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Invitrogen
ASS1 Polyclonal Antibody
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Product Details
PA5-117797
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human ASS1 fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Argininosuccinate synthase; argininosuccinate synthetase; argininosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; epididymis secretory sperm binding protein; RP11-618A20.2; unnamed protein product
Gene Aliases: ASS; ASS1; CTLN1
UniProt ID: (Human) P00966
Entrez Gene ID: (Human) 445
urea cycle
citrulline metabolic process
argininosuccinate metabolic process
kidney development
liver development
arginine biosynthetic process
aspartate metabolic process
acute-phase response
midgut development
response to nutrient
circadian rhythm
cellular amino acid biosynthetic process
response to xenobiotic stimulus
response to toxic substance
response to zinc ion
response to mycotoxin
response to amine
response to estradiol
response to lipopolysaccharide
response to amino acid
response to peptide hormone
positive regulation of nitric oxide biosynthetic process
response to steroid hormone
response to glucocorticoid
response to growth hormone
diaphragm development
response to fatty acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to ammonium ion
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to glucagon stimulus
cellular response to oleic acid
cellular response to amine stimulus
cellular response to laminar fluid shear stress
cellular response to dexamethasone stimulus
negative regulation of leukocyte cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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