Proteintech

ARP3 Polyclonal Antibody

FIGURE: 1 / 4

ARP3 Antibody (13822-1-AP) in WB

Mouse spleen tissue were subjected to SDS PAGE followed by western blot with 13822-1-AP (ARP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

ARP3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13822-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 8 publications 8 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 4 publications 4 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ARP3/ARP3B Fusion Protein Ag4922 (156-418 aa encoded by BC044590)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.24 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody recognizes endogenous ARP3 and may cross-react with ATCR3B.^M
^M
Immunogen sequence: RQVGERTLT GTVIDSGDGV THVIPVAEGY VIGSCIKHIP IAGRDITYFI QQLLRDREVG IPPEQSLETA KAVKERYSYV CPDLVKEFNK YDTDGSKWIK QYTGINAISK KEFSIDVGYE RFLGPEIFFH PEFANPDFTQ PISEVVDEVI QNCPIDVRRP LYKNIVLSGG STMFRDFGRR LQRDLKRTVD ARLKLSEELS GGRLKPKPID VQVITHHMQR YAVWFGGSML ASTPEFYQVC HTKKDYEEIG PSICRHNPVF GVMS (156-418 aa encoded by B C044590)

Target Information

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.

eLife

Zhang C,Schekman R

Fri Mar 10 00:00:00 UTC 2023

Actin cables and comet tails organize mitochondrial networks in mitosis.

Nature

Moore AS,Coscia SM,Simpson CL,Ortega FE,Wait EC,Heddleston JM,Nirschl JJ,Obara CJ,Guedes-Dias P,Boecker CA,Chew TL,Theriot JA,Lippincott-Schwartz J,Holzbaur ELF

Mon Mar 01 00:00:00 UTC 2021

Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.

ACS nano

Kang Y,Liu J,Yin S,Jiang Y,Feng X,Wu J,Zhang Y,Chen A,Zhang Y,Shao L

Tue Mar 24 00:00:00 UTC 2020

Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.

ACS nano

Kang Y,Liu J,Yin S,Jiang Y,Feng X,Wu J,Zhang Y,Chen A,Zhang Y,Shao L

Tue Mar 24 00:00:00 UTC 2020

WDR63 inhibits Arp2/3-dependent actin polymerization and mediates the function of p53 in suppressing metastasis.

EMBO reports

Zhao K,Wang D,Zhao X,Wang C,Gao Y,Liu K,Wang F,Wu X,Wang X,Sun L,Zang J,Mei Y

Fri Apr 03 00:00:00 UTC 2020

Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma.

International journal of biological sciences

Dong X,Feng M,Yang H,Liu H,Guo H,Gao X,Liu Y,Liu R,Zhang N,Chen R,Kong R

Mon Apr 04 00:00:00 UTC 2022

The Legionella pneumophila effector WipA disrupts host F-actin polymerisation by hijacking phosphotyrosine signalling.

Cellular microbiology

He L,Lin Y,Ge ZH,He SY,Zhao BB,Shen D,He JG,Lu YJ

Sat Jun 01 00:00:00 UTC 2019

Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.

Chemosphere

He X,Sun Z,Manthari RK,Wu P,Wang J

Thu Nov 01 00:00:00 UTC 2018

Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.

Chemosphere

He X,Sun Z,Manthari RK,Wu P,Wang J

Thu Nov 01 00:00:00 UTC 2018

Regulation of MRTF-A by JMY via a nucleation-independent mechanism.

Cell communication and signaling : CCS

Kluge F,Weissbach J,Weber A,Stradal T,Posern G

Wed Nov 21 00:00:00 UTC 2018

Molecular and cellular biology

Weissbach J,Schikora F,Weber A,Kessels M,Posern G

Sun May 15 00:00:00 UTC 2016

Molecular and cellular biology

Weissbach J,Schikora F,Weber A,Kessels M,Posern G

Sun May 15 00:00:00 UTC 2016

Molecular and cellular biology

Weissbach J,Schikora F,Weber A,Kessels M,Posern G

Sun May 15 00:00:00 UTC 2016

Molecular and cellular biology

Weissbach J,Schikora F,Weber A,Kessels M,Posern G

Sun May 15 00:00:00 UTC 2016

Decreased expression of cortactin in the schizophrenia brain.

Neuroreport

Bhambhvani HP,Simmons M,Haroutunian V,Meador-Woodruff JH

Wed Feb 10 00:00:00 UTC 2016

N-wasp is required for structural integrity of the blood-testis barrier.

PLoS genetics

Xiao X,Mruk DD,Tang EI,Massarwa R,Mok KW,Li N,Wong CK,Lee WM,Snapper SB,Shilo BZ,Schejter ED,Cheng CY

Sun Jun 01 00:00:00 UTC 2014

N-wasp is required for structural integrity of the blood-testis barrier.

PLoS genetics

Xiao X,Mruk DD,Tang EI,Massarwa R,Mok KW,Li N,Wong CK,Lee WM,Snapper SB,Shilo BZ,Schejter ED,Cheng CY

Sun Jun 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: Actin-like protein 3; Actin-related protein 3; actin-related protein 3 homolog (yest); ARP3 actin-related protein 3 homolog

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Gene Aliases: 1200003A09Rik; ACTR3; ARP3

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UniProt ID: (Human) P61158, (Rat) Q4V7C7, (Mouse) Q99JY9

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Entrez Gene ID: (Human) 10096, (Rat) 81732, (Mouse) 74117

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Function(s)

structural constituent of cytoskeleton protein binding ATP binding actin filament binding nucleotide binding actin binding actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein

Process(es)

movement of cell or subcellular component establishment or maintenance of cell polarity asymmetric cell division meiotic chromosome movement towards spindle pole meiotic cytokinesis Arp2/3 complex-mediated actin nucleation Fc-gamma receptor signaling pathway involved in phagocytosis ephrin receptor signaling pathway spindle localization cilium morphogenesis response to carbohydrate positive regulation of lamellipodium assembly positive regulation of actin filament polymerization regulation of myosin II filament organization positive regulation of neuron differentiation response to antibiotic positive regulation of dendrite morphogenesis meiotic cell cycle positive regulation of filopodium assembly actin filament organization cell projection organization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ARP3 Polyclonal Antibody

ARP3 Antibody (13822-1-AP) in WB

Product Details

13822-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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