilia Does Not Slow Liver Disease Progression in Mouse Models of Autosomal Recessive Polycystic Kidney Disease.
Kidney360
Gallagher AR,Somlo S
Thu Sep 24 00:00:00 EDT 2020
Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells.
Frontiers in cell and developmental biology
Townshend RF,Shao Y,Wang S,Cortez CL,Esfahani SN,Spence JR,O'Shea KS,Fu J,Gumucio DL,Taniguchi K
Sat Nov 14 00:00:00 EST 2020
An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics.
Scientific reports
Zalenski AA,Majumder S,De K,Venere M
Tue Aug 18 00:00:00 EDT 2020
Mosaic Analysis with Double Markers reveals IGF1R function in granule cell progenitors during cerebellar development.
Developmental biology
Terry TT,Cheng T,Mahjoub M,Zong H
Tue Sep 15 00:00:00 EDT 2020
TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons.
eLife
Bowie E,Goetz SC
Tue Jan 14 00:00:00 EST 2020
CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation.
EMBO reports
Ki SM,Kim JH,Won SY,Oh SJ,Lee IY,Bae YK,Chung KW,Choi BO,Park B,Choi EJ,Lee JE
Wed Feb 05 00:00:00 EST 2020
The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis.
Bioscience reports
Li ZZ,Zhao WL,Wang GS,Gu NH,Sun F
Fri Jan 31 00:00:00 EST 2020
NRF2 negatively regulates primary ciliogenesis and hedgehog signaling.
PLoS biology
Liu P,Dodson M,Fang D,Chapman E,Zhang DD
Sat Feb 01 00:00:00 EST 2020
NRF2 negatively regulates primary ciliogenesis and hedgehog signaling.
PLoS biology
Liu P,Dodson M,Fang D,Chapman E,Zhang DD
Sat Feb 01 00:00:00 EST 2020
Sonic hedgehog signalling as a potential endobronchial biomarker in COPD.
Respiratory research
Ancel J,Belgacemi R,Perotin JM,Diabasana Z,Dury S,Dewolf M,Bonnomet A,Lalun N,Birembaut P,Polette M,Deslée G,Dormoy V
Fri Aug 07 00:00:00 EDT 2020
CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells.
Frontiers in cell and developmental biology
Kobayashi T,Tanaka K,Mashima Y,Shoda A,Tokuda M,Itoh H
Tue Dec 01 00:00:00 EST 2020
Differentiation of ciliated human midbrain-derived LUHMES neurons.
Journal of cell science
Lauter G,Coschiera A,Yoshihara M,Sugiaman-Trapman D,Ezer S,Sethurathinam S,Katayama S,Kere J,Swoboda P
Mon Nov 09 00:00:00 EST 2020
hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning.
Biology of the cell
Pizon V,Gaudin N,Poteau M,Cifuentes-Diaz C,Demdou R,Heyer V,Reina San Martin B,Azimzadeh J
Wed Jan 01 00:00:00 EST 2020
Nubp2 is required for cranial neural crest survival in the mouse.
Developmental biology
DiStasio A,Paulding D,Chaturvedi P,Stottmann RW
Sat Feb 15 00:00:00 EST 2020
Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function.
Human molecular genetics
Flynn M,Whitton L,Donohoe G,Morrison CG,Morris DW
Sat Feb 01 00:00:00 EST 2020
A reduction of primary cilia but not hedgehog signaling disrupts morphogenesis in testicular organoids.
Cell and tissue research
Goldsmith TM,Sakib S,Webster D,Carlson DF,Van der Hoorn F,Dobrinski I
Wed Apr 01 00:00:00 EDT 2020
Polycystin-1 regulates ARHGAP35-dependent centrosomal RhoA activation and ROCK signaling.
JCI insight
Streets AJ,Prosseda PP,Ong AC
Thu Aug 20 00:00:00 EDT 2020
ARL13B regulates Sonic hedgehog signaling from outside primary cilia.
eLife
Gigante ED,Taylor MR,Ivanova AA,Kahn RA,Caspary T
Wed Mar 04 00:00:00 EST 2020
The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis.
eLife
Yoshida S,Aoki K,Fujiwara K,Nakakura T,Kawamura A,Yamada K,Ono M,Yogosawa S,Yoshida K
Thu Aug 06 00:00:00 EDT 2020
The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis.
eLife
Yoshida S,Aoki K,Fujiwara K,Nakakura T,Kawamura A,Yamada K,Ono M,Yogosawa S,Yoshida K
Thu Aug 06 00:00:00 EDT 2020
Roles of TOG and jelly-roll domains of centrosomal protein CEP104 in its functions in cilium elongation and Hedgehog signaling.
The Journal of biological chemistry
Yamazoe T,Nagai T,Umeda S,Sugaya Y,Mizuno K
Fri Oct 23 00:00:00 EDT 2020
Robust classification of cell cycle phase and biological feature extraction by image-based deep learning.
Molecular biology of the cell
Nagao Y,Sakamoto M,Chinen T,Okada Y,Takao D
Mon Jun 15 00:00:00 EDT 2020
Primary Ciliary Deficits in the Dentate Gyrus of Fragile X Syndrome.
Stem cell reports
Lee B,Panda S,Lee HY
Tue Aug 11 00:00:00 EDT 2020
Analysis of Caveolin in Primary Cilia.
Methods in molecular biology (Clifton, N.J.)
Morthorst SK,Mogensen JB,Christensen ST,Pedersen LB
Wed Mar 31 00:00:00 EDT 2021
The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts.
BMC molecular and cell biology
Venugopal N,Ghosh A,Gala H,Aloysius A,Vyas N,Dhawan J
Wed Apr 15 00:00:00 EDT 2020
Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis.
The Journal of cell biology
Viol L,Hata S,Pastor-Peidro A,Neuner A,Murke F,Wuchter P,Ho AD,Giebel B,Pereira G
Mon Mar 02 00:00:00 EST 2020
Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation.
Molecular vision
Chen HY,Kaya KD,Dong L,Swaroop A
Fri Mar 06 00:00:00 EST 2020
Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation.
Molecular vision
Chen HY,Kaya KD,Dong L,Swaroop A
Fri Mar 06 00:00:00 EST 2020
Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals.
Acta neuropathologica communications
Findakly S,Choudhury A,Daggubati V,Pekmezci M,Lang UE,Raleigh DR
Mon Jul 20 00:00:00 EDT 2020
Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Nature communications
Kim Y,Lee J,Seppala M,Cobourne MT,Kim SH
Fri Apr 24 00:00:00 EDT 2020
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium.
eLife
Hansen JN,Kaiser F,Klausen C,Stüven B,Chong R,Bönigk W,Mick DU,Möglich A,Jurisch-Yaksi N,Schmidt FI,Wachten D
Wed Jun 24 00:00:00 EDT 2020
Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts.
Scientific reports
Jühlen R,Martinelli V,Vinci C,Breckpot J,Fahrenkrog B
Mon Nov 09 00:00:00 EST 2020
Epb41l5 interacts with Iqcb1 and regulates ciliary function in zebrafish embryos.
Journal of cell science
Yu T,Matsuda M
Sun Jun 28 00:00:00 EDT 2020
Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly.
Journal of cell science
Lin YN,Lee YS,Li SK,Tang TK
Wed Jun 24 00:00:00 EDT 2020
Protein phosphatase 1 regulatory subunit 35 is required for ciliogenesis, notochord morphogenesis, and cell-cycle progression during murine development.
Developmental biology
Archambault D,Cheong A,Iverson E,Tremblay KD,Mager J
Tue Sep 01 00:00:00 EDT 2020
Primary cilium remodeling mediates a cell signaling switch in differentiating neurons.
Science advances
Toro-Tapia G,Das RM
Fri May 01 00:00:00 EDT 2020
PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress.
Nature communications
Boukhalfa A,Nascimbeni AC,Ramel D,Dupont N,Hirsch E,Gayral S,Laffargue M,Codogno P,Morel E
Wed Jan 15 00:00:00 EST 2020
Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway.
Life science alliance
Gerakopoulos V,Ngo P,Tsiokas L
Tue Sep 01 00:00:00 EDT 2020
Mutations in the exocyst component EXOC2 cause severe defects in human brain development.
The Journal of experimental medicine
Van Bergen NJ,Ahmed SM,Collins F,Cowley M,Vetro A,Dale RC,Hock DH,de Caestecker C,Menezes M,Massey S,Ho G,Pisano T,Glover S,Gusman J,Stroud DA,Dinger M,Guerrini R,Macara IG,Christodoulou J
Mon Oct 05 00:00:00 EDT 2020
CENPV Is a CYLD-Interacting Molecule Regulating Ciliary Acetylated α-Tubulin.
The Journal of investigative dermatology
Chiticariu E,Regamey A,Huber M,Hohl D
Wed Jan 01 00:00:00 EST 2020
FOP Negatively Regulates Ciliogenesis and Promotes Cell Cycle Re-entry by Facilitating Primary Cilia Disassembly.
Frontiers in cell and developmental biology
Jiang H,Liu S,Cheung MH,Amin A,Liang C
Sat Dec 12 00:00:00 EST 2020
A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells.
Science advances
Dias JM,Alekseenko Z,Jeggari A,Boareto M,Vollmer J,Kozhevnikova M,Wang H,Matise MP,Alexeyenko A,Iber D,Ericson J
Tue Sep 01 00:00:00 EDT 2020
Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3.
The Journal of biological chemistry
Jászai J,Thamm K,Karbanová J,Janich P,Fargeas CA,Huttner WB,Corbeil D
Fri May 01 00:00:00 EDT 2020
Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3.
The Journal of biological chemistry
Jászai J,Thamm K,Karbanová J,Janich P,Fargeas CA,Huttner WB,Corbeil D
Fri May 01 00:00:00 EDT 2020
Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3.
The Journal of biological chemistry
Jászai J,Thamm K,Karbanová J,Janich P,Fargeas CA,Huttner WB,Corbeil D
Fri May 01 00:00:00 EDT 2020
Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3.
The Journal of biological chemistry
Jászai J,Thamm K,Karbanová J,Janich P,Fargeas CA,Huttner WB,Corbeil D
Fri May 01 00:00:00 EDT 2020
Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia.
Developmental cell
Nguyen QPH,Liu Z,Albulescu A,Ouyang H,Zlock L,Coyaud E,Laurent E,Finkbeiner W,Moraes TJ,Raught B,Mennella V
Mon Oct 26 00:00:00 EDT 2020
TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating.
Nature communications
Yan H,Chen C,Chen H,Hong H,Huang Y,Ling K,Hu J,Wei Q
Mon May 04 00:00:00 EDT 2020
A novel CDK-independent function of p27Kip1 in preciliary vesicle trafficking during ciliogenesis.
Biochemical and biophysical research communications
Yukimoto H,Miyamoto T,Kiyono T,Wang S,Matsuura S,Mizoguchi A,Katayama N,Inagaki M,Kasahara K
Tue Jun 30 00:00:00 EDT 2020
Use of patient derived urine renal epithelial cells to confirm pathogenicity of PKHD1 alleles.
BMC nephrology
Molinari E,Srivastava S,Dewhurst RM,Sayer JA
Thu Oct 15 00:00:00 EDT 2020
Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus.
Nature communications
Lee CH,Song DK,Park CB,Choi J,Kang GM,Shin SH,Kwon I,Park S,Kim S,Kim JY,Dugu H,Park JW,Choi JH,Min SH,Sohn JW,Kim MS
Fri Nov 13 00:00:00 EST 2020
Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD.
EBioMedicine
Belgacemi R,Luczka E,Ancel J,Diabasana Z,Perotin JM,Germain A,Lalun N,Birembaut P,Dubernard X,Mérol JC,Delepine G,Polette M,Deslée G,Dormoy V
Wed Jan 01 00:00:00 EST 2020
Functional Alterations in Ciliogenesis-Associated Kinase 1 (CILK1) that Result from Mutations Linked to Juvenile Myoclonic Epilepsy.
Cells
Wang EJ,Gailey CD,Brautigan DL,Fu Z
Thu Mar 12 00:00:00 EDT 2020
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
The Journal of cell biology
Desai PB,Stuck MW,Lv B,Pazour GJ
Mon Jul 06 00:00:00 EDT 2020
Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse.
Disease models & mechanisms
Bangs FK,Miller P,O'Neill E
Thu Jul 30 00:00:00 EDT 2020
LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation.
Human molecular genetics
Christ A,Marczenke M,Willnow TE
Wed Nov 25 00:00:00 EST 2020
Profilin1-Dependent F-Actin Assembly Controls Division of Apical Radial Glia and Neocortex Development.
Cerebral cortex (New York, N.Y. : 1991)
Kullmann JA,Meyer S,Pipicelli F,Kyrousi C,Schneider F,Bartels N,Cappello S,Rust MB
Mon May 18 00:00:00 EDT 2020
Intraflagellar-transport A dysfunction causes hyperphagia-induced systemic insulin resistance in a pre-obese state.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jacobs DT,Allard BA,Pottorf TS,Silva LM,Wang W,Al-Naamani A,Agborbesong E,Wang T,Carr DA,Tran PV
Wed Jan 01 00:00:00 EST 2020
ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jung E,Choi TI,Lee JE,Kim CH,Kim J
Wed Jan 01 00:00:00 EST 2020
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics.
The EMBO journal
Singer D,Thamm K,Zhuang H,Karbanová J,Gao Y,Walker JV,Jin H,Wu X,Coveney CR,Marangoni P,Lu D,Grayson PRC,Gulsen T,Liu KJ,Ardu S,Wann AK,Luo S,Zambon AC,Jetten AM,Tredwin C,Klein OD,Attanasio M,Carmeliet P,Huttner WB,Corbeil D,Hu B
Tue Jan 15 00:00:00 EST 2019
Unexpected Activities in Regulating Ciliation Contribute to Off-target Effects of Targeted Drugs.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kiseleva AA,Korobeynikov VA,Nikonova AS,Zhang P,Makhov P,Deneka AY,Einarson MB,Serebriiskii IG,Liu H,Peterson JR,Golemis EA
Mon Jul 01 00:00:00 EDT 2019
Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.
Proceedings of the National Academy of Sciences of the United States of America
Kunova Bosakova M,Nita A,Gregor T,Varecha M,Gudernova I,Fafilek B,Barta T,Basheer N,Abraham SP,Balek L,Tomanova M,Fialova Kucerova J,Bosak J,Potesil D,Zieba J,Song J,Konik P,Park S,Duran I,Zdrahal Z,Smajs D,Jansen G,Fu Z,Ko HW,Hampl A,Trantirek L,Krakow D,Krejci P
Tue Mar 05 00:00:00 EST 2019
Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation.
Cellular and molecular life sciences : CMLS
Patnaik SR,Kretschmer V,Brücker L,Schneider S,Volz AK,Oancea-Castillo LDR,May-Simera HL
Fri Feb 01 00:00:00 EST 2019
Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation.
Cellular and molecular life sciences : CMLS
Patnaik SR,Kretschmer V,Brücker L,Schneider S,Volz AK,Oancea-Castillo LDR,May-Simera HL
Fri Feb 01 00:00:00 EST 2019
Indian Hedgehog links obesity to development of hepatocellular carcinoma.
Oncogene
Chong YC,Lim TE,Fu Y,Shin EM,Tergaonkar V,Han W
Fri Mar 01 00:00:00 EST 2019
Indian Hedgehog links obesity to development of hepatocellular carcinoma.
Oncogene
Chong YC,Lim TE,Fu Y,Shin EM,Tergaonkar V,Han W
Fri Mar 01 00:00:00 EST 2019
Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants.
Genes & diseases
Kane MS,Diamonstein CJ,Hauser N,Deeken JF,Niederhuber JE,Vilboux T
Fri Mar 01 00:00:00 EST 2019
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.
Development (Cambridge, England)
Capowski EE,Samimi K,Mayerl SJ,Phillips MJ,Pinilla I,Howden SE,Saha J,Jansen AD,Edwards KL,Jager LD,Barlow K,Valiauga R,Erlichman Z,Hagstrom A,Sinha D,Sluch VM,Chamling X,Zack DJ,Skala MC,Gamm DM
Wed Jan 09 00:00:00 EST 2019
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.
Development (Cambridge, England)
Capowski EE,Samimi K,Mayerl SJ,Phillips MJ,Pinilla I,Howden SE,Saha J,Jansen AD,Edwards KL,Jager LD,Barlow K,Valiauga R,Erlichman Z,Hagstrom A,Sinha D,Sluch VM,Chamling X,Zack DJ,Skala MC,Gamm DM
Wed Jan 09 00:00:00 EST 2019
Chloroquine inhibits human retina pigmented epithelial cell growth and microtubule nucleation by downregulating p150glued.
Journal of cellular physiology
Chen TY,Lien WC,Cheng HL,Kuan TS,Sheu SY,Wang CY
Mon Jul 01 00:00:00 EDT 2019
Chloroquine inhibits human retina pigmented epithelial cell growth and microtubule nucleation by downregulating p150glued.
Journal of cellular physiology
Chen TY,Lien WC,Cheng HL,Kuan TS,Sheu SY,Wang CY
Mon Jul 01 00:00:00 EDT 2019
Tubular flow activates magnesium transport in the distal convoluted tubule.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Verschuren EHJ,Hoenderop JGJ,Peters DJM,Arjona FJ,Bindels RJM
Mon Apr 01 00:00:00 EDT 2019
The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling.
Human molecular genetics
Massa F,Tammaro R,Prado MA,Cesana M,Lee BH,Finley D,Franco B,Morleo M
Fri Mar 01 00:00:00 EST 2019
The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling.
Human molecular genetics
Massa F,Tammaro R,Prado MA,Cesana M,Lee BH,Finley D,Franco B,Morleo M
Fri Mar 01 00:00:00 EST 2019
RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits.
Human molecular genetics
Lara Ordónez AJ,Fernández B,Fdez E,Romo-Lozano M,Madero-Pérez J,Lobbestael E,Baekelandt V,Aiastui A,López de Munaín A,Melrose HL,Civiero L,Hilfiker S
Fri Nov 01 00:00:00 EDT 2019
Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion.
Human molecular genetics
Dupont MA,Humbert C,Huber C,Siour Q,Guerrera IC,Jung V,Christensen A,Pouliet A,Garfa-Traoré M,Nitschké P,Injeyan M,Millar K,Chitayat D,Shannon P,Girisha KM,Shukla A,Mechler C,Lorentzen E,Benmerah A,Cormier-Daire V,Jeanpierre C,Saunier S,Delous M
Thu Aug 15 00:00:00 EDT 2019
Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl-]i in mouse airway cilia.
Pflugers Archiv : European journal of physiology
Ikeuchi Y,Kogiso H,Hosogi S,Tanaka S,Shimamoto C,Matsumura H,Inui T,Marunaka Y,Nakahari T
Fri Feb 01 00:00:00 EST 2019
Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl-]i in mouse airway cilia.
