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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide corresponding to amino acids 40-51 (IVKGNRKEAARIYGANLKRRNAQGKSAL) and 250-265 (YGANLKRRNAQGKSAL) of Human ASB11.|
|Storage buffer||PBS with 0.1mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29820 detects ASB11 from human samples.
PA1-29820 has been successfully used in Western blot applications.
The PA1-29820 immunogen is: Synthetic peptide: corresponding to amino acids 40-51 (IVKGNRKEAARIYGANLKRRNAQGKSAL) and 250-265 (YGANLKRRNAQGKSAL) of Human ASB11.
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase; ankyrin repeat domain-containing SOCS box protein ASB11; ASB-11; DKFZp779E2460; MGC119168; MGC119169