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Bethyl Laboratories
ASCC3 Polyclonal Antibody
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FIGURE: 1 / 2
ASCC3 Antibody (A304-014A) in WB
Detection of human and mouse ASCC3 by western blot. Samples: Whole cell lysate (50 µg) from HEK293T, HeLa, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-ASCC3 antibody (Product # A304-014A) (lot A304-014A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A304-014A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 175 to 225 of human Activating Signal Cointegrator 1 Complex Subunit 3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating signal cointegrator 1 complex subunit 3; ASC-1 complex subunit P200; ASC1p200; dJ121G13.4; dJ467N11.1; Helicase, ATP binding 1; RNA helicase family; Trip4 complex subunit p200; unnamed protein product
Gene Aliases: ASC1p200; ASCC3; B630009I04Rik; BC023451; D430001L07Rik; D630041L21; HELIC1; MRT81; RNAH; RQT2
UniProt ID: (Human) Q8N3C0, (Mouse) E9PZJ8
Entrez Gene ID: (Human) 10973, (Mouse) 77987
DNA replication
DNA repair
DNA dealkylation involved in DNA repair
protein monoubiquitination
cellular response to DNA damage stimulus
ribosome disassembly
protein ufmylation
rescue of stalled ribosome
CAT tailing
ribosome-associated ubiquitin-dependent protein catabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell proliferation
DNA duplex unwinding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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