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Proteintech
ARNTL Polyclonal Antibody
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Product Details
14268-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARNTL Fusion Protein Ag5586 (1-303 aa encoded by BC041129)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MADQRMDIS STISDFMSPG PTDLLSSSLG TSGVDCNRKR KGSSTDYQES MDTDKDDPHG RLEYTEHQGR IKNAREAHSQ IEKRRRDKMN SFIDELASLV PTCNAMSRKL DKLTVLRMAV QHMKTLRGAT NPYTEANYKP TFLSDDELKH LILRAADGFL FVVGCDRGKI LFVSESVFKI LNYSQNDLIG QSLFDYLHPK DIAKVKEQLS SSDTAPRERL IDAKTGLPVK TDITPGPSRL CSGARRSFFC RMKCNRPSVK VEDKDFPSTC SKKKDRKSFC TIHSTGYLKS WPPTKMGLDE DNEP (1-303 aa encoded by BC041129)
Target Information
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ARNT-like protein 1, brain and muscle; Arnt3; aryl hydrocarbon receptor nuclear translocator like; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic helix-loop-helix ARNT-like protein 1; basic helix-loop-helix family member e5; basic-helix-loop-helix-PAS orphan MOP3; Basic-helix-loop-helix-PAS protein MOP3; bHLH-PAS protein JAP3; bHLHe5; Brain and muscle ARNT-like 1; CG8727 PA; Class E basic helix-loop-helix protein 5; cycle; Member of PAS protein 3; member of PAS superfamily 3; MGC47515; mutant basic helix-loop-helix ARNT-like protein 1; PAS domain containing 3; PAS domain-containing protein 3; testis tissue sperm-binding protein Li 50e; Tic; unnamed protein product
Gene Aliases: Arnt3; ARNTL; ARNTL1; BHLHE5; BMAL1; BMAL1b; bmal1b'; BMAL1c; JAP3; MOP3; PASD3; TIC
UniProt ID: (Rat) Q9EPW1, (Mouse) Q9WTL8, (Human) O00327
Entrez Gene ID: (Rat) 29657, (Mouse) 11865, (Human) 406
transcription regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
aryl hydrocarbon receptor binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity
Hsp90 protein binding
E-box binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
transcription factor binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
DNA-binding transcription factor binding
sequence-specific double-stranded DNA binding
basic helix-loop-helix transcription factor
protein import into nucleus, translocation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
signal transduction
spermatogenesis
circadian rhythm
negative regulation of TOR signaling
circadian regulation of gene expression
regulation of protein catabolic process
regulation of hair cycle
regulation of circadian rhythm
positive regulation of circadian rhythm
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of neurogenesis
regulation of insulin secretion
regulation of cell cycle
response to redox state
positive regulation of canonical Wnt signaling pathway
oxidative stress-induced premature senescence
regulation of type B pancreatic cell development
negative regulation of glucocorticoid receptor signaling pathway
regulation of cellular senescence
positive regulation of skeletal muscle cell differentiation
rhythmic process
regulation of transcription from RNA polymerase II promoter
energy homeostasis
negative regulation of cold-induced thermogenesis
positive regulation of protein acetylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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