Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: NT2D1, U87-MG.
Predicted reactivity: Mouse (100%), Rat (98%), Zebrafish (93%), Xenopus laevis (96%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ankyrin repeat and SOCS box protein 7; ankyrin repeat and SOCS box-containing 7; ASB-7
Gene Aliases: ASB7
UniProt ID: (Human) Q9H672
Entrez Gene ID: (Human) 140460
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