Immunogen sequence: GREAIESGAA FLFMTFHLKD SVGHKETKAI KQMFGPFPSS SATAACNATN RIISHFSQDD LTALVQMTEK EHGDRVFFGK NLAFSFDMHD LDHFDELPIN G
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activating signal cointegrator 1 complex subunit 3; ASC-1 complex subunit P200; ASC1p200; dJ121G13.4; dJ467N11.1; Helicase, ATP binding 1; RNA helicase family; Trip4 complex subunit p200
Gene Aliases: ASC1p200; ASCC3; HELIC1; RNAH
UniProt ID: (Human) Q8N3C0
Entrez Gene ID: (Human) 10973
Molecular Function: scaffold/adaptor protein