Pflugers Archiv : European journal of physiology
Ikeuchi Y,Kogiso H,Hosogi S,Tanaka S,Shimamoto C,Matsumura H,Inui T,Marunaka Y,Nakahari T
Fri Feb 01 00:00:00 EST 2019
HDAC3 and HDAC8 are required for cilia assembly and elongation.
Biology open
Park SA,Yoo H,Seol JH,Rhee K
Fri Aug 09 00:00:00 EDT 2019
Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Respiratory research
Wang G,Lou HH,Salit J,Leopold PL,Driscoll S,Schymeinsky J,Quast K,Visvanathan S,Fine JS,Thomas MJ,Crystal RG
Fri Aug 23 00:00:00 EDT 2019
Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse.
eLife
Portal C,Rompolas P,Lwigale P,Iomini C
Tue Dec 17 00:00:00 EST 2019
Hydrocephalus in a rat model of Meckel Gruber syndrome with a TMEM67 mutation.
Scientific reports
Shim JW,Territo PR,Simpson S,Watson JC,Jiang L,Riley AA,McCarthy B,Persohn S,Fulkerson D,Blazer-Yost BL
Thu Jan 31 00:00:00 EST 2019
Silencing Y-box binding protein-1 inhibits triple-negative breast cancer cell invasiveness via regulation of MMP1 and beta-catenin expression.
Cancer letters
Lim JP,Nair S,Shyamasundar S,Chua PJ,Muniasamy U,Matsumoto K,Gunaratne J,Bay BH
Fri Jun 28 00:00:00 EDT 2019
Ocular Ciliopathies: Genetic and Mechanistic Insights into Developing Therapies.
Current medicinal chemistry
Shivanna M,Anand M,Chakrabarti S,Khanna H
Wed Oct 23 00:00:00 EDT 2019
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Oncogenesis
Spiombi E,Angrisani A,Fonte S,De Feudis G,Fabretti F,Cucchi D,Izzo M,Infante P,Miele E,Po A,Di Magno L,Magliozzi R,Guardavaccaro D,Maroder M,Canettieri G,Giannini G,Ferretti E,Gulino A,Di Marcotullio L,Moretti M,De Smaele E
Mon Nov 04 00:00:00 EST 2019
Neutrophil gelatinase-associated lipocalin (NGAL) is localised to the primary cilium in renal tubular epithelial cells - A novel source of urinary biomarkers of renal injury.
Biochimica et biophysica acta. Molecular basis of disease
Cassidy H,Slyne J,Higgins M,Radford R,Conlon PJ,Watson AJ,Ryan MP,McMorrow T,Slattery C
Sun Dec 01 00:00:00 EST 2019
HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development.
Neuron
Tang T,Zhang Y,Wang Y,Cai Z,Lu Z,Li L,Huang R,Hagelkruys A,Matthias P,Zhang H,Seiser C,Xie Y
Wed Mar 20 00:00:00 EDT 2019
Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region.
Scientific reports
Izumi H,Li Y,Shibaki M,Mori D,Yasunami M,Sato S,Matsunaga H,Mae T,Kodama K,Kamijo T,Kaneko Y,Nakagawara A
Tue Feb 19 00:00:00 EST 2019
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Scientific reports
Molinari E,Ramsbottom SA,Srivastava S,Booth P,Alkanderi S,McLafferty SM,Devlin LA,White K,Gunay-Aygun M,Miles CG,Sayer JA
Thu Jul 25 00:00:00 EDT 2019
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Scientific reports
Molinari E,Ramsbottom SA,Srivastava S,Booth P,Alkanderi S,McLafferty SM,Devlin LA,White K,Gunay-Aygun M,Miles CG,Sayer JA
Thu Jul 25 00:00:00 EDT 2019
Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation.
Osteoarthritis and cartilage
Fu S,Thompson CL,Ali A,Wang W,Chapple JP,Mitchison HM,Beales PL,Wann AKT,Knight MM
Mon Jul 01 00:00:00 EDT 2019
Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development.
Frontiers in cell and developmental biology
Pruski M,Hu L,Yang C,Wang Y,Zhang JB,Zhang L,Huang Y,Rajnicek AM,St Clair D,McCaig CD,Lang B,Ding YQ
Thu Oct 01 00:00:00 EDT 2020
Induction of Neural Crest Stem Cells From Bardet-Biedl Syndrome Patient Derived hiPSCs.
Frontiers in molecular neuroscience
Barrell WB,Griffin JN,Harvey JL,Danovi D,Beales P,Grigoriadis AE,Liu KJ
Wed Aug 23 00:00:00 EDT 2023
Primary Cilia Exhibit Mechanosensitivity to Cyclic Tensile Strain and Lineage-Dependent Expression in Adipose-Derived Stem Cells.
Scientific reports
Bodle J,Hamouda MS,Cai S,Williams RB,Bernacki SH,Loboa EG
Wed May 29 00:00:00 EDT 2019
Elevated miR-200a and miR-141 inhibit endocrine gland-derived vascular endothelial growth factor expression and ciliogenesis in preeclampsia.
The Journal of physiology
Wang CY,Tsai PY,Chen TY,Tsai HL,Kuo PL,Su MT
Sat Jun 01 00:00:00 EDT 2019
The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.
Journal of the American Society of Nephrology : JASN
Ignarski M,Rill C,Kaiser RWJ,Kaldirim M,Neuhaus R,Esmaillie R,Li X,Klein C,Bohl K,Petersen M,Frese CK,Höhne M,Atanassov I,Rinschen MM,Höpker K,Schermer B,Benzing T,Dieterich C,Fabretti F,Müller RU
Mon Apr 01 00:00:00 EDT 2019
661W Photoreceptor Cell Line as a Cell Model for Studying Retinal Ciliopathies.
Frontiers in genetics
Wheway G,Nazlamova L,Turner D,Cross S
Thu Oct 01 00:00:00 EDT 2020
Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson's disease model.
Cell death & disease
Bae JE,Kang GM,Min SH,Jo DS,Jung YK,Kim K,Kim MS,Cho DH
Mon Dec 16 00:00:00 EST 2019
Fbxo41 Promotes Disassembly of Neuronal Primary Cilia.
Scientific reports
King CR,A A Quadros AR,Chazeau A,Saarloos I,van der Graaf AJ,Verhage M,Toonen RF
Mon Jun 03 00:00:00 EDT 2019
Differential requirements for the EF-hand domains of human centrin 2 in primary ciliogenesis and nucleotide excision repair.
Journal of cell science
Khouj EM,Prosser SL,Tada H,Chong WM,Liao JC,Sugasawa K,Morrison CG
Thu Oct 03 00:00:00 EDT 2019
Restoration of primary cilia in obese adipose-derived mesenchymal stem cells by inhibiting Aurora A or extracellular signal-regulated kinase.
Stem cell research & therapy
Ritter A,Kreis NN,Roth S,Friemel A,Jennewein L,Eichbaum C,Solbach C,Louwen F,Yuan J
Wed Aug 14 00:00:00 EDT 2019
Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish.
Communications biology
Maerz LD,Burkhalter MD,Schilpp C,Wittekindt OH,Frick M,Philipp M
Thu Apr 02 00:00:00 EDT 2020
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling.
Cell reports
Frikstad KM,Molinari E,Thoresen M,Ramsbottom SA,Hughes F,Letteboer SJF,Gilani S,Schink KO,Stokke T,Geimer S,Pedersen LB,Giles RH,Akhmanova A,Roepman R,Sayer JA,Patzke S
Tue Aug 13 00:00:00 EDT 2019
Centrosome-derived microtubule radial array, PCM-1 protein, and primary cilia formation.
Protoplasma
Fokin Artem I,Zhapparova Olga N,Burakov Anton V,Nadezhdina Elena S
Sun Sep 01 00:00:00 EDT 2019
CCDC114 is mutated in patient with a complex phenotype combining primary ciliary dyskinesia, sensorineural deafness, and renal disease.
Journal of human genetics
Li P,He Y,Cai G,Xiao F,Yang J,Li Q,Chen X
Tue Jan 01 00:00:00 EST 2019
Characterization of Functional Primary Cilia in Human Induced Pluripotent Stem Cell-Derived Neurons.
Neurochemical research
Miki D,Kobayashi Y,Okada T,Miyamoto T,Takei N,Sekino Y,Koganezawa N,Shirao T,Saito Y
Mon Jul 01 00:00:00 EDT 2019
microRNAs Regulating Human and Mouse Naïve Pluripotency.
International journal of molecular sciences
Wang Y,Hussein AM,Somasundaram L,Sankar R,Detraux D,Mathieu J,Ruohola-Baker H
Fri Nov 22 00:00:00 EST 2019
Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding.
PLoS biology
Mirvis M,Siemers KA,Nelson WJ,Stearns TP
Mon Jul 01 00:00:00 EDT 2019
A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia.
Human molecular genetics
Cheong A,Degani R,Tremblay KD,Mager J
Thu Aug 15 00:00:00 EDT 2019
Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine.
Redox biology
Kong MJ,Bak SH,Han KH,Kim JI,Park JW,Park KM
Tue Jan 01 00:00:00 EST 2019
Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine.
Redox biology
Kong MJ,Bak SH,Han KH,Kim JI,Park JW,Park KM
Tue Jan 01 00:00:00 EST 2019
Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine.
Redox biology
Kong MJ,Bak SH,Han KH,Kim JI,Park JW,Park KM
Tue Jan 01 00:00:00 EST 2019
Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine.
Redox biology
Kong MJ,Bak SH,Han KH,Kim JI,Park JW,Park KM
Tue Jan 01 00:00:00 EST 2019
Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade.
eLife
Lodge EJ,Santambrogio A,Russell JP,Xekouki P,Jacques TS,Johnson RL,Thavaraj S,Bornstein SR,Andoniadou CL
Tue Mar 26 00:00:00 EDT 2019
Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis.
Annals of neurology
Hong H,Joo K,Park SM,Seo J,Kim MH,Shin E,Cheong HI,Lee JH,Kim J
Mon Jul 01 00:00:00 EDT 2019
Rab7 regulates primary cilia disassembly through cilia excision.
The Journal of cell biology
Wang G,Hu HB,Chang Y,Huang Y,Song ZQ,Zhou SB,Chen L,Zhang YC,Wu M,Tu HQ,Yuan JF,Wang N,Pan X,Li AL,Zhou T,Zhang XM,He K,Li HY
Mon Dec 02 00:00:00 EST 2019
Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes.
Scientific reports
Bae JE,Choi H,Shin DW,Na HW,Park NY,Kim JB,Jo DS,Cho MJ,Lyu JH,Chang JH,Lee EH,Lee TR,Kim HJ,Cho DH
Fri Mar 08 00:00:00 EST 2019
Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Cell
Hilgendorf KI,Johnson CT,Mezger A,Rice SL,Norris AM,Demeter J,Greenleaf WJ,Reiter JF,Kopinke D,Jackson PK
Wed Nov 27 00:00:00 EST 2019
Mutations in ARL2BP, a protein required for ciliary microtubule structure, cause syndromic male infertility in humans and mice.
PLoS genetics
Moye AR,Bedoni N,Cunningham JG,Sanzhaeva U,Tucker ES,Mathers P,Peter VG,Quinodoz M,Paris LP,Coutinho-Santos L,Camacho P,Purcell MG,Winkelmann AC,Foster JA,Pugacheva EN,Rivolta C,Ramamurthy V
Thu Aug 01 00:00:00 EDT 2019
A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma.
Cancers
White CL,Jayasekara WSN,Picard D,Chen J,Watkins DN,Cain JE,Remke M,Gough DJ
Fri Nov 01 00:00:00 EDT 2019
CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis.
Scientific reports
Tsai JJ,Hsu WB,Liu JH,Chang CW,Tang TK
Mon Apr 15 00:00:00 EDT 2019
Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis.
Cells
Oh YS,Wang EJ,Gailey CD,Brautigan DL,Allen BL,Fu Z
Thu Jul 04 00:00:00 EDT 2019
Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of Intraflagellar Transport in Mammalian Cilia.
Current biology : CB
Engelke MF,Waas B,Kearns SE,Suber A,Boss A,Allen BL,Verhey KJ
Mon Apr 01 00:00:00 EDT 2019
Integrated miRNA and mRNA expression profiling identifies novel targets and pathological mechanisms in autoimmune thyroid diseases.
EBioMedicine
Martínez-Hernández R,Serrano-Somavilla A,Ramos-Leví A,Sampedro-Nuñez M,Lens-Pardo A,Muñoz De Nova JL,Triviño JC,González MU,Torné L,Casares-Arias J,Martín-Cófreces NB,Sánchez-Madrid F,Marazuela M
Sun Dec 01 00:00:00 EST 2019
AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/- iPSC-Derived RPE Cells.
Molecular therapy. Methods & clinical development
Brydon EM,Bronstein R,Buskin A,Lako M,Pierce EA,Fernandez-Godino R
Fri Dec 13 00:00:00 EST 2019
The ciliary GTPase Arl3 maintains tissue architecture by directing planar spindle orientation during epidermal morphogenesis.
Development (Cambridge, England)
Bhattarai SR,Begum S,Popow R,Ezratty EJ
Fri May 10 00:00:00 EDT 2019
Loss of Primary Cilia Results in the Development of Cancer in the Murine Thyroid Gland.
Molecules and cells
Lee J,Yi S,Chang JY,Kim JT,Sul HJ,Park KC,Zhu X,Cheng SY,Kero J,Kim J,Shong M
Thu Feb 28 00:00:00 EST 2019
Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans.
Cell reports
Kluth O,Stadion M,Gottmann P,Aga H,Jähnert M,Scherneck S,Vogel H,Krus U,Seelig A,Ling C,Gerdes J,Schürmann A
Tue Mar 12 00:00:00 EDT 2019
Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening.
Nature communications
Kim M,Mun H,Sung CO,Cho EJ,Jeon HJ,Chun SM,Jung DJ,Shin TH,Jeong GS,Kim DK,Choi EK,Jeong SY,Taylor AM,Jain S,Meyerson M,Jang SJ
Thu Sep 05 00:00:00 EDT 2019
Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells.
Neuroscience
Jeong B,Kim TH,Kim DS,Shin WH,Lee JR,Kim NS,Lee DY
Mon Jul 15 00:00:00 EDT 2019
Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex.
Current biology : CB
Gerondopoulos A,Strutt H,Stevenson NL,Sobajima T,Levine TP,Stephens DJ,Strutt D,Barr FA
Mon Oct 07 00:00:00 EDT 2019
Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.
Cell reports
Uzquiano A,Cifuentes-Diaz C,Jabali A,Romero DM,Houllier A,Dingli F,Maillard C,Boland A,Deleuze JF,Loew D,Mancini GMS,Bahi-Buisson N,Ladewig J,Francis F
Tue Aug 06 00:00:00 EDT 2019
Mutagenesis of putative ciliary genes with the CRISPR/Cas9 system in zebrafish identifies genes required for retinal development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hu R,Huang W,Liu J,Jin M,Wu Y,Li J,Wang J,Yu Z,Wang H,Cao Y
Mon Apr 01 00:00:00 EDT 2019
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Scientific reports
Conkar D,Bayraktar H,Firat-Karalar EN
Thu Oct 03 00:00:00 EDT 2019
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Scientific reports
Conkar D,Bayraktar H,Firat-Karalar EN
Thu Oct 03 00:00:00 EDT 2019
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Scientific reports
Martin-Hurtado A,Martin-Morales R,Robledinos-Antón N,Blanco R,Palacios-Blanco I,Lastres-Becker I,Cuadrado A,Garcia-Gonzalo FR
Wed Sep 25 00:00:00 EDT 2019
Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1.
Protein & cell
Mao H,Tang Z,Li H,Sun B,Tan M,Fan S,Zhu Y,Sun Y
Tue Oct 01 00:00:00 EDT 2019
Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration.
Journal of cell science
Muñoz-Estrada J,Ferland RJ
Wed Sep 04 00:00:00 EDT 2019
Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration.
Journal of cell science
Muñoz-Estrada J,Ferland RJ
Wed Sep 04 00:00:00 EDT 2019
Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia.
Biology open
Nozaki S,Castro Araya RF,Katoh Y,Nakayama K
Tue Sep 17 00:00:00 EDT 2019
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
Nature
Johnson MB,Sun X,Kodani A,Borges-Monroy R,Girskis KM,Ryu SC,Wang PP,Patel K,Gonzalez DM,Woo YM,Yan Z,Liang B,Smith RS,Chatterjee M,Coman D,Papademetris X,Staib LH,Hyder F,Mandeville JB,Grant PE,Im K,Kwak H,Engelhardt JF,Walsh CA,Bae BI
Sun Apr 01 00:00:00 EDT 2018
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
Nature
Johnson MB,Sun X,Kodani A,Borges-Monroy R,Girskis KM,Ryu SC,Wang PP,Patel K,Gonzalez DM,Woo YM,Yan Z,Liang B,Smith RS,Chatterjee M,Coman D,Papademetris X,Staib LH,Hyder F,Mandeville JB,Grant PE,Im K,Kwak H,Engelhardt JF,Walsh CA,Bae BI
Sun Apr 01 00:00:00 EDT 2018
A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy.
Nature
Sánchez-Danés A,Larsimont JC,Liagre M,Muñoz-Couselo E,Lapouge G,Brisebarre A,Dubois C,Suppa M,Sukumaran V,Del Marmol V,Tabernero J,Blanpain C
Mon Oct 01 00:00:00 EDT 2018
A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy.
Nature
Sánchez-Danés A,Larsimont JC,Liagre M,Muñoz-Couselo E,Lapouge G,Brisebarre A,Dubois C,Suppa M,Sukumaran V,Del Marmol V,Tabernero J,Blanpain C
Mon Oct 01 00:00:00 EDT 2018
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Cancer cell
Zingg D,Debbache J,Peña-Hernández R,Antunes AT,Schaefer SM,Cheng PF,Zimmerli D,Haeusel J,Calçada RR,Tuncer E,Zhang Y,Bossart R,Wong KK,Basler K,Dummer R,Santoro R,Levesque MP,Sommer L
Mon Jul 09 00:00:00 EDT 2018
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Cancer cell
Zingg D,Debbache J,Peña-Hernández R,Antunes AT,Schaefer SM,Cheng PF,Zimmerli D,Haeusel J,Calçada RR,Tuncer E,Zhang Y,Bossart R,Wong KK,Basler K,Dummer R,Santoro R,Levesque MP,Sommer L
Mon Jul 09 00:00:00 EDT 2018
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Cancer cell
Zingg D,Debbache J,Peña-Hernández R,Antunes AT,Schaefer SM,Cheng PF,Zimmerli D,Haeusel J,Calçada RR,Tuncer E,Zhang Y,Bossart R,Wong KK,Basler K,Dummer R,Santoro R,Levesque MP,Sommer L
Mon Jul 09 00:00:00 EDT 2018
Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.
