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ARP4 Polyclonal Antibody
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Product Details
BS-5919R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ANGPTL4/ARP4, amino acids 331-406.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 425O18-1; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; contains fibrinogen-like domain; Fasting-i; Fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; Secreted protein Bk89; unnamed protein product
Gene Aliases: ANGPTL4; ARP4; Bk89; Farp; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; PP1158; PSEC0166; TGQTL; UNQ171; UNQ171/PRO197
UniProt ID: (Human) Q9BY76, (Mouse) Q9Z1P8, (Rat) Q6TMA8
Entrez Gene ID: (Human) 51129, (Mouse) 57875, (Rat) 362850
angiogenesis
response to hypoxia
lipid metabolic process
blood coagulation
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of apoptotic process
protein unfolding
negative regulation of fatty acid biosynthetic process
positive regulation of angiogenesis
positive regulation of multicellular organismal process
triglyceride homeostasis
endothelial cell apoptotic process
regulation of chylomicron remodeling
negative regulation of endothelial cell apoptotic process
cellular response to starvation
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
protein homooligomerization
regulation of lipid metabolic process
cell differentiation
negative regulation of catalytic activity
protein oligomerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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