The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy , a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
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Protein Aliases: ARSA; Arylsulfatase A; Arylsulfatase A component B; Arylsulfatase A component C; ASA; Cerebroside sulfatase; Cerebroside-sulfatase; MLD
Gene Aliases: ARSA; As-2; AS-A; As2; ASA; AW212749; MLD; TISP73
Molecular Function: hydrolase