Kidney international
Wang Q,Cobo-Stark P,Patel V,Somlo S,Han PL,Igarashi P
Thu Feb 01 00:00:00 EST 2018
Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.
Kidney international
Wang Q,Cobo-Stark P,Patel V,Somlo S,Han PL,Igarashi P
Thu Feb 01 00:00:00 EST 2018
Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7.
Neuron
Tavano S,Taverna E,Kalebic N,Haffner C,Namba T,Dahl A,Wilsch-Bräuninger M,Paridaen JTML,Huttner WB
Wed Mar 21 00:00:00 EDT 2018
Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7.
Neuron
Tavano S,Taverna E,Kalebic N,Haffner C,Namba T,Dahl A,Wilsch-Bräuninger M,Paridaen JTML,Huttner WB
Wed Mar 21 00:00:00 EDT 2018
Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination.
Neuron
Park SM,Lim JS,Ramakrishina S,Kim SH,Kim WK,Lee J,Kang HC,Reiter JF,Kim DS,Kim HH,Lee JH
Wed Jul 11 00:00:00 EDT 2018
Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination.
Neuron
Park SM,Lim JS,Ramakrishina S,Kim SH,Kim WK,Lee J,Kang HC,Reiter JF,Kim DS,Kim HH,Lee JH
Wed Jul 11 00:00:00 EDT 2018
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
The EMBO journal
Wiegering A,Dildrop R,Kalfhues L,Spychala A,Kuschel S,Lier JM,Zobel T,Dahmen S,Leu T,Struchtrup A,Legendre F,Vesque C,Schneider-Maunoury S,Saunier S,Rüther U,Gerhardt C
Tue May 15 00:00:00 EDT 2018
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
The EMBO journal
Wiegering A,Dildrop R,Kalfhues L,Spychala A,Kuschel S,Lier JM,Zobel T,Dahmen S,Leu T,Struchtrup A,Legendre F,Vesque C,Schneider-Maunoury S,Saunier S,Rüther U,Gerhardt C
Tue May 15 00:00:00 EDT 2018
A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.
Developmental cell
Ford MJ,Yeyati PL,Mali GR,Keighren MA,Waddell SH,Mjoseng HK,Douglas AT,Hall EA,Sakaue-Sawano A,Miyawaki A,Meehan RR,Boulter L,Jackson IJ,Mill P,Mort RL
Mon Nov 19 00:00:00 EST 2018
A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.
Developmental cell
Ford MJ,Yeyati PL,Mali GR,Keighren MA,Waddell SH,Mjoseng HK,Douglas AT,Hall EA,Sakaue-Sawano A,Miyawaki A,Meehan RR,Boulter L,Jackson IJ,Mill P,Mort RL
Mon Nov 19 00:00:00 EST 2018
The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK.
Developmental cell
Stephen LA,ElMaghloob Y,McIlwraith MJ,Yelland T,Castro Sanchez P,Roda-Navarro P,Ismail S
Mon Oct 08 00:00:00 EDT 2018
The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK.
Developmental cell
Stephen LA,ElMaghloob Y,McIlwraith MJ,Yelland T,Castro Sanchez P,Roda-Navarro P,Ismail S
Mon Oct 08 00:00:00 EDT 2018
Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo.
Autophagy
Liu ZQ,Lee JN,Son M,Lim JY,Dutta RK,Maharjan Y,Kwak S,Oh GT,Byun K,Choe SK,Park R
Wed Oct 02 00:00:00 EDT 2019
Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo.
Autophagy
Liu ZQ,Lee JN,Son M,Lim JY,Dutta RK,Maharjan Y,Kwak S,Oh GT,Byun K,Choe SK,Park R
Wed Oct 02 00:00:00 EDT 2019
Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model.
Proceedings of the National Academy of Sciences of the United States of America
Ramsbottom SA,Molinari E,Srivastava S,Silberman F,Henry C,Alkanderi S,Devlin LA,White K,Steel DH,Saunier S,Miles CG,Sayer JA
Tue Dec 04 00:00:00 EST 2018
Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model.
Proceedings of the National Academy of Sciences of the United States of America
Ramsbottom SA,Molinari E,Srivastava S,Silberman F,Henry C,Alkanderi S,Devlin LA,White K,Steel DH,Saunier S,Miles CG,Sayer JA
Tue Dec 04 00:00:00 EST 2018
Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model.
Proceedings of the National Academy of Sciences of the United States of America
Ramsbottom SA,Molinari E,Srivastava S,Silberman F,Henry C,Alkanderi S,Devlin LA,White K,Steel DH,Saunier S,Miles CG,Sayer JA
Tue Dec 04 00:00:00 EST 2018
Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
Experimental & molecular medicine
Dafinger C,Rinschen MM,Borgal L,Ehrenberg C,Basten SG,Franke M,Höhne M,Rauh M,Göbel H,Bloch W,Wunderlich FT,Peters DJM,Tasche D,Mishra T,Habbig S,Dötsch J,Müller RU,Brüning JC,Persigehl T,Giles RH,Benzing T,Schermer B,Liebau MC
Thu Jun 28 00:00:00 EDT 2018
Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
Experimental & molecular medicine
Dafinger C,Rinschen MM,Borgal L,Ehrenberg C,Basten SG,Franke M,Höhne M,Rauh M,Göbel H,Bloch W,Wunderlich FT,Peters DJM,Tasche D,Mishra T,Habbig S,Dötsch J,Müller RU,Brüning JC,Persigehl T,Giles RH,Benzing T,Schermer B,Liebau MC
Thu Jun 28 00:00:00 EDT 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition.
American journal of human genetics
Alkanderi S,Molinari E,Shaheen R,Elmaghloob Y,Stephen LA,Sammut V,Ramsbottom SA,Srivastava S,Cairns G,Edwards N,Rice SJ,Ewida N,Alhashem A,White K,Miles CG,Steel DH,Alkuraya FS,Ismail S,Sayer JA
Thu Oct 04 00:00:00 EDT 2018
ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition.
American journal of human genetics
Alkanderi S,Molinari E,Shaheen R,Elmaghloob Y,Stephen LA,Sammut V,Ramsbottom SA,Srivastava S,Cairns G,Edwards N,Rice SJ,Ewida N,Alhashem A,White K,Miles CG,Steel DH,Alkuraya FS,Ismail S,Sayer JA
Thu Oct 04 00:00:00 EDT 2018
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 EDT 2018
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 EDT 2018
WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.
EMBO reports
Kim YJ,Osborn DP,Lee JY,Araki M,Araki K,Mohun T,Känsäkoski J,Brandstack N,Kim HT,Miralles F,Kim CH,Brown NA,Kim HG,Martinez-Barbera JP,Ataliotis P,Raivio T,Layman LC,Kim SH
Thu Feb 01 00:00:00 EST 2018
WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.
EMBO reports
Kim YJ,Osborn DP,Lee JY,Araki M,Araki K,Mohun T,Känsäkoski J,Brandstack N,Kim HT,Miralles F,Kim CH,Brown NA,Kim HG,Martinez-Barbera JP,Ataliotis P,Raivio T,Layman LC,Kim SH
Thu Feb 01 00:00:00 EST 2018
Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.
Oncogene
Lee J,Yi S,Won M,Song YS,Yi HS,Park YJ,Park KC,Kim JT,Chang JY,Lee MJ,Sul HJ,Choi JE,Kim KS,Kero J,Kim J,Shong M
Wed Aug 01 00:00:00 EDT 2018
Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.
Oncogene
Lee J,Yi S,Won M,Song YS,Yi HS,Park YJ,Park KC,Kim JT,Chang JY,Lee MJ,Sul HJ,Choi JE,Kim KS,Kero J,Kim J,Shong M
Wed Aug 01 00:00:00 EDT 2018
Centrobin controls primary ciliogenesis in vertebrates.
The Journal of cell biology
Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG
Mon Apr 02 00:00:00 EDT 2018
Centrobin controls primary ciliogenesis in vertebrates.
The Journal of cell biology
Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG
Mon Apr 02 00:00:00 EDT 2018
Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
The Journal of cell biology
Vion AC,Alt S,Klaus-Bergmann A,Szymborska A,Zheng T,Perovic T,Hammoutene A,Oliveira MB,Bartels-Klein E,Hollfinger I,Rautou PE,Bernabeu MO,Gerhardt H
Mon May 07 00:00:00 EDT 2018
Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
The Journal of cell biology
Vion AC,Alt S,Klaus-Bergmann A,Szymborska A,Zheng T,Perovic T,Hammoutene A,Oliveira MB,Bartels-Klein E,Hollfinger I,Rautou PE,Bernabeu MO,Gerhardt H
Mon May 07 00:00:00 EDT 2018
The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression.
The Journal of cell biology
Fernández-Barrera J,Bernabé-Rubio M,Casares-Arias J,Rangel L,Fernández-Martín L,Correas I,Alonso MA
Mon Mar 05 00:00:00 EST 2018
Homozygous variants in KIAA1549, encoding a ciliary protein, are associated with autosomal recessive retinitis pigmentosa.
Journal of medical genetics
de Bruijn SE,Verbakel SK,de Vrieze E,Kremer H,Cremers FPM,Hoyng CB,van den Born LI,Roosing S
Mon Oct 01 00:00:00 EDT 2018
Homozygous variants in KIAA1549, encoding a ciliary protein, are associated with autosomal recessive retinitis pigmentosa.
Journal of medical genetics
de Bruijn SE,Verbakel SK,de Vrieze E,Kremer H,Cremers FPM,Hoyng CB,van den Born LI,Roosing S
Mon Oct 01 00:00:00 EDT 2018
Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SH,Joo K,Jung EJ,Hong H,Seo J,Kim J
Thu Feb 01 00:00:00 EST 2018
Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SH,Joo K,Jung EJ,Hong H,Seo J,Kim J
Thu Feb 01 00:00:00 EST 2018
Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP-1-mediated endocytosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Coveney CR,Collins I,Mc Fie M,Chanalaris A,Yamamoto K,Wann AKT
Tue Jun 19 00:00:00 EDT 2018
Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP-1-mediated endocytosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Coveney CR,Collins I,Mc Fie M,Chanalaris A,Yamamoto K,Wann AKT
Tue Jun 19 00:00:00 EDT 2018
Primary cilia-regulated transcriptome in the renal collecting duct.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mohammed SG,Arjona FJ,Verschuren EHJ,Bakey Z,Alkema W,van Hijum S,Schmidts M,Bindels RJM,Hoenderop JGJ
Sun Jul 01 00:00:00 EDT 2018
Primary cilia-regulated transcriptome in the renal collecting duct.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mohammed SG,Arjona FJ,Verschuren EHJ,Bakey Z,Alkema W,van Hijum S,Schmidts M,Bindels RJM,Hoenderop JGJ
Sun Jul 01 00:00:00 EDT 2018
Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors.
The American journal of pathology
Shannon ML,Fame RM,Chau KF,Dani N,Calicchio ML,Géléoc GS,Lidov HGW,Alexandrescu S,Lehtinen MK
Fri Jun 01 00:00:00 EDT 2018
Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors.
The American journal of pathology
Shannon ML,Fame RM,Chau KF,Dani N,Calicchio ML,Géléoc GS,Lidov HGW,Alexandrescu S,Lehtinen MK
Fri Jun 01 00:00:00 EDT 2018
Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors.
The American journal of pathology
Shannon ML,Fame RM,Chau KF,Dani N,Calicchio ML,Géléoc GS,Lidov HGW,Alexandrescu S,Lehtinen MK
Fri Jun 01 00:00:00 EDT 2018
Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control.
Journal of cell science
Stevenson NL,Bergen DJM,Xu A,Wyatt E,Henry F,McCaughey J,Vuolo L,Hammond CL,Stephens DJ
Fri May 04 00:00:00 EDT 2018
Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control.
Journal of cell science
Stevenson NL,Bergen DJM,Xu A,Wyatt E,Henry F,McCaughey J,Vuolo L,Hammond CL,Stephens DJ
Fri May 04 00:00:00 EDT 2018
The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane.
Journal of cell science
Revenkova E,Liu Q,Gusella GL,Iomini C
Fri May 04 00:00:00 EDT 2018
The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane.
Journal of cell science
Revenkova E,Liu Q,Gusella GL,Iomini C
Fri May 04 00:00:00 EDT 2018
Glucose deprivation induces primary cilium formation through mTORC1 inactivation.
Journal of cell science
Takahashi K,Nagai T,Chiba S,Nakayama K,Mizuno K
Mon Jan 08 00:00:00 EST 2018
Glucose deprivation induces primary cilium formation through mTORC1 inactivation.
Journal of cell science
Takahashi K,Nagai T,Chiba S,Nakayama K,Mizuno K
Mon Jan 08 00:00:00 EST 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 EST 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 EST 2018
LRRC45 contributes to early steps of axoneme extension.
Journal of cell science
Kurtulmus B,Yuan C,Schuy J,Neuner A,Hata S,Kalamakis G,Martin-Villalba A,Pereira G
Thu Sep 20 00:00:00 EDT 2018
LRRC45 contributes to early steps of axoneme extension.
Journal of cell science
Kurtulmus B,Yuan C,Schuy J,Neuner A,Hata S,Kalamakis G,Martin-Villalba A,Pereira G
Thu Sep 20 00:00:00 EDT 2018
LRRC45 contributes to early steps of axoneme extension.
Journal of cell science
Kurtulmus B,Yuan C,Schuy J,Neuner A,Hata S,Kalamakis G,Martin-Villalba A,Pereira G
Thu Sep 20 00:00:00 EDT 2018
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Human molecular genetics
Martin L,Kaci N,Estibals V,Goudin N,Garfa-Traore M,Benoist-Lasselin C,Dambroise E,Legeai-Mallet L
Mon Jan 01 00:00:00 EST 2018
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Human molecular genetics
Martin L,Kaci N,Estibals V,Goudin N,Garfa-Traore M,Benoist-Lasselin C,Dambroise E,Legeai-Mallet L
Mon Jan 01 00:00:00 EST 2018
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Human molecular genetics
Martin L,Kaci N,Estibals V,Goudin N,Garfa-Traore M,Benoist-Lasselin C,Dambroise E,Legeai-Mallet L
Mon Jan 01 00:00:00 EST 2018
Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies.
Human molecular genetics
Ryan R,Failler M,Reilly ML,Garfa-Traore M,Delous M,Filhol E,Reboul T,Bole-Feysot C,Nitschké P,Baudouin V,Amselem S,Escudier E,Legendre M,Benmerah A,Saunier S
Mon Jan 15 00:00:00 EST 2018
Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies.
Human molecular genetics
Ryan R,Failler M,Reilly ML,Garfa-Traore M,Delous M,Filhol E,Reboul T,Bole-Feysot C,Nitschké P,Baudouin V,Amselem S,Escudier E,Legendre M,Benmerah A,Saunier S
Mon Jan 15 00:00:00 EST 2018
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Human molecular genetics
Hartill VL,van de Hoek G,Patel MP,Little R,Watson CM,Berry IR,Shoemark A,Abdelmottaleb D,Parkes E,Bacchelli C,Szymanska K,Knoers NV,Scambler PJ,Ueffing M,Boldt K,Yates R,Winyard PJ,Adler B,Moya E,Hattingh L,Shenoy A,Hogg C,Sheridan E,Roepman R,Norris D,Mitchison HM,Giles RH,Johnson CA
Thu Feb 01 00:00:00 EST 2018
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Human molecular genetics
Hartill VL,van de Hoek G,Patel MP,Little R,Watson CM,Berry IR,Shoemark A,Abdelmottaleb D,Parkes E,Bacchelli C,Szymanska K,Knoers NV,Scambler PJ,Ueffing M,Boldt K,Yates R,Winyard PJ,Adler B,Moya E,Hattingh L,Shenoy A,Hogg C,Sheridan E,Roepman R,Norris D,Mitchison HM,Giles RH,Johnson CA
Thu Feb 01 00:00:00 EST 2018
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Human molecular genetics
Barny I,Perrault I,Michel C,Soussan M,Goudin N,Rio M,Thomas S,Attié-Bitach T,Hamel C,Dollfus H,Kaplan J,Rozet JM,Gerard X
Wed Aug 01 00:00:00 EDT 2018
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Human molecular genetics
Barny I,Perrault I,Michel C,Soussan M,Goudin N,Rio M,Thomas S,Attié-Bitach T,Hamel C,Dollfus H,Kaplan J,Rozet JM,Gerard X
Wed Aug 01 00:00:00 EDT 2018
Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies.
Human molecular genetics
Kunova Bosakova M,Varecha M,Hampl M,Duran I,Nita A,Buchtova M,Dosedelova H,Machat R,Xie Y,Ni Z,Martin JH,Chen L,Jansen G,Krakow D,Krejci P
Thu Mar 15 00:00:00 EDT 2018
Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies.
Human molecular genetics
Kunova Bosakova M,Varecha M,Hampl M,Duran I,Nita A,Buchtova M,Dosedelova H,Machat R,Xie Y,Ni Z,Martin JH,Chen L,Jansen G,Krakow D,Krejci P
Thu Mar 15 00:00:00 EDT 2018
Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.
Human molecular genetics
Broix L,Asselin L,Silva CG,Ivanova EL,Tilly P,Gilet JG,Lebrun N,Jagline H,Muraca G,Saillour Y,Drouot N,Reilly ML,Francis F,Benmerah A,Bahi-Buisson N,Belvindrah R,Nguyen L,Godin JD,Chelly J,Hinckelmann MV
Mon Jan 15 00:00:00 EST 2018
Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.
Human molecular genetics
Broix L,Asselin L,Silva CG,Ivanova EL,Tilly P,Gilet JG,Lebrun N,Jagline H,Muraca G,Saillour Y,Drouot N,Reilly ML,Francis F,Benmerah A,Bahi-Buisson N,Belvindrah R,Nguyen L,Godin JD,Chelly J,Hinckelmann MV
Mon Jan 15 00:00:00 EST 2018
Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Abdelhamed ZA,Ryan TA,Fuller M,Coulson-Gilmer C,Abdelmottaleb DI,Wang TL,Kaun JC,Wang P,Hutson R,Wilkinson N,Bell SM,Johnson CA
Mon Oct 01 00:00:00 EDT 2018
Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Abdelhamed ZA,Ryan TA,Fuller M,Coulson-Gilmer C,Abdelmottaleb DI,Wang TL,Kaun JC,Wang P,Hutson R,Wilkinson N,Bell SM,Johnson CA
Mon Oct 01 00:00:00 EDT 2018
Autophagy alteration prevents primary cilium disassembly in RPE1 cells.
Biochemical and biophysical research communications
Maharjan Y,Lee JN,Kwak S,Lim H,Dutta RK,Liu ZQ,So HS,Park R
Sat Jun 02 00:00:00 EDT 2018
Autophagy alteration prevents primary cilium disassembly in RPE1 cells.
