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Recommended positive controls: 293T, mouse Liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.
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Protein Aliases: ADP-ribosylation factor like GTPase 13B; ADP-ribosylation factor-like 13B; ADP-ribosylation factor-like 2-like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein hennin
Gene Aliases: A530097K21Rik; A930014M17Rik; ARL13B; ARL2L1; C530009C10Rik; hnn; JBTS8
UniProt ID: (Human) Q3SXY8, (Mouse) Q640N2
Entrez Gene ID: (Human) 200894, (Mouse) 68146
Molecular Function:
G-protein
enzyme modulator
small GTPase
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