Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: AYIKEVDEKP ASTPWGSKMP FGQLMSEFGG SGTGGWVHGV SFSASGSRLA WVSHDSTVSV ADASKSVQVS TLKTEFLPLL SVSFVSENSV VAAGHDCCPM LFNYDDRGCL TFVSKLDIPK QSIQRNMSAM ERFRNMDKRA TTEDRNTALE TLHQNSITQV SIYEVDKQDC RKFCTTGIDG; Positive Samples: U-251MG; Cellular Location: Cytoplasm, cytoskeleton
ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
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Protein Aliases: actin binding protein (Schizosaccharomyces pombe sop2-like); actin related protein 2/3 complex subunit 1A, 41kDa; actin related protein 2/3 complex, subunit 1A, 41kDa; Actin-related protein 2/3 complex subunit 1A; ARC1A; epididymis luminal protein 68; epididymis secretory protein Li 307; Sid 329; SOP2-like protein
Gene Aliases: 0610010H08Rik; 1110030K07Rik; 41kDa; AA407347; Arc40; ARPC1A; HEL-68; HEL-S-307; Sid32; Sid329; SOP2Hs; SOP2L
UniProt ID: (Human) Q92747, (Mouse) Q9R0Q6
Entrez Gene ID: (Human) 10552, (Mouse) 56443
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