Biochemical and biophysical research communications
Maharjan Y,Lee JN,Kwak S,Lim H,Dutta RK,Liu ZQ,So HS,Park R
Sat Jun 02 00:00:00 EDT 2018
Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition.
Biochemical and biophysical research communications
Han SJ,Jung JK,Im SS,Lee SR,Jang BC,Park KM,Kim JI
Mon Feb 05 00:00:00 EST 2018
Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition.
Biochemical and biophysical research communications
Han SJ,Jung JK,Im SS,Lee SR,Jang BC,Park KM,Kim JI
Mon Feb 05 00:00:00 EST 2018
Dorsoventral differences in cAMP levels and correlated changes in the subcellular distribution of the PKA catalytic domain, provide further evidence that PKA signaling coordinates dorsoventral patterning of the otocyst.
Development, growth & differentiation
Ohta S,Schoenwolf GC
Sat Sep 01 00:00:00 EDT 2018
Dorsoventral differences in cAMP levels and correlated changes in the subcellular distribution of the PKA catalytic domain, provide further evidence that PKA signaling coordinates dorsoventral patterning of the otocyst.
Development, growth & differentiation
Ohta S,Schoenwolf GC
Sat Sep 01 00:00:00 EDT 2018
Quantitative Comparison of Primary Cilia Marker Expression and Length in the Mouse Brain.
Journal of molecular neuroscience : MN
Sipos É,Komoly S,Ács P
Thu Mar 01 00:00:00 EST 2018
Quantitative Comparison of Primary Cilia Marker Expression and Length in the Mouse Brain.
Journal of molecular neuroscience : MN
Sipos É,Komoly S,Ács P
Thu Mar 01 00:00:00 EST 2018
Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.
Biology open
Takei R,Katoh Y,Nakayama K
Mon Apr 30 00:00:00 EDT 2018
Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.
Biology open
Takei R,Katoh Y,Nakayama K
Mon Apr 30 00:00:00 EDT 2018
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 EST 2018
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 EST 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Tue Jun 05 00:00:00 EDT 2018
Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy.
Human molecular genetics
Cabaud O,Roubin R,Comte A,Bascunana V,Sergé A,Sedjaï F,Birnbaum D,Rosnet O,Acquaviva C
Mon Oct 01 00:00:00 EDT 2018
Reconstructing the Human Renal Vascular-Tubular Unit In Vitro.
Advanced healthcare materials
Rayner SG,Phong KT,Xue J,Lih D,Shankland SJ,Kelly EJ,Himmelfarb J,Zheng Y
Sat Dec 01 00:00:00 EST 2018
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa.
Nature communications
Buskin A,Zhu L,Chichagova V,Basu B,Mozaffari-Jovin S,Dolan D,Droop A,Collin J,Bronstein R,Mehrotra S,Farkas M,Hilgen G,White K,Pan KT,Treumann A,Hallam D,Bialas K,Chung G,Mellough C,Ding Y,Krasnogor N,Przyborski S,Zwolinski S,Al-Aama J,Alharthi S,Xu Y,Wheway G,Szymanska K,McKibbin M,Inglehearn CF,Elliott DJ,Lindsay S,Ali RR,Steel DH,Armstrong L,Sernagor E,Urlaub H,Pierce E,Lührmann R,Grellscheid SN,Johnson CA,Lako M
Fri Oct 12 00:00:00 EDT 2018
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa.
Nature communications
Buskin A,Zhu L,Chichagova V,Basu B,Mozaffari-Jovin S,Dolan D,Droop A,Collin J,Bronstein R,Mehrotra S,Farkas M,Hilgen G,White K,Pan KT,Treumann A,Hallam D,Bialas K,Chung G,Mellough C,Ding Y,Krasnogor N,Przyborski S,Zwolinski S,Al-Aama J,Alharthi S,Xu Y,Wheway G,Szymanska K,McKibbin M,Inglehearn CF,Elliott DJ,Lindsay S,Ali RR,Steel DH,Armstrong L,Sernagor E,Urlaub H,Pierce E,Lührmann R,Grellscheid SN,Johnson CA,Lako M
Fri Oct 12 00:00:00 EDT 2018
CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.
Molecular & cellular proteomics : MCP
Beyer T,Bolz S,Junger K,Horn N,Moniruzzaman M,Wissinger Y,Ueffing M,Boldt K
Sun Jul 01 00:00:00 EDT 2018
CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.
Molecular & cellular proteomics : MCP
Beyer T,Bolz S,Junger K,Horn N,Moniruzzaman M,Wissinger Y,Ueffing M,Boldt K
Sun Jul 01 00:00:00 EDT 2018
Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells.
Cell reports
May-Simera HL,Wan Q,Jha BS,Hartford J,Khristov V,Dejene R,Chang J,Patnaik S,Lu Q,Banerjee P,Silver J,Insinna-Kettenhofen C,Patel D,Lotfi M,Malicdan M,Hotaling N,Maminishkis A,Sridharan R,Brooks B,Miyagishima K,Gunay-Aygun M,Pal R,Westlake C,Miller S,Sharma R,Bharti K
Tue Jan 02 00:00:00 EST 2018
Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells.
Cell reports
May-Simera HL,Wan Q,Jha BS,Hartford J,Khristov V,Dejene R,Chang J,Patnaik S,Lu Q,Banerjee P,Silver J,Insinna-Kettenhofen C,Patel D,Lotfi M,Malicdan M,Hotaling N,Maminishkis A,Sridharan R,Brooks B,Miyagishima K,Gunay-Aygun M,Pal R,Westlake C,Miller S,Sharma R,Bharti K
Tue Jan 02 00:00:00 EST 2018
Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling.
Nature communications
Vuong LT,Iomini C,Balmer S,Esposito D,Aaronson SA,Mlodzik M
Thu Dec 13 00:00:00 EST 2018
Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling.
Nature communications
Vuong LT,Iomini C,Balmer S,Esposito D,Aaronson SA,Mlodzik M
Thu Dec 13 00:00:00 EST 2018
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.
Nature communications
Huang N,Zhang D,Li F,Chai P,Wang S,Teng J,Chen J
Tue Oct 30 00:00:00 EDT 2018
Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.
Cell death & disease
Wang B,Zhang Y,Dong H,Gong S,Wei B,Luo M,Wang H,Wu X,Liu W,Xu X,Zheng Y,Sun M
Tue May 01 00:00:00 EDT 2018
Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.
Cell death & disease
Wang B,Zhang Y,Dong H,Gong S,Wei B,Luo M,Wang H,Wu X,Liu W,Xu X,Zheng Y,Sun M
Tue May 01 00:00:00 EDT 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 EDT 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 EDT 2018
Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.
Brain structure & function
Ehrlich AT,Semache M,Bailly J,Wojcik S,Arefin TM,Colley C,Le Gouill C,Gross F,Lukasheva V,Hogue M,Darcq E,Harsan LA,Bouvier M,Kieffer BL
Sun Apr 01 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
A distal centriolar protein network controls organelle maturation and asymmetry.
Nature communications
Wang L,Failler M,Fu W,Dynlacht BD
Wed Sep 26 00:00:00 EDT 2018
Adenylyl cyclases and TRPV4 mediate Ca2+/cAMP dynamics to enhance fluid flow-induced osteogenesis in osteocytes.
Journal of molecular biochemistry
Moore ER,Ryu HS,Zhu YX,Jacobs CR
Thu Oct 01 00:00:00 EDT 2020
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications
He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J
Fri Aug 17 00:00:00 EDT 2018
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications
He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J
Fri Aug 17 00:00:00 EDT 2018
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications
He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J
Fri Aug 17 00:00:00 EDT 2018
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications
He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J
Fri Aug 17 00:00:00 EDT 2018
Membrane association and remodeling by intraflagellar transport protein IFT172.
Nature communications
Wang Q,Taschner M,Ganzinger KA,Kelley C,Villasenor A,Heymann M,Schwille P,Lorentzen E,Mizuno N
Thu Nov 08 00:00:00 EST 2018
Membrane association and remodeling by intraflagellar transport protein IFT172.
Nature communications
Wang Q,Taschner M,Ganzinger KA,Kelley C,Villasenor A,Heymann M,Schwille P,Lorentzen E,Mizuno N
Thu Nov 08 00:00:00 EST 2018
Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles.
Cilia
Hoang-Minh LB,Dutra-Clarke M,Breunig JJ,Sarkisian MR
Fri Apr 08 00:00:00 EDT 2022
Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles.
Cilia
Hoang-Minh LB,Dutra-Clarke M,Breunig JJ,Sarkisian MR
Fri Apr 08 00:00:00 EDT 2022
CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.
Cell reports
Canning P,Park K,Gonçalves J,Li C,Howard CJ,Sharpe TD,Holt LJ,Pelletier L,Bullock AN,Leroux MR
Tue Jan 23 00:00:00 EST 2018
CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.
Cell reports
Canning P,Park K,Gonçalves J,Li C,Howard CJ,Sharpe TD,Holt LJ,Pelletier L,Bullock AN,Leroux MR
Tue Jan 23 00:00:00 EST 2018
Guided self-organization and cortical plate formation in human brain organoids.
Nature biotechnology
Lancaster MA,Corsini NS,Wolfinger S,Gustafson EH,Phillips AW,Burkard TR,Otani T,Livesey FJ,Knoblich JA
Sat Jul 01 00:00:00 EDT 2017
Guided self-organization and cortical plate formation in human brain organoids.
Nature biotechnology
Lancaster MA,Corsini NS,Wolfinger S,Gustafson EH,Phillips AW,Burkard TR,Otani T,Livesey FJ,Knoblich JA
Sat Jul 01 00:00:00 EDT 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Cell
Phua SC,Chiba S,Suzuki M,Su E,Roberson EC,Pusapati GV,Schurmans S,Setou M,Rohatgi R,Reiter JF,Ikegami K,Inoue T
Thu Jan 12 00:00:00 EST 2017
Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.
Cell
Kopinke D,Roberson EC,Reiter JF
Thu Jul 13 00:00:00 EDT 2017
Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.
Cell
Kopinke D,Roberson EC,Reiter JF
Thu Jul 13 00:00:00 EDT 2017
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.
Nature genetics
Lu H,Galeano MCR,Ott E,Kaeslin G,Kausalya PJ,Kramer C,Ortiz-Brüchle N,Hilger N,Metzis V,Hiersche M,Tay SY,Tunningley R,Vij S,Courtney AD,Whittle B,Wühl E,Vester U,Hartleben B,Neuber S,Frank V,Little MH,Epting D,Papathanasiou P,Perkins AC,Wright GD,Hunziker W,Gee HY,Otto EA,Zerres K,Hildebrandt F,Roy S,Wicking C,Bergmann C
Sat Jul 01 00:00:00 EDT 2017
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.
Nature genetics
Lu H,Galeano MCR,Ott E,Kaeslin G,Kausalya PJ,Kramer C,Ortiz-Brüchle N,Hilger N,Metzis V,Hiersche M,Tay SY,Tunningley R,Vij S,Courtney AD,Whittle B,Wühl E,Vester U,Hartleben B,Neuber S,Frank V,Little MH,Epting D,Papathanasiou P,Perkins AC,Wright GD,Hunziker W,Gee HY,Otto EA,Zerres K,Hildebrandt F,Roy S,Wicking C,Bergmann C
Sat Jul 01 00:00:00 EDT 2017
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
Developmental cell
Kanie T,Abbott KL,Mooney NA,Plowey ED,Demeter J,Jackson PK
Mon Jul 10 00:00:00 EDT 2017
Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.
Developmental cell
Sigg MA,Menchen T,Lee C,Johnson J,Jungnickel MK,Choksi SP,Garcia G,Busengdal H,Dougherty GW,Pennekamp P,Werner C,Rentzsch F,Florman HM,Krogan N,Wallingford JB,Omran H,Reiter JF
Mon Dec 18 00:00:00 EST 2017
Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.
Developmental cell
Sigg MA,Menchen T,Lee C,Johnson J,Jungnickel MK,Choksi SP,Garcia G,Busengdal H,Dougherty GW,Pennekamp P,Werner C,Rentzsch F,Florman HM,Krogan N,Wallingford JB,Omran H,Reiter JF
Mon Dec 18 00:00:00 EST 2017
CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
American journal of human genetics
Windpassinger C,Piard J,Bonnard C,Alfadhel M,Lim S,Bisteau X,Blouin S,Ali NB,Ng AYJ,Lu H,Tohari S,Talib SZA,van Hul N,Caldez MJ,Van Maldergem L,Yigit G,Kayserili H,Youssef SA,Coppola V,de Bruin A,Tessarollo L,Choi H,Rupp V,Roetzer K,Roschger P,Klaushofer K,Altmüller J,Roy S,Venkatesh B,Ganger R,Grill F,Ben Chehida F,Wollnik B,Altunoglu U,Al Kaissi A,Reversade B,Kaldis P
Thu Sep 07 00:00:00 EDT 2017
CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
American journal of human genetics
Windpassinger C,Piard J,Bonnard C,Alfadhel M,Lim S,Bisteau X,Blouin S,Ali NB,Ng AYJ,Lu H,Tohari S,Talib SZA,van Hul N,Caldez MJ,Van Maldergem L,Yigit G,Kayserili H,Youssef SA,Coppola V,de Bruin A,Tessarollo L,Choi H,Rupp V,Roetzer K,Roschger P,Klaushofer K,Altmüller J,Roy S,Venkatesh B,Ganger R,Grill F,Ben Chehida F,Wollnik B,Altunoglu U,Al Kaissi A,Reversade B,Kaldis P
Thu Sep 07 00:00:00 EDT 2017
The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.
EMBO reports
Kohli P,Höhne M,Jüngst C,Bertsch S,Ebert LK,Schauss AC,Benzing T,Rinschen MM,Schermer B
Fri Sep 01 00:00:00 EDT 2017
The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.
EMBO reports
Kohli P,Höhne M,Jüngst C,Bertsch S,Ebert LK,Schauss AC,Benzing T,Rinschen MM,Schermer B
Fri Sep 01 00:00:00 EDT 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma.
EMBO reports
Kobayashi T,Nakazono K,Tokuda M,Mashima Y,Dynlacht BD,Itoh H
Wed Feb 01 00:00:00 EST 2017
An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells.
The Journal of cell biology
Taniguchi K,Shao Y,Townshend RF,Cortez CL,Harris CE,Meshinchi S,Kalantry S,Fu J,O'Shea KS,Gumucio DL
Mon Dec 04 00:00:00 EST 2017
An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells.
The Journal of cell biology
Taniguchi K,Shao Y,Townshend RF,Cortez CL,Harris CE,Meshinchi S,Kalantry S,Fu J,O'Shea KS,Gumucio DL
Mon Dec 04 00:00:00 EST 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.
The Journal of cell biology
Yeyati PL,Schiller R,Mali G,Kasioulis I,Kawamura A,Adams IR,Playfoot C,Gilbert N,van Heyningen V,Wills J,von Kriegsheim A,Finch A,Sakai J,Schofield CJ,Jackson IJ,Mill P
Mon Apr 03 00:00:00 EDT 2017
GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.
Neurobiology of disease
Giddens MM,Wong JC,Schroeder JP,Farrow EG,Smith BM,Owino S,Soden SE,Meyer RC,Saunders C,LePichon JB,Weinshenker D,Escayg A,Hall RA
Sun Oct 01 00:00:00 EDT 2017
GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.
Neurobiology of disease
Giddens MM,Wong JC,Schroeder JP,Farrow EG,Smith BM,Owino S,Soden SE,Meyer RC,Saunders C,LePichon JB,Weinshenker D,Escayg A,Hall RA
Sun Oct 01 00:00:00 EDT 2017
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Journal of cellular physiology
Wang CY,Tsai HL,Syu JS,Chen TY,Su MT
Thu Jun 01 00:00:00 EDT 2017
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion.
Journal of cellular physiology
Wang CY,Tsai HL,Syu JS,Chen TY,Su MT
Thu Jun 01 00:00:00 EDT 2017
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.
Journal of cellular physiology
Thorpe SD,Gambassi S,Thompson CL,Chandrakumar C,Santucci A,Knight MM
Fri Sep 01 00:00:00 EDT 2017
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.
Journal of cellular physiology
Thorpe SD,Gambassi S,Thompson CL,Chandrakumar C,Santucci A,Knight MM
Fri Sep 01 00:00:00 EDT 2017
A novel role for primary cilia in airway remodeling.
American journal of physiology. Lung cellular and molecular physiology
Trempus CS,Song W,Lazrak A,Yu Z,Creighton JR,Young BM,Heise RL,Yu YR,Ingram JL,Tighe RM,Matalon S,Garantziotis S
Tue Aug 01 00:00:00 EDT 2017
A novel role for primary cilia in airway remodeling.
American journal of physiology. Lung cellular and molecular physiology
Trempus CS,Song W,Lazrak A,Yu Z,Creighton JR,Young BM,Heise RL,Yu YR,Ingram JL,Tighe RM,Matalon S,Garantziotis S
Tue Aug 01 00:00:00 EDT 2017
Missense mutations in the WD40 domain of AHI1 cause non-syndromic retinitis pigmentosa.
Journal of medical genetics
Nguyen TT,Hull S,Roepman R,van den Born LI,Oud MM,de Vrieze E,Hetterschijt L,Letteboer SJF,van Beersum SEC,Blokland EA,Yntema HG,Cremers FPM,van der Zwaag PA,Arno G,van Wijk E,Webster AR,Haer-Wigman L
Fri Sep 01 00:00:00 EDT 2017
Missense mutations in the WD40 domain of AHI1 cause non-syndromic retinitis pigmentosa.
Journal of medical genetics
Nguyen TT,Hull S,Roepman R,van den Born LI,Oud MM,de Vrieze E,Hetterschijt L,Letteboer SJF,van Beersum SEC,Blokland EA,Yntema HG,Cremers FPM,van der Zwaag PA,Arno G,van Wijk E,Webster AR,Haer-Wigman L
Fri Sep 01 00:00:00 EDT 2017
Mutations in KIAA0753 cause Joubert syndrome associated with growth hormone deficiency.
Human genetics
Stephen J,Vilboux T,Mian L,Kuptanon C,Sinclair CM,Yildirimli D,Maynard DM,Bryant J,Fischer R,Vemulapalli M,Mullikin JC,Huizing M,Gahl WA,Malicdan MCV,Gunay-Aygun M
Sat Apr 01 00:00:00 EDT 2017
Mutations in KIAA0753 cause Joubert syndrome associated with growth hormone deficiency.
