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Invitrogen
ARL2BP Polyclonal Antibody
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Product Details
PA5-49972
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from internal of human ARL2BP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total ARL2BP protein
Target Information
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2. GTP with high affinity but does not interact with ARL2. GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2. GTP but lack of ARL2 GTPase-activating protein activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP ribosylation factor like GTPase 2 binding protein; ADP-ribosylation factor like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ADP-ribosylation-like 2 binding protein; Arf-like 2 binding protein BART1; ARF-like 2-binding protein; Arl2 binding protein; ARL2-binding protein; Binder of ARF2 protein 1; binder of Arl Two; binder of Arl2; retinitis pigmentosa 66 (autosomal recessive); unnamed protein product
Gene Aliases: 1700010P10Rik; 1700027H16Rik; 6330544B05Rik; AI482273; AI849834; ARL2BP; BART; BART1; RP66; RP82
UniProt ID: (Human) Q9Y2Y0, (Rat) Q4V8C5, (Mouse) Q9D385
Entrez Gene ID: (Human) 23568, (Rat) 498910, (Mouse) 107566
positive regulation of tyrosine phosphorylation of Stat3 protein
maintenance of protein location in nucleus
regulation of nucleic acid-templated transcription
signal transduction
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of transcription, DNA-templated
regulation of catalytic activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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