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Proteintech
ARPC2 Polyclonal Antibody
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Product Details
15058-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARPC2 Fusion Protein Ag7041 (1-300 aa encoded by BC000590)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MILLEVNNR IIEETLALKF ENAAAGNKPE AVEVTFADFD GVLYHISNPN GDKTKVMVSI SLKFYKELQA HGADELLKRV YGSFLVNPES GYNVSLLYDL ENLPASKDSI VHQAGMLKRN CFASVFEKYF QFQEEGKEGE NRAVIHYRDD ETMYVESKKD RVTVVFSTVF KDDDDVVIGK VFMQEFKEGR RASHTAPQVL FSHREPPLEL KDTDAAVGDN IGYITFVLFP RHTNASARDN TINLIHTFRD YLHYHIKCSK AYIHTRMRAK TSDFLKVLNR ARPDAEKKEM KTITGKTFSS R (1-300 aa encoded by BC000590)
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin related protein 2/3 complex subunit 2, 34kDa; actin related protein 2/3 complex, subunit 2, 34kDa; Actin-related protein 2/3 complex subunit 2; actin-related protein 2/3 complex subunit 2 {ECO:0000250|UniProtKB:O15144}; Arp2/3 complex 34 kDa subunit; arp2/3 complex 34 kDa subunit {ECO:0000250|UniProtKB:O15144}; ARP2/3 protein complex subunit 34; arpc2 {ECO:0000250|UniProtKB:O15144}; p34-ARC; p34-ARC {ECO:0000250|UniProtKB:O15144}; testis tissue sperm-binding protein Li 53e
Gene Aliases: 2210023N03Rik; 34kDa; ARC34; ARPC2; p34-Arc; PNAS-139; PRO2446
UniProt ID: (Human) O15144, (Mouse) Q9CVB6
Entrez Gene ID: (Human) 10109, (Rat) 301511, (Mouse) 76709
positive regulation of lamellipodium assembly
positive regulation of actin filament polymerization
Arp2/3 complex-mediated actin nucleation
positive regulation of substrate adhesion-dependent cell spreading
movement of cell or subcellular component
Fc-gamma receptor signaling pathway involved in phagocytosis
ephrin receptor signaling pathway
regulation of actin filament polymerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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