Human genetics
Stephen J,Vilboux T,Mian L,Kuptanon C,Sinclair CM,Yildirimli D,Maynard DM,Bryant J,Fischer R,Vemulapalli M,Mullikin JC,Huizing M,Gahl WA,Malicdan MCV,Gunay-Aygun M
Sat Apr 01 00:00:00 EDT 2017
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Toriyama M,Toriyama M,Wallingford JB,Finnell RH
Tue Aug 01 00:00:00 EDT 2017
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Toriyama M,Toriyama M,Wallingford JB,Finnell RH
Tue Aug 01 00:00:00 EDT 2017
Estrogen receptor α is required for oviductal transport of embryos.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li S,O'Neill SR,Zhang Y,Holtzman MJ,Takemaru KI,Korach KS,Winuthayanon W
Sat Apr 01 00:00:00 EDT 2017
Estrogen receptor α is required for oviductal transport of embryos.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li S,O'Neill SR,Zhang Y,Holtzman MJ,Takemaru KI,Korach KS,Winuthayanon W
Sat Apr 01 00:00:00 EDT 2017
A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity.
European journal of human genetics : EJHG
Rafiullah R,Long AB,Ivanova AA,Ali H,Berkel S,Mustafa G,Paramasivam N,Schlesner M,Wiemann S,Wade RC,Bolthauser E,Blum M,Kahn RA,Caspary T,Rappold GA
Fri Dec 01 00:00:00 EST 2017
A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity.
European journal of human genetics : EJHG
Rafiullah R,Long AB,Ivanova AA,Ali H,Berkel S,Mustafa G,Paramasivam N,Schlesner M,Wiemann S,Wade RC,Bolthauser E,Blum M,Kahn RA,Caspary T,Rappold GA
Fri Dec 01 00:00:00 EST 2017
Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome.
Journal of cell science
Prosseda PP,Luo N,Wang B,Alvarado JA,Hu Y,Sun Y
Sun Oct 15 00:00:00 EDT 2017
Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome.
Journal of cell science
Prosseda PP,Luo N,Wang B,Alvarado JA,Hu Y,Sun Y
Sun Oct 15 00:00:00 EDT 2017
Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.
Journal of cell science
Nozaki S,Katoh Y,Terada M,Michisaka S,Funabashi T,Takahashi S,Kontani K,Nakayama K
Wed Feb 01 00:00:00 EST 2017
Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.
Journal of cell science
Nozaki S,Katoh Y,Terada M,Michisaka S,Funabashi T,Takahashi S,Kontani K,Nakayama K
Wed Feb 01 00:00:00 EST 2017
A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies.
Human molecular genetics
Srivastava S,Ramsbottom SA,Molinari E,Alkanderi S,Filby A,White K,Henry C,Saunier S,Miles CG,Sayer JA
Fri Dec 01 00:00:00 EST 2017
A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies.
Human molecular genetics
Srivastava S,Ramsbottom SA,Molinari E,Alkanderi S,Filby A,White K,Henry C,Saunier S,Miles CG,Sayer JA
Fri Dec 01 00:00:00 EST 2017
Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.
Genetics
Kazatskaya A,Kuhns S,Lambacher NJ,Kennedy JE,Brear AG,McManus GJ,Sengupta P,Blacque OE
Fri Dec 01 00:00:00 EST 2017
Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.
Genetics
Kazatskaya A,Kuhns S,Lambacher NJ,Kennedy JE,Brear AG,McManus GJ,Sengupta P,Blacque OE
Fri Dec 01 00:00:00 EST 2017
Human Embryonic Stem Cell-Derived Cardiomyocytes Self-Arrange with Areas of Different Subtypes During Differentiation.
Stem cells and development
Vestergaard ML,Grubb S,Koefoed K,Anderson-Jenkins Z,Grunnet-Lauridsen K,Calloe K,Clausen C,Christensen ST,Møllgård K,Andersen CY
Wed Nov 01 00:00:00 EDT 2017
Human Embryonic Stem Cell-Derived Cardiomyocytes Self-Arrange with Areas of Different Subtypes During Differentiation.
Stem cells and development
Vestergaard ML,Grubb S,Koefoed K,Anderson-Jenkins Z,Grunnet-Lauridsen K,Calloe K,Clausen C,Christensen ST,Møllgård K,Andersen CY
Wed Nov 01 00:00:00 EDT 2017
Human Embryonic Stem Cell-Derived Cardiomyocytes Self-Arrange with Areas of Different Subtypes During Differentiation.
Stem cells and development
Vestergaard ML,Grubb S,Koefoed K,Anderson-Jenkins Z,Grunnet-Lauridsen K,Calloe K,Clausen C,Christensen ST,Møllgård K,Andersen CY
Wed Nov 01 00:00:00 EDT 2017
Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.
Cellular and molecular neurobiology
Di Pietro C,Marazziti D,La Sala G,Abbaszadeh Z,Golini E,Matteoni R,Tocchini-Valentini GP
Sun Jan 01 00:00:00 EST 2017
Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.
Cellular and molecular neurobiology
Di Pietro C,Marazziti D,La Sala G,Abbaszadeh Z,Golini E,Matteoni R,Tocchini-Valentini GP
Sun Jan 01 00:00:00 EST 2017
Primary cilia on porcine testicular somatic cells and their role in hedgehog signaling and tubular morphogenesis in vitro.
Cell and tissue research
Dores C,Alpaugh W,Su L,Biernaskie J,Dobrinski I
Sat Apr 01 00:00:00 EDT 2017
Primary cilia on porcine testicular somatic cells and their role in hedgehog signaling and tubular morphogenesis in vitro.
Cell and tissue research
Dores C,Alpaugh W,Su L,Biernaskie J,Dobrinski I
Sat Apr 01 00:00:00 EDT 2017
Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification.
Molecular biology of the cell
Flanagan AM,Stavenschi E,Basavaraju S,Gaboriau D,Hoey DA,Morrison CG
Wed Mar 15 00:00:00 EDT 2017
Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification.
Molecular biology of the cell
Flanagan AM,Stavenschi E,Basavaraju S,Gaboriau D,Hoey DA,Morrison CG
Wed Mar 15 00:00:00 EDT 2017
Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.
Molecular biology of the cell
Katoh Y,Michisaka S,Nozaki S,Funabashi T,Hirano T,Takei R,Nakayama K
Sat Apr 01 00:00:00 EDT 2017
Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.
Molecular biology of the cell
Katoh Y,Michisaka S,Nozaki S,Funabashi T,Hirano T,Takei R,Nakayama K
Sat Apr 01 00:00:00 EDT 2017
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.
Molecular biology of the cell
Funabashi T,Katoh Y,Michisaka S,Terada M,Sugawa M,Nakayama K
Wed Mar 01 00:00:00 EST 2017
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.
Molecular biology of the cell
Funabashi T,Katoh Y,Michisaka S,Terada M,Sugawa M,Nakayama K
Wed Mar 01 00:00:00 EST 2017
Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division.
Developmental biology
Schock EN,Brugmann SA
Wed Nov 15 00:00:00 EST 2017
Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division.
Developmental biology
Schock EN,Brugmann SA
Wed Nov 15 00:00:00 EST 2017
Cilia-dependent GLI processing in neural crest cells is required for tongue development.
Developmental biology
Millington G,Elliott KH,Chang YT,Chang CF,Dlugosz A,Brugmann SA
Sat Apr 15 00:00:00 EDT 2017
Cilia-dependent GLI processing in neural crest cells is required for tongue development.
Developmental biology
Millington G,Elliott KH,Chang YT,Chang CF,Dlugosz A,Brugmann SA
Sat Apr 15 00:00:00 EDT 2017
SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.
Developmental biology
Zhao L,Arsenault M,Ng ET,Longmuss E,Chau TC,Hartwig S,Koopman P
Wed Mar 01 00:00:00 EST 2017
SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.
Developmental biology
Zhao L,Arsenault M,Ng ET,Longmuss E,Chau TC,Hartwig S,Koopman P
Wed Mar 01 00:00:00 EST 2017
A novel Cre-inducible knock-in ARL13B-tRFP fusion cilium reporter.
Genesis (New York, N.Y. : 2000)
Schmitz F,Burtscher I,Stauber M,Gossler A,Lickert H
Wed Nov 01 00:00:00 EDT 2017
A novel Cre-inducible knock-in ARL13B-tRFP fusion cilium reporter.
Genesis (New York, N.Y. : 2000)
Schmitz F,Burtscher I,Stauber M,Gossler A,Lickert H
Wed Nov 01 00:00:00 EDT 2017
Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders.
Journal of visualized experiments : JoVE
Gabriel E,Gopalakrishnan J
Fri Apr 14 00:00:00 EDT 2017
Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders.
Journal of visualized experiments : JoVE
Gabriel E,Gopalakrishnan J
Fri Apr 14 00:00:00 EDT 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 EDT 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 EDT 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 EDT 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 EDT 2017
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons.
Journal of neuroinflammation
Baek H,Shin HJ,Kim JJ,Shin N,Kim S,Yi MH,Zhang E,Hong J,Kang JW,Kim Y,Kim CS,Kim DW
Tue Sep 19 00:00:00 EDT 2017
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons.
Journal of neuroinflammation
Baek H,Shin HJ,Kim JJ,Shin N,Kim S,Yi MH,Zhang E,Hong J,Kang JW,Kim Y,Kim CS,Kim DW
Tue Sep 19 00:00:00 EDT 2017
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons.
Journal of neuroinflammation
Baek H,Shin HJ,Kim JJ,Shin N,Kim S,Yi MH,Zhang E,Hong J,Kang JW,Kim Y,Kim CS,Kim DW
Tue Sep 19 00:00:00 EDT 2017
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons.
Journal of neuroinflammation
Baek H,Shin HJ,Kim JJ,Shin N,Kim S,Yi MH,Zhang E,Hong J,Kang JW,Kim Y,Kim CS,Kim DW
Tue Sep 19 00:00:00 EDT 2017
Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons.
Journal of neuroinflammation
Baek H,Shin HJ,Kim JJ,Shin N,Kim S,Yi MH,Zhang E,Hong J,Kang JW,Kim Y,Kim CS,Kim DW
Tue Sep 19 00:00:00 EDT 2017
The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Sharif A,Yazigi H,Frederick JM,Baehr W
Fri Dec 29 00:00:00 EST 2017
The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Sharif A,Yazigi H,Frederick JM,Baehr W
Fri Dec 29 00:00:00 EST 2017
The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Sharif A,Yazigi H,Frederick JM,Baehr W
Fri Dec 29 00:00:00 EST 2017
The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Sharif A,Yazigi H,Frederick JM,Baehr W
Fri Dec 29 00:00:00 EST 2017
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation.
The Journal of biological chemistry
Roy K,Jerman S,Jozsef L,McNamara T,Onyekaba G,Sun Z,Marin EP
Fri Oct 27 00:00:00 EDT 2017
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation.
The Journal of biological chemistry
Roy K,Jerman S,Jozsef L,McNamara T,Onyekaba G,Sun Z,Marin EP
Fri Oct 27 00:00:00 EDT 2017
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation.
The Journal of biological chemistry
Roy K,Jerman S,Jozsef L,McNamara T,Onyekaba G,Sun Z,Marin EP
Fri Oct 27 00:00:00 EDT 2017
Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation.
The Journal of biological chemistry
Roy K,Jerman S,Jozsef L,McNamara T,Onyekaba G,Sun Z,Marin EP
Fri Oct 27 00:00:00 EDT 2017
Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.
Neural development
Rakotomamonjy J,Brunner M,Jüschke C,Zang K,Huang EJ,Reichardt LF,Chenn A
Mon May 08 00:00:00 EDT 2017
Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.
Neural development
Rakotomamonjy J,Brunner M,Jüschke C,Zang K,Huang EJ,Reichardt LF,Chenn A
Mon May 08 00:00:00 EDT 2017
Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling.
European cells & materials
Thompson CL,Plant JC,Wann AK,Bishop CL,Novak P,Mitchison HM,Beales PL,Chapple JP,Knight MM
Wed Sep 20 00:00:00 EDT 2017
Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia.
Cilia
Duran I,Taylor SP,Zhang W,Martin J,Qureshi F,Jacques SM,Wallerstein R,Lachman RS,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Wed Sep 30 00:00:00 EDT 2020
Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia.
Cilia
Duran I,Taylor SP,Zhang W,Martin J,Qureshi F,Jacques SM,Wallerstein R,Lachman RS,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Wed Sep 30 00:00:00 EDT 2020
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Scientific reports
Bizzotto S,Uzquiano A,Dingli F,Ershov D,Houllier A,Arras G,Richards M,Loew D,Minc N,Croquelois A,Houdusse A,Francis F
Mon Dec 11 00:00:00 EST 2017
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Scientific reports
Bizzotto S,Uzquiano A,Dingli F,Ershov D,Houllier A,Arras G,Richards M,Loew D,Minc N,Croquelois A,Houdusse A,Francis F
Mon Dec 11 00:00:00 EST 2017
Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation.
PloS one
Nagai T,Mizuno K
Wed Oct 04 00:00:00 EDT 2017
Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation.
PloS one
Nagai T,Mizuno K
Wed Oct 04 00:00:00 EDT 2017
An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.
Scientific reports
Stayner C,Poole CA,McGlashan SR,Pilanthananond M,Brauning R,Markie D,Lett B,Slobbe L,Chae A,Johnstone AC,Jensen CG,McEwan JC,Dittmer K,Parker K,Wiles A,Blackburne W,Leichter A,Leask M,Pinnapureddy A,Jennings M,Horsfield JA,Walker RJ,Eccles MR
Tue May 09 00:00:00 EDT 2017
An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.
Scientific reports
Stayner C,Poole CA,McGlashan SR,Pilanthananond M,Brauning R,Markie D,Lett B,Slobbe L,Chae A,Johnstone AC,Jensen CG,McEwan JC,Dittmer K,Parker K,Wiles A,Blackburne W,Leichter A,Leask M,Pinnapureddy A,Jennings M,Horsfield JA,Walker RJ,Eccles MR
Tue May 09 00:00:00 EDT 2017
Abnormal glycosylation in Joubert syndrome type 10.
Cilia
Kane MS,Davids M,Bond MR,Adams CJ,Grout ME,Phelps IG,O'Day DR,Dempsey JC,Li X,Golas G,Vezina G,Gunay-Aygun M,Hanover JA,Doherty D,He M,Malicdan MCV,Gahl WA,Boerkoel CF
Thu Oct 01 00:00:00 EDT 2020
Abnormal glycosylation in Joubert syndrome type 10.
Cilia
Kane MS,Davids M,Bond MR,Adams CJ,Grout ME,Phelps IG,O'Day DR,Dempsey JC,Li X,Golas G,Vezina G,Gunay-Aygun M,Hanover JA,Doherty D,He M,Malicdan MCV,Gahl WA,Boerkoel CF
Thu Oct 01 00:00:00 EDT 2020
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.
Nature communications
Taulet N,Vitre B,Anguille C,Douanier A,Rocancourt M,Taschner M,Lorentzen E,Echard A,Delaval B
Mon Dec 04 00:00:00 EST 2017
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.
Nature communications
Taulet N,Vitre B,Anguille C,Douanier A,Rocancourt M,Taschner M,Lorentzen E,Echard A,Delaval B
Mon Dec 04 00:00:00 EST 2017
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Nature communications
Schou KB,Mogensen JB,Morthorst SK,Nielsen BS,Aleliunaite A,Serra-Marques A,Fürstenberg N,Saunier S,Bizet AA,Veland IR,Akhmanova A,Christensen ST,Pedersen LB
Mon Jan 30 00:00:00 EST 2017
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Nature communications
Schou KB,Mogensen JB,Morthorst SK,Nielsen BS,Aleliunaite A,Serra-Marques A,Fürstenberg N,Saunier S,Bizet AA,Veland IR,Akhmanova A,Christensen ST,Pedersen LB
Mon Jan 30 00:00:00 EST 2017
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
Cell stem cell
Gabriel E,Ramani A,Karow U,Gottardo M,Natarajan K,Gooi LM,Goranci-Buzhala G,Krut O,Peters F,Nikolic M,Kuivanen S,Korhonen E,Smura T,Vapalahti O,Papantonis A,Schmidt-Chanasit J,Riparbelli M,Callaini G,Krönke M,Utermöhlen O,Gopalakrishnan J
Thu Mar 02 00:00:00 EST 2017
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
Cell stem cell
Gabriel E,Ramani A,Karow U,Gottardo M,Natarajan K,Gooi LM,Goranci-Buzhala G,Krut O,Peters F,Nikolic M,Kuivanen S,Korhonen E,Smura T,Vapalahti O,Papantonis A,Schmidt-Chanasit J,Riparbelli M,Callaini G,Krönke M,Utermöhlen O,Gopalakrishnan J
Thu Mar 02 00:00:00 EST 2017
Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice.
Genes, brain, and behavior
Wang B,Zheng Y,Shi H,Du X,Zhang Y,Wei B,Luo M,Wang H,Wu X,Hua X,Sun M,Xu X
Wed Feb 01 00:00:00 EST 2017
Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice.
Genes, brain, and behavior
Wang B,Zheng Y,Shi H,Du X,Zhang Y,Wei B,Luo M,Wang H,Wu X,Hua X,Sun M,Xu X
Wed Feb 01 00:00:00 EST 2017
Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.
PloS one
Grzelak CA,Sigglekow ND,Tirnitz-Parker JE,Hamson EJ,Warren A,Maneck B,Chen J,Patkunanathan B,Boland J,Cheng R,Shackel NA,Seth D,Bowen DG,Martelotto LG,Watkins DN,McCaughan GW
Wed Aug 09 00:00:00 EDT 2017
Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.
PloS one
Grzelak CA,Sigglekow ND,Tirnitz-Parker JE,Hamson EJ,Warren A,Maneck B,Chen J,Patkunanathan B,Boland J,Cheng R,Shackel NA,Seth D,Bowen DG,Martelotto LG,Watkins DN,McCaughan GW
Wed Aug 09 00:00:00 EDT 2017
Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
Human molecular genetics
Schwarz N,Lane A,Jovanovic K,Parfitt DA,Aguila M,Thompson CL,da Cruz L,Coffey PJ,Chapple JP,Hardcastle AJ,Cheetham ME
Sat Jul 01 00:00:00 EDT 2017
NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.
Cell research
Zhang C,Zhang W,Lu Y,Yan X,Yan X,Zhu X,Liu W,Yang Y,Zhou T
Mon Feb 01 00:00:00 EST 2016
Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex.
Nature neuroscience
Wang L,Hou S,Han YG
Fri Jul 01 00:00:00 EDT 2016
Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex.
Nature neuroscience
Wang L,Hou S,Han YG
Fri Jul 01 00:00:00 EDT 2016
TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.
Nature cell biology
Lambacher NJ,Bruel AL,van Dam TJ,Szymańska K,Slaats GG,Kuhns S,McManus GJ,Kennedy JE,Gaff K,Wu KM,van der Lee R,Burglen L,Doummar D,Rivière JB,Faivre L,Attié-Bitach T,Saunier S,Curd A,Peckham M,Giles RH,Johnson CA,Huynen MA,Thauvin-Robinet C,Blacque OE
Fri Jan 01 00:00:00 EST 2016
TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.
