|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides corresponding to residues 63-75 and 166-180 of human Asb-3.|
|Storage buffer||whole serum diluted in PBS with 100µg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody will not cross-react with mouse or rat asb-3.
Suggested positive control: human spleen protein, antigen standard for ASB3 (transient overexpression lysate), human spleen.
The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain “SOCS boxes” but differ from other families of protein in the motifs they contain upstream of the SOCS box(1). SOCS boxes are carboxy-terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.