Peptide sequence: VRASAHGTEL LLDICVSLKL LKVETRGGKA FYRNTELSSD YLTTVSPTSQ
Sequence homology: Dog: 83%; Horse: 92%; Human: 100%
ASMT belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland.
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Protein Aliases: acetylserotonin methyltransferase (Y chromosome); acetylserotonin N-methyltransferase; Acetylserotonin O-methyltransferase; HIOMT; Hydroxyindole O-methyltransferase
Gene Aliases: ASMT; ASMTY; HIOMT; HIOMTY
UniProt ID: (Human) P46597