Nature cell biology
Lambacher NJ,Bruel AL,van Dam TJ,Szymańska K,Slaats GG,Kuhns S,McManus GJ,Kennedy JE,Gaff K,Wu KM,van der Lee R,Burglen L,Doummar D,Rivière JB,Faivre L,Attié-Bitach T,Saunier S,Curd A,Peckham M,Giles RH,Johnson CA,Huynen MA,Thauvin-Robinet C,Blacque OE
Fri Jan 01 00:00:00 EST 2016
Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.
Nature cell biology
Li L,Grausam KB,Wang J,Lun MP,Ohli J,Lidov HG,Calicchio ML,Zeng E,Salisbury JL,Wechsler-Reya RJ,Lehtinen MK,Schüller U,Zhao H
Fri Apr 01 00:00:00 EDT 2016
Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.
Nature cell biology
Li L,Grausam KB,Wang J,Lun MP,Ohli J,Lidov HG,Calicchio ML,Zeng E,Salisbury JL,Wechsler-Reya RJ,Lehtinen MK,Schüller U,Zhao H
Fri Apr 01 00:00:00 EDT 2016
Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups.
Cell stem cell
Parfitt DA,Lane A,Ramsden CM,Carr AF,Munro PM,Jovanovic K,Schwarz N,Kanuga N,Muthiah MN,Hull S,Gallo JM,da Cruz L,Moore AT,Hardcastle AJ,Coffey PJ,Cheetham ME
Thu Jun 02 00:00:00 EDT 2016
Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups.
Cell stem cell
Parfitt DA,Lane A,Ramsden CM,Carr AF,Munro PM,Jovanovic K,Schwarz N,Kanuga N,Muthiah MN,Hull S,Gallo JM,da Cruz L,Moore AT,Hardcastle AJ,Coffey PJ,Cheetham ME
Thu Jun 02 00:00:00 EDT 2016
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts.
Journal of the American Society of Nephrology : JASN
Li Y,Tian X,Ma M,Jerman S,Kong S,Somlo S,Sun Z
Thu Dec 01 00:00:00 EST 2016
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts.
Journal of the American Society of Nephrology : JASN
Li Y,Tian X,Ma M,Jerman S,Kong S,Somlo S,Sun Z
Thu Dec 01 00:00:00 EST 2016
CPAP promotes timely cilium disassembly to maintain neural progenitor pool.
The EMBO journal
Gabriel E,Wason A,Ramani A,Gooi LM,Keller P,Pozniakovsky A,Poser I,Noack F,Telugu NS,Calegari F,Šarić T,Hescheler J,Hyman AA,Gottardo M,Callaini G,Alkuraya FS,Gopalakrishnan J
Fri Apr 15 00:00:00 EDT 2016
CPAP promotes timely cilium disassembly to maintain neural progenitor pool.
The EMBO journal
Gabriel E,Wason A,Ramani A,Gooi LM,Keller P,Pozniakovsky A,Poser I,Noack F,Telugu NS,Calegari F,Šarić T,Hescheler J,Hyman AA,Gottardo M,Callaini G,Alkuraya FS,Gopalakrishnan J
Fri Apr 15 00:00:00 EDT 2016
Endothelial primary cilia inhibit atherosclerosis.
EMBO reports
Dinsmore C,Reiter JF
Mon Feb 01 00:00:00 EST 2016
Endothelial primary cilia inhibit atherosclerosis.
EMBO reports
Dinsmore C,Reiter JF
Mon Feb 01 00:00:00 EST 2016
Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.
EMBO reports
Sánchez A,Urrego D,Pardo LA
Sun May 01 00:00:00 EDT 2016
Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.
EMBO reports
Sánchez A,Urrego D,Pardo LA
Sun May 01 00:00:00 EDT 2016
Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis.
Development (Cambridge, England)
Yadav SP,Sharma NK,Liu C,Dong L,Li T,Swaroop A
Sun May 01 00:00:00 EDT 2016
Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis.
Development (Cambridge, England)
Yadav SP,Sharma NK,Liu C,Dong L,Li T,Swaroop A
Sun May 01 00:00:00 EDT 2016
MKS1 regulates ciliary INPP5E levels in Joubert syndrome.
Journal of medical genetics
Slaats GG,Isabella CR,Kroes HY,Dempsey JC,Gremmels H,Monroe GR,Phelps IG,Duran KJ,Adkins J,Kumar SA,Knutzen DM,Knoers NV,Mendelsohn NJ,Neubauer D,Mastroyianni SD,Vogt J,Worgan L,Karp N,Bowdin S,Glass IA,Parisi MA,Otto EA,Johnson CA,Hildebrandt F,van Haaften G,Giles RH,Doherty D
Fri Jan 01 00:00:00 EST 2016
MKS1 regulates ciliary INPP5E levels in Joubert syndrome.
Journal of medical genetics
Slaats GG,Isabella CR,Kroes HY,Dempsey JC,Gremmels H,Monroe GR,Phelps IG,Duran KJ,Adkins J,Kumar SA,Knutzen DM,Knoers NV,Mendelsohn NJ,Neubauer D,Mastroyianni SD,Vogt J,Worgan L,Karp N,Bowdin S,Glass IA,Parisi MA,Otto EA,Johnson CA,Hildebrandt F,van Haaften G,Giles RH,Doherty D
Fri Jan 01 00:00:00 EST 2016
MKS1 regulates ciliary INPP5E levels in Joubert syndrome.
Journal of medical genetics
Slaats GG,Isabella CR,Kroes HY,Dempsey JC,Gremmels H,Monroe GR,Phelps IG,Duran KJ,Adkins J,Kumar SA,Knutzen DM,Knoers NV,Mendelsohn NJ,Neubauer D,Mastroyianni SD,Vogt J,Worgan L,Karp N,Bowdin S,Glass IA,Parisi MA,Otto EA,Johnson CA,Hildebrandt F,van Haaften G,Giles RH,Doherty D
Fri Jan 01 00:00:00 EST 2016
MKS1 regulates ciliary INPP5E levels in Joubert syndrome.
Journal of medical genetics
Slaats GG,Isabella CR,Kroes HY,Dempsey JC,Gremmels H,Monroe GR,Phelps IG,Duran KJ,Adkins J,Kumar SA,Knutzen DM,Knoers NV,Mendelsohn NJ,Neubauer D,Mastroyianni SD,Vogt J,Worgan L,Karp N,Bowdin S,Glass IA,Parisi MA,Otto EA,Johnson CA,Hildebrandt F,van Haaften G,Giles RH,Doherty D
Fri Jan 01 00:00:00 EST 2016
Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Thompson CL,Wiles A,Poole CA,Knight MM
Mon Feb 01 00:00:00 EST 2016
Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Thompson CL,Wiles A,Poole CA,Knight MM
Mon Feb 01 00:00:00 EST 2016
Neonatal seizures induced by pentylenetetrazol or kainic acid disrupt primary cilia growth on developing mouse cortical neurons.
Experimental neurology
Parker AK,Le MM,Smith TS,Hoang-Minh LB,Atkinson EW,Ugartemendia G,Semple-Rowland S,Coleman JE,Sarkisian MR
Mon Aug 01 00:00:00 EDT 2016
Neonatal seizures induced by pentylenetetrazol or kainic acid disrupt primary cilia growth on developing mouse cortical neurons.
Experimental neurology
Parker AK,Le MM,Smith TS,Hoang-Minh LB,Atkinson EW,Ugartemendia G,Semple-Rowland S,Coleman JE,Sarkisian MR
Mon Aug 01 00:00:00 EDT 2016
Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens.
Journal of immunology (Baltimore, Md. : 1950)
Giridhar PV,Bell SM,Sridharan A,Rajavelu P,Kitzmiller JA,Na CL,Kofron M,Brandt EB,Ericksen M,Naren AP,Moon C,Khurana Hershey GK,Whitsett JA
Thu Dec 01 00:00:00 EST 2016
Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens.
Journal of immunology (Baltimore, Md. : 1950)
Giridhar PV,Bell SM,Sridharan A,Rajavelu P,Kitzmiller JA,Na CL,Kofron M,Brandt EB,Ericksen M,Naren AP,Moon C,Khurana Hershey GK,Whitsett JA
Thu Dec 01 00:00:00 EST 2016
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.
Journal of cell science
Kurtulmus B,Wang W,Ruppert T,Neuner A,Cerikan B,Viol L,Dueñas-Sánchez R,Gruss OJ,Pereira G
Mon Feb 01 00:00:00 EST 2016
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.
Journal of cell science
Kurtulmus B,Wang W,Ruppert T,Neuner A,Cerikan B,Viol L,Dueñas-Sánchez R,Gruss OJ,Pereira G
Mon Feb 01 00:00:00 EST 2016
IFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome.
Human molecular genetics
Zhang W,Taylor SP,Nevarez L,Lachman RS,Nickerson DA,Bamshad M,Krakow D,Cohn DH
Thu Sep 15 00:00:00 EDT 2016
IFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome.
Human molecular genetics
Zhang W,Taylor SP,Nevarez L,Lachman RS,Nickerson DA,Bamshad M,Krakow D,Cohn DH
Thu Sep 15 00:00:00 EDT 2016
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.
Human molecular genetics
Paige Taylor S,Kunova Bosakova M,Varecha M,Balek L,Barta T,Trantirek L,Jelinkova I,Duran I,Vesela I,Forlenza KN,Martin JH,Hampl A,Bamshad M,Nickerson D,Jaworski ML,Song J,Ko HW,Cohn DH,Krakow D,Krejci P
Thu Sep 15 00:00:00 EDT 2016
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.
Human molecular genetics
Paige Taylor S,Kunova Bosakova M,Varecha M,Balek L,Barta T,Trantirek L,Jelinkova I,Duran I,Vesela I,Forlenza KN,Martin JH,Hampl A,Bamshad M,Nickerson D,Jaworski ML,Song J,Ko HW,Cohn DH,Krakow D,Krejci P
Thu Sep 15 00:00:00 EDT 2016
Recessive NEK9 mutation causes a lethal skeletal dysplasia with evidence of cell cycle and ciliary defects.
Human molecular genetics
Casey JP,Brennan K,Scheidel N,McGettigan P,Lavin PT,Carter S,Ennis S,Dorkins H,Ghali N,Blacque OE,Mc Gee MM,Murphy H,Lynch SA
Sun May 01 00:00:00 EDT 2016
Recessive NEK9 mutation causes a lethal skeletal dysplasia with evidence of cell cycle and ciliary defects.
Human molecular genetics
Casey JP,Brennan K,Scheidel N,McGettigan P,Lavin PT,Carter S,Ennis S,Dorkins H,Ghali N,Blacque OE,Mc Gee MM,Murphy H,Lynch SA
Sun May 01 00:00:00 EDT 2016
Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish.
Investigative ophthalmology & visual science
Song P,Dudinsky L,Fogerty J,Gaivin R,Perkins BD
Mon Aug 01 00:00:00 EDT 2016
Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish.
Investigative ophthalmology & visual science
Song P,Dudinsky L,Fogerty J,Gaivin R,Perkins BD
Mon Aug 01 00:00:00 EDT 2016
Neuroanatomical characterization of the cellular and axonal architecture of subcortical band heterotopia in the BXD29-Tlr4lps-2J/J mouse cortex.
Neuroscience
Ramos RL,Toia AR,Pasternack DM,Dotzler TP,Cuoco JA,Esposito AW,Le MM,Parker AK,Goodman JH,Sarkisian MR
Sat Nov 19 00:00:00 EST 2016
Neuroanatomical characterization of the cellular and axonal architecture of subcortical band heterotopia in the BXD29-Tlr4lps-2J/J mouse cortex.
Neuroscience
Ramos RL,Toia AR,Pasternack DM,Dotzler TP,Cuoco JA,Esposito AW,Le MM,Parker AK,Goodman JH,Sarkisian MR
Sat Nov 19 00:00:00 EST 2016
Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC
Fri Jan 15 00:00:00 EST 2016
Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC
Fri Jan 15 00:00:00 EST 2016
Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC
Fri Jan 15 00:00:00 EST 2016
Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC
Fri Jan 15 00:00:00 EST 2016
RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner.
Biology open
Dutta N,Seo S
Thu Sep 15 00:00:00 EDT 2016
RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner.
Biology open
Dutta N,Seo S
Thu Sep 15 00:00:00 EDT 2016
Immunofluorescent staining of septins in primary cilia.
Methods in cell biology
Kim MS,Froese CD,Xie H,Trimble WS
Mon Aug 21 00:00:00 EDT 2017
Immunofluorescent staining of septins in primary cilia.
Methods in cell biology
Kim MS,Froese CD,Xie H,Trimble WS
Mon Aug 21 00:00:00 EDT 2017
Targeting of ASH Domain-Containing Proteins to the Centrosome.
Methods in molecular biology (Clifton, N.J.)
Verdier P,Morthorst SK,Pedersen LB
Fri Jan 12 00:00:00 EST 2018
Nestin Mediates Hedgehog Pathway Tumorigenesis.
Cancer research
Li P,Lee EH,Du F,Gordon RE,Yuelling LW,Liu Y,Ng JM,Zhang H,Wu J,Korshunov A,Pfister SM,Curran T,Yang ZJ
Thu Sep 15 00:00:00 EDT 2016
Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy.
Oncotarget
Lee J,Yi S,Kang YE,Chang JY,Kim JT,Sul HJ,Kim JO,Kim JM,Kim J,Porcelli AM,Kim KS,Shong M
Tue Nov 29 00:00:00 EST 2016
Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy.
Oncotarget
Lee J,Yi S,Kang YE,Chang JY,Kim JT,Sul HJ,Kim JO,Kim JM,Kim J,Porcelli AM,Kim KS,Shong M
Tue Nov 29 00:00:00 EST 2016
Prenylated retinal ciliopathy protein RPGR interacts with PDE6δ and regulates ciliary localization of Joubert syndrome-associated protein INPP5E.
Human molecular genetics
Rao KN,Zhang W,Li L,Anand M,Khanna H
Sat Oct 15 00:00:00 EDT 2016
Primary Cilia Negatively Regulate Melanogenesis in Melanocytes and Pigmentation in a Human Skin Model.
PloS one
Choi H,Shin JH,Kim ES,Park SJ,Bae IH,Jo YK,Jeong IY,Kim HJ,Lee Y,Park HC,Jeon HB,Kim KW,Lee TR,Cho DH
Wed Jun 28 00:00:00 EDT 2017
Primary Cilia Negatively Regulate Melanogenesis in Melanocytes and Pigmentation in a Human Skin Model.
PloS one
Choi H,Shin JH,Kim ES,Park SJ,Bae IH,Jo YK,Jeong IY,Kim HJ,Lee Y,Park HC,Jeon HB,Kim KW,Lee TR,Cho DH
Wed Jun 28 00:00:00 EDT 2017
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R
Fri May 13 00:00:00 EDT 2016
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R
Fri May 13 00:00:00 EDT 2016
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.
Nature communications
Doobin DJ,Kemal S,Dantas TJ,Vallee RB
Wed Aug 24 00:00:00 EDT 2016
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.
Nature communications
Doobin DJ,Kemal S,Dantas TJ,Vallee RB
Wed Aug 24 00:00:00 EDT 2016
A novel ICK mutation causes ciliary disruption and lethal endocrine-cerebro-osteodysplasia syndrome.
Cilia
Oud MM,Bonnard C,Mans DA,Altunoglu U,Tohari S,Ng AYJ,Eskin A,Lee H,Rupar CA,de Wagenaar NP,Wu KM,Lahiry P,Pazour GJ,Nelson SF,Hegele RA,Roepman R,Kayserili H,Venkatesh B,Siu VM,Reversade B,Arts HH
Tue Apr 12 00:00:00 EDT 2016
A novel ICK mutation causes ciliary disruption and lethal endocrine-cerebro-osteodysplasia syndrome.
Cilia
Oud MM,Bonnard C,Mans DA,Altunoglu U,Tohari S,Ng AYJ,Eskin A,Lee H,Rupar CA,de Wagenaar NP,Wu KM,Lahiry P,Pazour GJ,Nelson SF,Hegele RA,Roepman R,Kayserili H,Venkatesh B,Siu VM,Reversade B,Arts HH
Tue Apr 12 00:00:00 EDT 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Cell reports
Fu W,Wang L,Kim S,Li J,Dynlacht BD
Tue Nov 01 00:00:00 EDT 2016
Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy.
Methods in molecular biology (Clifton, N.J.)
Ghossoub R,Lindbæk L,Molla-Herman A,Schmitt A,Christensen ST,Benmerah A
Fri Jan 12 00:00:00 EST 2018
Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy.
Methods in molecular biology (Clifton, N.J.)
Ghossoub R,Lindbæk L,Molla-Herman A,Schmitt A,Christensen ST,Benmerah A
Fri Jan 12 00:00:00 EST 2018
KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer.
Scientific reports
Kim M,Suh YA,Oh JH,Lee BR,Kim J,Jang SJ
Tue Sep 06 00:00:00 EDT 2016
KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer.
Scientific reports
Kim M,Suh YA,Oh JH,Lee BR,Kim J,Jang SJ
Tue Sep 06 00:00:00 EDT 2016
MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.
Scientific reports
Lee SH,Lee MS,Choi TI,Hong H,Seo JY,Kim CH,Kim J
Mon Jun 06 00:00:00 EDT 2016
MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.
Scientific reports
Lee SH,Lee MS,Choi TI,Hong H,Seo JY,Kim CH,Kim J
Mon Jun 06 00:00:00 EDT 2016
Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.
PLoS genetics
Chang CF,Chang YT,Millington G,Brugmann SA
Tue Nov 01 00:00:00 EDT 2016
Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.
PLoS genetics
Chang CF,Chang YT,Millington G,Brugmann SA
Tue Nov 01 00:00:00 EDT 2016
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
PLoS genetics
Hong CJ,Hamilton BA
Sat Oct 01 00:00:00 EDT 2016
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
PLoS genetics
Hong CJ,Hamilton BA
Sat Oct 01 00:00:00 EDT 2016
Methods for Visualization of Neuronal Cilia.
Methods in molecular biology (Clifton, N.J.)
Caspary T,Marazziti D,Berbari NF
Fri Jan 12 00:00:00 EST 2018
Methods for Visualization of Neuronal Cilia.
Methods in molecular biology (Clifton, N.J.)
Caspary T,Marazziti D,Berbari NF
Fri Jan 12 00:00:00 EST 2018
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.
Scientific reports
Duran I,Taylor SP,Zhang W,Martin J,Forlenza KN,Spiro RP,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Mon Sep 26 00:00:00 EDT 2016
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.
Scientific reports
Duran I,Taylor SP,Zhang W,Martin J,Forlenza KN,Spiro RP,Nickerson DA,Bamshad M,Cohn DH,Krakow D
Mon Sep 26 00:00:00 EDT 2016
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.
