|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 307 of ARPC1A (Uniprot ID#Q92747)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34870 targets ARPC1A in WB applications and shows reactivity with Human samples.
The PA5-34870 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 307 of ARPC1A (Uniprot ID#Q92747).
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin binding protein (Schizosaccharomyces pombe sop2-like); actin related protein 2/3 complex subunit 1A, 41kDa; actin related protein 2/3 complex, subunit 1A, 41kDa; Actin-related protein 2/3 complex subunit 1A; Arc40; epididymis luminal protein 68; epididymis secretory protein Li 307; SOP2-like protein; SOP2Hs; SOP2L
Gene Aliases: Arc40; ARPC1A; HEL-68; HEL-S-307; SOP2Hs; SOP2L
UniProt ID: (Human) B4DLQ7
Entrez Gene ID: (Human) 10552
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