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Proteintech
ARP3 Polyclonal Antibody
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Product Details
13822-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARP3/ARP3B Fusion Protein Ag4922 (156-418 aa encoded by BC044590)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes endogenous ARP3 and may cross-react with ATCR3B.
Immunogen sequence: RQVGERTLT GTVIDSGDGV THVIPVAEGY VIGSCIKHIP IAGRDITYFI QQLLRDREVG IPPEQSLETA KAVKERYSYV CPDLVKEFNK YDTDGSKWIK QYTGINAISK KEFSIDVGYE RFLGPEIFFH PEFANPDFTQ PISEVVDEVI QNCPIDVRRP LYKNIVLSGG STMFRDFGRR LQRDLKRTVD ARLKLSEELS GGRLKPKPID VQVITHHMQR YAVWFGGSML ASTPEFYQVC HTKKDYEEIG PSICRHNPVF GVMS (156-418 aa encoded by B C044590)
Target Information
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Actin-like protein 3; Actin-related protein 3; actin-related protein 3 homolog (yest); ARP3 actin related protein 3 homolog; ARP3 actin-related protein 3 homolog; one of seven subunits of the Arp2/3 protein complex; unnamed protein product
Gene Aliases: 1200003A09Rik; ACTR3; ARP3
UniProt ID: (Human) P61158, (Rat) Q4V7C7, (Mouse) Q99JY9
Entrez Gene ID: (Human) 10096, (Rat) 81732, (Mouse) 74117
establishment or maintenance of cell polarity
asymmetric cell division
positive regulation of lamellipodium assembly
meiotic chromosome movement towards spindle pole
cell projection organization
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
positive regulation of transcription from RNA polymerase II promoter
meiotic cell cycle
spindle localization
cilium morphogenesis
actin polymerization-dependent cell motility
cellular response to interferon-gamma
response to carbohydrate
positive regulation of actin filament polymerization
regulation of myosin II filament organization
positive regulation of neuron differentiation
response to antibiotic
positive regulation of dendrite morphogenesis
positive regulation of filopodium assembly
actin filament organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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