Oncotarget
Hoang-Minh LB,Deleyrolle LP,Siebzehnrubl D,Ugartemendia G,Futch H,Griffith B,Breunig JJ,De Leon G,Mitchell DA,Semple-Rowland S,Reynolds BA,Sarkisian MR
Tue Feb 09 00:00:00 EST 2016
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.
Oncotarget
Hoang-Minh LB,Deleyrolle LP,Siebzehnrubl D,Ugartemendia G,Futch H,Griffith B,Breunig JJ,De Leon G,Mitchell DA,Semple-Rowland S,Reynolds BA,Sarkisian MR
Tue Feb 09 00:00:00 EST 2016
Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Gerstner CD,Frederick JM,Zhang H,Baehr W
Fri Mar 25 00:00:00 EDT 2016
Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Gerstner CD,Frederick JM,Zhang H,Baehr W
Fri Mar 25 00:00:00 EDT 2016
Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Gerstner CD,Frederick JM,Zhang H,Baehr W
Fri Mar 25 00:00:00 EDT 2016
Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
The Journal of biological chemistry
Hanke-Gogokhia C,Wu Z,Gerstner CD,Frederick JM,Zhang H,Baehr W
Fri Mar 25 00:00:00 EDT 2016
Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina.
Cell reports
May-Simera HL,Gumerson JD,Gao C,Campos M,Cologna SM,Beyer T,Boldt K,Kaya KD,Patel N,Kretschmer F,Kelley MW,Petralia RS,Davey MG,Li T
Tue Oct 25 00:00:00 EDT 2016
Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina.
Cell reports
May-Simera HL,Gumerson JD,Gao C,Campos M,Cologna SM,Beyer T,Boldt K,Kaya KD,Patel N,Kretschmer F,Kelley MW,Petralia RS,Davey MG,Li T
Tue Oct 25 00:00:00 EDT 2016
Measuring the primary cilium length: improved method for unbiased high-throughput analysis.
Cilia
Dummer A,Poelma C,DeRuiter MC,Goumans MJ,Hierck BP
Fri Feb 12 00:00:00 EST 2016
Measuring the primary cilium length: improved method for unbiased high-throughput analysis.
Cilia
Dummer A,Poelma C,DeRuiter MC,Goumans MJ,Hierck BP
Fri Feb 12 00:00:00 EST 2016
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.
Nature cell biology
Wheway G,Schmidts M,Mans DA,Szymanska K,Nguyen TT,Racher H,Phelps IG,Toedt G,Kennedy J,Wunderlich KA,Sorusch N,Abdelhamed ZA,Natarajan S,Herridge W,van Reeuwijk J,Horn N,Boldt K,Parry DA,Letteboer SJF,Roosing S,Adams M,Bell SM,Bond J,Higgins J,Morrison EE,Tomlinson DC,Slaats GG,van Dam TJP,Huang L,Kessler K,Giessl A,Logan CV,Boyle EA,Shendure J,Anazi S,Aldahmesh M,Al Hazzaa S,Hegele RA,Ober C,Frosk P,Mhanni AA,Chodirker BN,Chudley AE,Lamont R,Bernier FP,Beaulieu CL,Gordon P,Pon RT,Donahue C,Barkovich AJ,Wolf L,Toomes C,Thiel CT,Boycott KM,McKibbin M,Inglehearn CF,Stewart F,Omran H,Huynen MA,Sergouniotis PI,Alkuraya FS,Parboosingh JS,Innes AM,Willoughby CE,Giles RH,Webster AR,Ueffing M,Blacque O,Gleeson JG,Wolfrum U,Beales PL,Gibson T,Doherty D,Mitchison HM,Roepman R,Johnson CA
Sat Aug 01 00:00:00 EDT 2015
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.
Nature cell biology
Wheway G,Schmidts M,Mans DA,Szymanska K,Nguyen TT,Racher H,Phelps IG,Toedt G,Kennedy J,Wunderlich KA,Sorusch N,Abdelhamed ZA,Natarajan S,Herridge W,van Reeuwijk J,Horn N,Boldt K,Parry DA,Letteboer SJF,Roosing S,Adams M,Bell SM,Bond J,Higgins J,Morrison EE,Tomlinson DC,Slaats GG,van Dam TJP,Huang L,Kessler K,Giessl A,Logan CV,Boyle EA,Shendure J,Anazi S,Aldahmesh M,Al Hazzaa S,Hegele RA,Ober C,Frosk P,Mhanni AA,Chodirker BN,Chudley AE,Lamont R,Bernier FP,Beaulieu CL,Gordon P,Pon RT,Donahue C,Barkovich AJ,Wolf L,Toomes C,Thiel CT,Boycott KM,McKibbin M,Inglehearn CF,Stewart F,Omran H,Huynen MA,Sergouniotis PI,Alkuraya FS,Parboosingh JS,Innes AM,Willoughby CE,Giles RH,Webster AR,Ueffing M,Blacque O,Gleeson JG,Wolfrum U,Beales PL,Gibson T,Doherty D,Mitchison HM,Roepman R,Johnson CA
Sat Aug 01 00:00:00 EDT 2015
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
The Journal of clinical investigation
Gainullin VG,Hopp K,Ward CJ,Hommerding CJ,Harris PC
Sun Feb 01 00:00:00 EST 2015
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
The Journal of clinical investigation
Gainullin VG,Hopp K,Ward CJ,Hommerding CJ,Harris PC
Sun Feb 01 00:00:00 EST 2015
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Proceedings of the National Academy of Sciences of the United States of America
Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S
Tue Aug 11 00:00:00 EDT 2015
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Proceedings of the National Academy of Sciences of the United States of America
Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S
Tue Aug 11 00:00:00 EDT 2015
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Proceedings of the National Academy of Sciences of the United States of America
Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S
Tue Aug 11 00:00:00 EDT 2015
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Proceedings of the National Academy of Sciences of the United States of America
Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S
Tue Aug 11 00:00:00 EDT 2015
Centrin2 regulates CP110 removal in primary cilium formation.
The Journal of cell biology
Prosser SL,Morrison CG
Mon Mar 16 00:00:00 EDT 2015
Centrin2 regulates CP110 removal in primary cilium formation.
The Journal of cell biology
Prosser SL,Morrison CG
Mon Mar 16 00:00:00 EDT 2015
Loss of primary cilia in melanoma cells is likely independent of proliferation and cell cycle progression.
The Journal of investigative dermatology
Snedecor ER,Sung CC,Moncayo A,Rothstein BE,Mockler DC,Tonnesen MG,Jones EC,Fujita M,Clark RA,Shroyer KR,Chen J
Fri May 01 00:00:00 EDT 2015
Loss of primary cilia in melanoma cells is likely independent of proliferation and cell cycle progression.
The Journal of investigative dermatology
Snedecor ER,Sung CC,Moncayo A,Rothstein BE,Mockler DC,Tonnesen MG,Jones EC,Fujita M,Clark RA,Shroyer KR,Chen J
Fri May 01 00:00:00 EDT 2015
Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Joiner AM,Green WW,McIntyre JC,Allen BL,Schwob JE,Martens JR
Wed Oct 07 00:00:00 EDT 2015
Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Joiner AM,Green WW,McIntyre JC,Allen BL,Schwob JE,Martens JR
Wed Oct 07 00:00:00 EDT 2015
Mutations in human homologue of chicken talpid3 gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes.
Journal of medical genetics
Malicdan MC,Vilboux T,Stephen J,Maglic D,Mian L,Konzman D,Guo J,Yildirimli D,Bryant J,Fischer R,Zein WM,Snow J,Vemulapalli M,Mullikin JC,Toro C,Solomon BD,Niederhuber JE,Gahl WA,Gunay-Aygun M
Tue Dec 01 00:00:00 EST 2015
Mutations in human homologue of chicken talpid3 gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes.
Journal of medical genetics
Malicdan MC,Vilboux T,Stephen J,Maglic D,Mian L,Konzman D,Guo J,Yildirimli D,Bryant J,Fischer R,Zein WM,Snow J,Vemulapalli M,Mullikin JC,Toro C,Solomon BD,Niederhuber JE,Gahl WA,Gunay-Aygun M
Tue Dec 01 00:00:00 EST 2015
The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Structure (London, England : 1993)
Lokaj M,Kösling SK,Koerner C,Lange SM,van Beersum SE,van Reeuwijk J,Roepman R,Horn N,Ueffing M,Boldt K,Wittinghofer A
Tue Nov 03 00:00:00 EST 2015
The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Structure (London, England : 1993)
Lokaj M,Kösling SK,Koerner C,Lange SM,van Beersum SE,van Reeuwijk J,Roepman R,Horn N,Ueffing M,Boldt K,Wittinghofer A
Tue Nov 03 00:00:00 EST 2015
The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.
Journal of cell science
Carpenter BS,Barry RL,Verhey KJ,Allen BL
Sun Mar 01 00:00:00 EST 2015
The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.
Journal of cell science
Carpenter BS,Barry RL,Verhey KJ,Allen BL
Sun Mar 01 00:00:00 EST 2015
PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism.
Journal of cell science
Nielsen BS,Malinda RR,Schmid FM,Pedersen SF,Christensen ST,Pedersen LB
Thu Oct 01 00:00:00 EDT 2015
PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism.
Journal of cell science
Nielsen BS,Malinda RR,Schmid FM,Pedersen SF,Christensen ST,Pedersen LB
Thu Oct 01 00:00:00 EDT 2015
A role for Rab23 in the trafficking of Kif17 to the primary cilium.
Journal of cell science
Lim YS,Tang BL
Sat Aug 15 00:00:00 EDT 2015
A role for Rab23 in the trafficking of Kif17 to the primary cilium.
Journal of cell science
Lim YS,Tang BL
Sat Aug 15 00:00:00 EDT 2015
Cell Cycle-Dependent Localization of Dynactin Subunit p150 glued at Centrosome.
Journal of cellular biochemistry
Chen TY,Syu JS,Han TY,Cheng HL,Lu FI,Wang CY
Tue Sep 01 00:00:00 EDT 2015
Cell Cycle-Dependent Localization of Dynactin Subunit p150 glued at Centrosome.
Journal of cellular biochemistry
Chen TY,Syu JS,Han TY,Cheng HL,Lu FI,Wang CY
Tue Sep 01 00:00:00 EDT 2015
Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
Biochemical and biophysical research communications
Hong H,Kim J,Kim J
Fri May 22 00:00:00 EDT 2015
Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
Biochemical and biophysical research communications
Hong H,Kim J,Kim J
Fri May 22 00:00:00 EDT 2015
A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.
Developmental biology
Lu H,Toh MT,Narasimhan V,Thamilselvam SK,Choksi SP,Roy S
Thu Jan 15 00:00:00 EST 2015
A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.
Developmental biology
Lu H,Toh MT,Narasimhan V,Thamilselvam SK,Choksi SP,Roy S
Thu Jan 15 00:00:00 EST 2015
Imaging centrosomes and cilia in the mouse kidney.
Methods in cell biology
Hoshi M,Wang J,Jain S,Mahjoub MR
Tue Jan 26 00:00:00 EST 2016
Imaging centrosomes and cilia in the mouse kidney.
Methods in cell biology
Hoshi M,Wang J,Jain S,Mahjoub MR
Tue Jan 26 00:00:00 EST 2016
Analysis of primary cilia in the developing mouse brain.
Methods in cell biology
Paridaen JT,Huttner WB,Wilsch-Bräuninger M
Tue Jan 26 00:00:00 EST 2016
Analysis of primary cilia in the developing mouse brain.
Methods in cell biology
Paridaen JT,Huttner WB,Wilsch-Bräuninger M
Tue Jan 26 00:00:00 EST 2016
Analysis of primary cilia in the developing mouse brain.
Methods in cell biology
Paridaen JT,Huttner WB,Wilsch-Bräuninger M
Tue Jan 26 00:00:00 EST 2016
Analysis of primary cilia in the developing mouse brain.
Methods in cell biology
Paridaen JT,Huttner WB,Wilsch-Bräuninger M
Tue Jan 26 00:00:00 EST 2016
Non-Overlapping Distributions and Functions of the VDAC Family in Ciliogenesis.
Cells
Majumder S,Cash A,Fisk HA
Fri Jul 31 00:00:00 EDT 2015
Non-Overlapping Distributions and Functions of the VDAC Family in Ciliogenesis.
Cells
Majumder S,Cash A,Fisk HA
Fri Jul 31 00:00:00 EDT 2015
Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition.
Scientific reports
Rao KN,Li L,Anand M,Khanna H
Thu Jun 11 00:00:00 EDT 2015
Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition.
Scientific reports
Rao KN,Li L,Anand M,Khanna H
Thu Jun 11 00:00:00 EDT 2015
Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome.
Nature communications
Taylor SP,Dantas TJ,Duran I,Wu S,Lachman RS,Nelson SF,Cohn DH,Vallee RB,Krakow D
Tue Jun 16 00:00:00 EDT 2015
Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome.
Nature communications
Taylor SP,Dantas TJ,Duran I,Wu S,Lachman RS,Nelson SF,Cohn DH,Vallee RB,Krakow D
Tue Jun 16 00:00:00 EDT 2015
The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation.
Cell reports
Miyamoto T,Hosoba K,Ochiai H,Royba E,Izumi H,Sakuma T,Yamamoto T,Dynlacht BD,Matsuura S
Tue Feb 10 00:00:00 EST 2015
The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation.
Cell reports
Miyamoto T,Hosoba K,Ochiai H,Royba E,Izumi H,Sakuma T,Yamamoto T,Dynlacht BD,Matsuura S
Tue Feb 10 00:00:00 EST 2015
The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels.
The Journal of biological chemistry
Singh J,Wen X,Scales SJ
Fri Dec 04 00:00:00 EST 2015
The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels.
The Journal of biological chemistry
Singh J,Wen X,Scales SJ
Fri Dec 04 00:00:00 EST 2015
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation.
PloS one
Jiang S,Du J,Kong Q,Li C,Li Y,Sun H,Pu J,Mao B
Wed Jun 01 00:00:00 EDT 2016
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation.
PloS one
Jiang S,Du J,Kong Q,Li C,Li Y,Sun H,Pu J,Mao B
Wed Jun 01 00:00:00 EDT 2016
Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.
Nature communications
Bizet AA,Becker-Heck A,Ryan R,Weber K,Filhol E,Krug P,Halbritter J,Delous M,Lasbennes MC,Linghu B,Oakeley EJ,Zarhrate M,Nitschké P,Garfa-Traore M,Serluca F,Yang F,Bouwmeester T,Pinson L,Cassuto E,Dubot P,Elshakhs NAS,Sahel JA,Salomon R,Drummond IA,Gubler MC,Antignac C,Chibout S,Szustakowski JD,Hildebrandt F,Lorentzen E,Sailer AW,Benmerah A,Saint-Mezard P,Saunier S
Wed Oct 21 00:00:00 EDT 2015
Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.
Nature communications
Bizet AA,Becker-Heck A,Ryan R,Weber K,Filhol E,Krug P,Halbritter J,Delous M,Lasbennes MC,Linghu B,Oakeley EJ,Zarhrate M,Nitschké P,Garfa-Traore M,Serluca F,Yang F,Bouwmeester T,Pinson L,Cassuto E,Dubot P,Elshakhs NAS,Sahel JA,Salomon R,Drummond IA,Gubler MC,Antignac C,Chibout S,Szustakowski JD,Hildebrandt F,Lorentzen E,Sailer AW,Benmerah A,Saint-Mezard P,Saunier S
Wed Oct 21 00:00:00 EDT 2015
Culture and detection of primary cilia in endothelial cell models.
Cilia
Lim YC,McGlashan SR,Cooling MT,Long DS
Fri Oct 02 00:00:00 EDT 2015
Culture and detection of primary cilia in endothelial cell models.
Cilia
Lim YC,McGlashan SR,Cooling MT,Long DS
Fri Oct 02 00:00:00 EDT 2015
Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells.
Scientific reports
Nygaard MB,Almstrup K,Lindbæk L,Christensen ST,Svingen T
Wed May 20 00:00:00 EDT 2015
Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells.
Scientific reports
Nygaard MB,Almstrup K,Lindbæk L,Christensen ST,Svingen T
Wed May 20 00:00:00 EDT 2015
Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.
PLoS genetics
Yee LE,Garcia-Gonzalo FR,Bowie RV,Li C,Kennedy JK,Ashrafi K,Blacque OE,Leroux MR,Reiter JF
Sun Nov 01 00:00:00 EDT 2015
Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.
PLoS genetics
Yee LE,Garcia-Gonzalo FR,Bowie RV,Li C,Kennedy JK,Ashrafi K,Blacque OE,Leroux MR,Reiter JF
Sun Nov 01 00:00:00 EDT 2015
Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.
Cell metabolism
Stratigopoulos G,Martin Carli JF,O'Day DR,Wang L,Leduc CA,Lanzano P,Chung WK,Rosenbaum M,Egli D,Doherty DA,Leibel RL
Tue May 06 00:00:00 EDT 2014
Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.
Cell metabolism
Stratigopoulos G,Martin Carli JF,O'Day DR,Wang L,Leduc CA,Lanzano P,Chung WK,Rosenbaum M,Egli D,Doherty DA,Leibel RL
Tue May 06 00:00:00 EDT 2014
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Nature cell biology
Jin D,Ni TT,Sun J,Wan H,Amack JD,Yu G,Fleming J,Chiang C,Li W,Papierniak A,Cheepala S,Conseil G,Cole SP,Zhou B,Drummond IA,Schuetz JD,Malicki J,Zhong TP
Mon Sep 01 00:00:00 EDT 2014
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Nature cell biology
Jin D,Ni TT,Sun J,Wan H,Amack JD,Yu G,Fleming J,Chiang C,Li W,Papierniak A,Cheepala S,Conseil G,Cole SP,Zhou B,Drummond IA,Schuetz JD,Malicki J,Zhong TP
Mon Sep 01 00:00:00 EDT 2014
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Nature cell biology
Jin D,Ni TT,Sun J,Wan H,Amack JD,Yu G,Fleming J,Chiang C,Li W,Papierniak A,Cheepala S,Conseil G,Cole SP,Zhou B,Drummond IA,Schuetz JD,Malicki J,Zhong TP
Mon Sep 01 00:00:00 EDT 2014
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Nature cell biology
Jin D,Ni TT,Sun J,Wan H,Amack JD,Yu G,Fleming J,Chiang C,Li W,Papierniak A,Cheepala S,Conseil G,Cole SP,Zhou B,Drummond IA,Schuetz JD,Malicki J,Zhong TP
Mon Sep 01 00:00:00 EDT 2014
A homozygous missense mutation in the ciliary gene TTC21B causes familial FSGS.
