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Invitrogen
ASH1 Polyclonal Antibody
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Product Details
PA5-144261
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Histone-lysine N-methyltransferase ASH1L protein (1906-2160AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
ASH1 (ASH1L) is a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. Diseases associated with ASH1 include Mental Retardation, Autosomal Dominant 52 and Pulpitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Absent small and homeotic disks protein 1 homolog; ash1 (absent, small, or homeotic)-like; ASH1-like protein; Histone-lysine N-methyltransferase ASH1L; huASH1; Lysine N-methyltransferase 2H; probable histone-lysine N-methyltransferase ASH1L
Gene Aliases: ASH1; ASH1L; ASH1L1; KIAA1420; KMT2H
UniProt ID: (Human) Q9NR48
Entrez Gene ID: (Human) 55870
negative regulation of acute inflammatory response
DNA packaging
transcription from RNA polymerase II promoter
cell-cell signaling
interleukin-6 production
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
histone H3-K4 methylation
histone H3-K36 dimethylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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