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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LVFLLADDL GWNDVGFHGS RIRTPHLDAL AAGGVLLDNY YTQPLCTPSR SQLLTGRYQI RTGLQHQIIW PCQPSCVPLD EKLLPQLLKE AGYTTHMVGK WHLGMYRKEC LPTRRGFDTY FGYLLGSEDY YSHERCTLID ALNVTRCALD FRDGEEVATG YKNMYSTNIF TKRAIALITN HPPEKPLFLY LALQSVHEPL QVPEEYLKPY DFIQDKNRHH YAGMVSLMDE AVGNVTAALK SSGLWNNTVF IFSTDNGGQT LAGGNNWPLR GRKWSLWEGG VRGVGFVASP LLKQKGVKNR ELIHISDWLP TLVKLARGHT NGTKPLDGFD VWKTISEGSP SPRIELLHNI DPNFVDSSPY WPECSLLL (47-413 aa encoded by BC029051 )
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B precursor; arylsulfatase B precursor (EC 3.1.6.1); arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; ASB; G4S; N-acetylgalactosamine-4-sulfatase; unnamed protein product
Gene Aliases: 1110007C02Rik; As-1; As-1r; As-1s; As-1t; As1; As1-r; As1-s; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6
UniProt ID: (Human) P15848, (Mouse) P50429, (Rat) P50430
Entrez Gene ID: (Human) 411, (Mouse) 11881, (Rat) 25227
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