Journal of the American Society of Nephrology : JASN
Huynh Cong E,Bizet AA,Boyer O,Woerner S,Gribouval O,Filhol E,Arrondel C,Thomas S,Silbermann F,Canaud G,Hachicha J,Ben Dhia N,Peraldi MN,Harzallah K,Iftene D,Daniel L,Willems M,Noel LH,Bole-Feysot C,Nitschké P,Gubler MC,Mollet G,Saunier S,Antignac C
Sat Nov 01 00:00:00 EDT 2014
A homozygous missense mutation in the ciliary gene TTC21B causes familial FSGS.
Journal of the American Society of Nephrology : JASN
Huynh Cong E,Bizet AA,Boyer O,Woerner S,Gribouval O,Filhol E,Arrondel C,Thomas S,Silbermann F,Canaud G,Hachicha J,Ben Dhia N,Peraldi MN,Harzallah K,Iftene D,Daniel L,Willems M,Noel LH,Bole-Feysot C,Nitschké P,Gubler MC,Mollet G,Saunier S,Antignac C
Sat Nov 01 00:00:00 EDT 2014
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
The EMBO journal
Chaya T,Omori Y,Kuwahara R,Furukawa T
Mon Jun 02 00:00:00 EDT 2014
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
The EMBO journal
Chaya T,Omori Y,Kuwahara R,Furukawa T
Mon Jun 02 00:00:00 EDT 2014
Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Čajánek L,Nigg EA
Tue Jul 15 00:00:00 EDT 2014
Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Čajánek L,Nigg EA
Tue Jul 15 00:00:00 EDT 2014
Arhgap36-dependent activation of Gli transcription factors.
Proceedings of the National Academy of Sciences of the United States of America
Rack PG,Ni J,Payumo AY,Nguyen V,Crapster JA,Hovestadt V,Kool M,Jones DT,Mich JK,Firestone AJ,Pfister SM,Cho YJ,Chen JK
Tue Jul 29 00:00:00 EDT 2014
Arhgap36-dependent activation of Gli transcription factors.
Proceedings of the National Academy of Sciences of the United States of America
Rack PG,Ni J,Payumo AY,Nguyen V,Crapster JA,Hovestadt V,Kool M,Jones DT,Mich JK,Firestone AJ,Pfister SM,Cho YJ,Chen JK
Tue Jul 29 00:00:00 EDT 2014
Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy.
American journal of human genetics
Roosing S,Lamers IJ,de Vrieze E,van den Born LI,Lambertus S,Arts HH,Peters TA,Hoyng CB,Kremer H,Hetterschijt L,Letteboer SJ,van Wijk E,Roepman R,den Hollander AI,Cremers FP
Thu Aug 07 00:00:00 EDT 2014
Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy.
American journal of human genetics
Roosing S,Lamers IJ,de Vrieze E,van den Born LI,Lambertus S,Arts HH,Peters TA,Hoyng CB,Kremer H,Hetterschijt L,Letteboer SJ,van Wijk E,Roepman R,den Hollander AI,Cremers FP
Thu Aug 07 00:00:00 EDT 2014
Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles.
The Journal of cell biology
Kong D,Farmer V,Shukla A,James J,Gruskin R,Kiriyama S,Loncarek J
Mon Sep 29 00:00:00 EDT 2014
Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles.
The Journal of cell biology
Kong D,Farmer V,Shukla A,James J,Gruskin R,Kiriyama S,Loncarek J
Mon Sep 29 00:00:00 EDT 2014
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes.
Osteoarthritis and cartilage
Thompson CL,Chapple JP,Knight MM
Sat Mar 01 00:00:00 EST 2014
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes.
Osteoarthritis and cartilage
Thompson CL,Chapple JP,Knight MM
Sat Mar 01 00:00:00 EST 2014
Basal body proteins regulate Notch signaling through endosomal trafficking.
Journal of cell science
Leitch CC,Lodh S,Prieto-Echagüe V,Badano JL,Zaghloul NA
Sun Jun 01 00:00:00 EDT 2014
Basal body proteins regulate Notch signaling through endosomal trafficking.
Journal of cell science
Leitch CC,Lodh S,Prieto-Echagüe V,Badano JL,Zaghloul NA
Sun Jun 01 00:00:00 EDT 2014
SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Human molecular genetics
Zhou X,Fan LX,Li K,Ramchandran R,Calvet JP,Li X
Sat Mar 15 00:00:00 EDT 2014
SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Human molecular genetics
Zhou X,Fan LX,Li K,Ramchandran R,Calvet JP,Li X
Sat Mar 15 00:00:00 EDT 2014
Primary cilia in the developing pig testis.
Cell and tissue research
Ou Y,Dores C,Rodriguez-Sosa JR,van der Hoorn FA,Dobrinski I
Sat Nov 01 00:00:00 EDT 2014
Primary cilia in the developing pig testis.
Cell and tissue research
Ou Y,Dores C,Rodriguez-Sosa JR,van der Hoorn FA,Dobrinski I
Sat Nov 01 00:00:00 EDT 2014
Primary cilia in the developing pig testis.
Cell and tissue research
Ou Y,Dores C,Rodriguez-Sosa JR,van der Hoorn FA,Dobrinski I
Sat Nov 01 00:00:00 EDT 2014
Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion.
Molecular biology of the cell
Aguilar A,Becker L,Tedeschi T,Heller S,Iomini C,Nachury MV
Sun Jun 15 00:00:00 EDT 2014
Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion.
Molecular biology of the cell
Aguilar A,Becker L,Tedeschi T,Heller S,Iomini C,Nachury MV
Sun Jun 15 00:00:00 EDT 2014
RFX7 is required for the formation of cilia in the neural tube.
Mechanisms of development
Manojlovic Z,Earwood R,Kato A,Stefanovic B,Kato Y
Thu May 01 00:00:00 EDT 2014
RFX7 is required for the formation of cilia in the neural tube.
Mechanisms of development
Manojlovic Z,Earwood R,Kato A,Stefanovic B,Kato Y
Thu May 01 00:00:00 EDT 2014
The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium.
eLife
Wang W,Wu T,Kirschner MW
Tue Aug 19 00:00:00 EDT 2014
The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium.
eLife
Wang W,Wu T,Kirschner MW
Tue Aug 19 00:00:00 EDT 2014
A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
PLoS genetics
Swiderski RE,Nakano Y,Mullins RF,Seo S,Bánfi B
Wed Oct 01 00:00:00 EDT 2014
A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling.
PLoS genetics
Swiderski RE,Nakano Y,Mullins RF,Seo S,Bánfi B
Wed Oct 01 00:00:00 EDT 2014
BBS4 is necessary for ciliary localization of TrkB receptor and activation by BDNF.
PloS one
Leitch CC,Zaghloul NA
Thu Aug 13 00:00:00 EDT 2015
BBS4 is necessary for ciliary localization of TrkB receptor and activation by BDNF.
PloS one
Leitch CC,Zaghloul NA
Thu Aug 13 00:00:00 EDT 2015
Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.
Nature communications
Veleri S,Manjunath SH,Fariss RN,May-Simera H,Brooks M,Foskett TA,Gao C,Longo TA,Liu P,Nagashima K,Rachel RA,Li T,Dong L,Swaroop A
Fri Jun 20 00:00:00 EDT 2014
Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.
Nature communications
Veleri S,Manjunath SH,Fariss RN,May-Simera H,Brooks M,Foskett TA,Gao C,Longo TA,Liu P,Nagashima K,Rachel RA,Li T,Dong L,Swaroop A
Fri Jun 20 00:00:00 EDT 2014
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.
Nature communications
Kim H,Xu H,Yao Q,Li W,Huang Q,Outeda P,Cebotaru V,Chiaravalli M,Boletta A,Piontek K,Germino GG,Weinman EJ,Watnick T,Qian F
Tue Nov 18 00:00:00 EST 2014
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.
Nature communications
Kim H,Xu H,Yao Q,Li W,Huang Q,Outeda P,Cebotaru V,Chiaravalli M,Boletta A,Piontek K,Germino GG,Weinman EJ,Watnick T,Qian F
Tue Nov 18 00:00:00 EST 2014
Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms.
PloS one
Lee JY,Hong WJ,Majeti R,Stearns T
Tue Nov 18 00:00:00 EST 2014
Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms.
PloS one
Lee JY,Hong WJ,Majeti R,Stearns T
Tue Nov 18 00:00:00 EST 2014
Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division.
eLife
Mora-Bermúdez F,Matsuzaki F,Huttner WB
Fri Jul 04 00:00:00 EDT 2014
Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division.
eLife
Mora-Bermúdez F,Matsuzaki F,Huttner WB
Fri Jul 04 00:00:00 EDT 2014
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Cell
Mukhopadhyay S,Wen X,Ratti N,Loktev A,Rangell L,Scales SJ,Jackson PK
Thu Jan 17 00:00:00 EST 2013
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Cell
Mukhopadhyay S,Wen X,Ratti N,Loktev A,Rangell L,Scales SJ,Jackson PK
Thu Jan 17 00:00:00 EST 2013
Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.
Cell
Paridaen JT,Wilsch-Bräuninger M,Huttner WB
Thu Oct 10 00:00:00 EDT 2013
Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.
Cell
Paridaen JT,Wilsch-Bräuninger M,Huttner WB
Thu Oct 10 00:00:00 EDT 2013
Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.
Cell
Paridaen JT,Wilsch-Bräuninger M,Huttner WB
Thu Oct 10 00:00:00 EDT 2013
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.
Science (New York, N.Y.)
Bhogaraju S,Cajanek L,Fort C,Blisnick T,Weber K,Taschner M,Mizuno N,Lamla S,Bastin P,Nigg EA,Lorentzen E
Fri Aug 30 00:00:00 EDT 2013
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.
Science (New York, N.Y.)
Bhogaraju S,Cajanek L,Fort C,Blisnick T,Weber K,Taschner M,Mizuno N,Lamla S,Bastin P,Nigg EA,Lorentzen E
Fri Aug 30 00:00:00 EDT 2013
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia.
Nature methods
Su S,Phua SC,DeRose R,Chiba S,Narita K,Kalugin PN,Katada T,Kontani K,Takeda S,Inoue T
Fri Nov 01 00:00:00 EDT 2013
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia.
Nature methods
Su S,Phua SC,DeRose R,Chiba S,Narita K,Kalugin PN,Katada T,Kontani K,Takeda S,Inoue T
Fri Nov 01 00:00:00 EDT 2013
Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration.
The Journal of clinical investigation
Drivas TG,Holzbaur EL,Bennett J
Tue Oct 01 00:00:00 EDT 2013
Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration.
The Journal of clinical investigation
Drivas TG,Holzbaur EL,Bennett J
Tue Oct 01 00:00:00 EDT 2013
CCDC41 is required for ciliary vesicle docking to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Joo K,Kim CG,Lee MS,Moon HY,Lee SH,Kim MJ,Kweon HS,Park WY,Kim CH,Gleeson JG,Kim J
Tue Apr 09 00:00:00 EDT 2013
CCDC41 is required for ciliary vesicle docking to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Joo K,Kim CG,Lee MS,Moon HY,Lee SH,Kim MJ,Kweon HS,Park WY,Kim CH,Gleeson JG,Kim J
Tue Apr 09 00:00:00 EDT 2013
Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.
American journal of human genetics
Davidson AE,Schwarz N,Zelinger L,Stern-Schneider G,Shoemark A,Spitzbarth B,Gross M,Laxer U,Sosna J,Sergouniotis PI,Waseem NH,Wilson R,Kahn RA,Plagnol V,Wolfrum U,Banin E,Hardcastle AJ,Cheetham ME,Sharon D,Webster AR
Thu Aug 08 00:00:00 EDT 2013
Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.
American journal of human genetics
Davidson AE,Schwarz N,Zelinger L,Stern-Schneider G,Shoemark A,Spitzbarth B,Gross M,Laxer U,Sosna J,Sergouniotis PI,Waseem NH,Wilson R,Kahn RA,Plagnol V,Wolfrum U,Banin E,Hardcastle AJ,Cheetham ME,Sharon D,Webster AR
Thu Aug 08 00:00:00 EDT 2013
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans.
American journal of human genetics
Halbritter J,Bizet AA,Schmidts M,Porath JD,Braun DA,Gee HY,McInerney-Leo AM,Krug P,Filhol E,Davis EE,Airik R,Czarnecki PG,Lehman AM,Trnka P,Nitschké P,Bole-Feysot C,Schueler M,Knebelmann B,Burtey S,Szabó AJ,Tory K,Leo PJ,Gardiner B,McKenzie FA,Zankl A,Brown MA,Hartley JL,Maher ER,Li C,Leroux MR,Scambler PJ,Zhan SH,Jones SJ,Kayserili H,Tuysuz B,Moorani KN,Constantinescu A,Krantz ID,Kaplan BS,Shah JV,Hurd TW,Doherty D,Katsanis N,Duncan EL,Otto EA,Beales PL,Mitchison HM,Saunier S,Hildebrandt F
Thu Nov 07 00:00:00 EST 2013
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans.
American journal of human genetics
Halbritter J,Bizet AA,Schmidts M,Porath JD,Braun DA,Gee HY,McInerney-Leo AM,Krug P,Filhol E,Davis EE,Airik R,Czarnecki PG,Lehman AM,Trnka P,Nitschké P,Bole-Feysot C,Schueler M,Knebelmann B,Burtey S,Szabó AJ,Tory K,Leo PJ,Gardiner B,McKenzie FA,Zankl A,Brown MA,Hartley JL,Maher ER,Li C,Leroux MR,Scambler PJ,Zhan SH,Jones SJ,Kayserili H,Tuysuz B,Moorani KN,Constantinescu A,Krantz ID,Kaplan BS,Shah JV,Hurd TW,Doherty D,Katsanis N,Duncan EL,Otto EA,Beales PL,Mitchison HM,Saunier S,Hildebrandt F
Thu Nov 07 00:00:00 EST 2013
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.
The Journal of cell biology
Kuhns S,Schmidt KN,Reymann J,Gilbert DF,Neuner A,Hub B,Carvalho R,Wiedemann P,Zentgraf H,Erfle H,Klingmüller U,Boutros M,Pereira G
Mon Feb 18 00:00:00 EST 2013
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.
The Journal of cell biology
Kuhns S,Schmidt KN,Reymann J,Gilbert DF,Neuner A,Hub B,Carvalho R,Wiedemann P,Zentgraf H,Erfle H,Klingmüller U,Boutros M,Pereira G
Mon Feb 18 00:00:00 EST 2013
VDAC3 and Mps1 negatively regulate ciliogenesis.
Cell cycle (Georgetown, Tex.)
Majumder S,Fisk HA
Fri Mar 01 00:00:00 EST 2013
VDAC3 and Mps1 negatively regulate ciliogenesis.
Cell cycle (Georgetown, Tex.)
Majumder S,Fisk HA
Fri Mar 01 00:00:00 EST 2013
Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis.
Human molecular genetics
Liu C,Lin C,Whitaker DT,Bakeri H,Bulgakov OV,Liu P,Lei J,Dong L,Li T,Swaroop A
Sat Jun 01 00:00:00 EDT 2013
Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis.
Human molecular genetics
Liu C,Lin C,Whitaker DT,Bakeri H,Bulgakov OV,Liu P,Lei J,Dong L,Li T,Swaroop A
Sat Jun 01 00:00:00 EDT 2013
The ciliary protein Ftm is required for ventricular wall and septal development.
PloS one
Gerhardt C,Lier JM,Kuschel S,Rüther U
Tue Sep 10 00:00:00 EDT 2013
The ciliary protein Ftm is required for ventricular wall and septal development.
PloS one
Gerhardt C,Lier JM,Kuschel S,Rüther U
Tue Sep 10 00:00:00 EDT 2013
Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys.
American journal of physiology. Renal physiology
Kim JI,Kim J,Jang HS,Noh MR,Lipschutz JH,Park KM
Wed May 15 00:00:00 EDT 2013
Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys.
American journal of physiology. Renal physiology
Kim JI,Kim J,Jang HS,Noh MR,Lipschutz JH,Park KM
Wed May 15 00:00:00 EDT 2013
Visualizing renal primary cilia.
Nephrology (Carlton, Vic.)
Deane JA,Verghese E,Martelotto LG,Cain JE,Galtseva A,Rosenblum ND,Watkins DN,Ricardo SD
Fri Mar 01 00:00:00 EST 2013
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Proceedings of the National Academy of Sciences of the United States of America
Humbert MC,Weihbrecht K,Searby CC,Li Y,Pope RM,Sheffield VC,Seo S
Tue Nov 27 00:00:00 EST 2012
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Proceedings of the National Academy of Sciences of the United States of America
Humbert MC,Weihbrecht K,Searby CC,Li Y,Pope RM,Sheffield VC,Seo S
Tue Nov 27 00:00:00 EST 2012
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Proceedings of the National Academy of Sciences of the United States of America
Humbert MC,Weihbrecht K,Searby CC,Li Y,Pope RM,Sheffield VC,Seo S
Tue Nov 27 00:00:00 EST 2012
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Proceedings of the National Academy of Sciences of the United States of America
Humbert MC,Weihbrecht K,Searby CC,Li Y,Pope RM,Sheffield VC,Seo S
Tue Nov 27 00:00:00 EST 2012
SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors.
The Journal of cell biology
Li Y,Zhang Q,Wei Q,Zhang Y,Ling K,Hu J
Mon Nov 12 00:00:00 EST 2012
SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors.
The Journal of cell biology
Li Y,Zhang Q,Wei Q,Zhang Y,Ling K,Hu J
Mon Nov 12 00:00:00 EST 2012
SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors.
The Journal of cell biology
Li Y,Zhang Q,Wei Q,Zhang Y,Ling K,Hu J
Mon Nov 12 00:00:00 EST 2012
SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors.
The Journal of cell biology
Li Y,Zhang Q,Wei Q,Zhang Y,Ling K,Hu J
Mon Nov 12 00:00:00 EST 2012
Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination.
Development (Cambridge, England)
Wilsch-Bräuninger M,Peters J,Paridaen JT,Huttner WB
Sun Jan 01 00:00:00 EST 2012
Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination.
Development (Cambridge, England)
Wilsch-Bräuninger M,Peters J,Paridaen JT,Huttner WB
Sun Jan 01 00:00:00 EST 2012
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Nature cell biology
Chih B,Liu P,Chinn Y,Chalouni C,Komuves LG,Hass PE,Sandoval W,Peterson AS
Sun Dec 18 00:00:00 EST 2011
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Nature cell biology
Chih B,Liu P,Chinn Y,Chalouni C,Komuves LG,Hass PE,Sandoval W,Peterson AS
Sun Dec 18 00:00:00 EST 2011
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
PLoS genetics
Seo S,Zhang Q,Bugge K,Breslow DK,Searby CC,Nachury MV,Sheffield VC
Tue Nov 01 00:00:00 EDT 2011
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.
PLoS genetics
Seo S,Zhang Q,Bugge K,Breslow DK,Searby CC,Nachury MV,Sheffield VC
Tue Nov 01 00:00:00 EDT 2011
