|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 312 of Human ASC1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31536 targets ASC1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31536 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 312 of Human ASC1.
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activating signal cointegrator 1; ASC-1; ASC1; HsT17391; thyroid receptor interacting protein 4; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; zinc finger, C2HC5-type
Gene Aliases: ASC-1; ASC1; HsT17391; SMABF1; TRIP4; ZC2HC5
UniProt ID: (Human) Q15650
Entrez Gene ID: (Human) 9325
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