Search
Bethyl Laboratories
ASH1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
A301-749A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 2919 and 2969 of human absent, small and homeotic disks protein 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
ASH1 (ASH1L) is a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. Diseases associated with ASH1 include Mental Retardation, Autosomal Dominant 52 and Pulpitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Absent small and homeotic disks protein 1 homolog; absent, small, or homeotic discs 1; ash1 (absent, small, or homeotic)-like; ASH1-like protein; chromatin remodeling factor; Histone-lysine N-methyltransferase ASH1L; huASH1; Lysine N-methyltransferase 2H; probable histone-lysine N-methyltransferase ASH1L; unnamed protein product
Gene Aliases: 8030453L17Rik; ASH1; ASH1L; ASH1L1; E430018P19Rik; KIAA1420; KMT2H; MRD52
UniProt ID: (Human) Q9NR48, (Mouse) Q99MY8
Entrez Gene ID: (Human) 55870, (Mouse) 192195
DNA binding
chromatin binding
methyltransferase activity
zinc ion binding
transferase activity
histone methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
metal ion binding
histone methyltransferase activity (H3-K9 specific)
histone methyltransferase activity (H3-K36 specific)
histone H3 methyltransferase activity
histone H3K9me2 methyltransferase activity
histone H3K9 monomethyltransferase activity
histone H3K36 trimethyltransferase activity
histone-lysine N-methyltransferase activity
chromatin/chromatin-binding, or -regulatory protein
histone modifying enzyme
MAPK cascade
skeletal system development
negative regulation of acute inflammatory response
chromatin organization
chromatin remodeling
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
inflammatory response
single fertilization
post-embryonic development
regulation of gene expression
sperm motility
methylation
negative regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
decidualization
sebaceous gland development
negative regulation of inflammatory response
uterus morphogenesis
tarsal gland development
uterine gland development
transcription, DNA-templated
chromatin modification
interleukin-6 production
negative regulation of I-kappaB kinase/NF-kappaB signaling
histone H3-K4 methylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support