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Product Details
PA5-120685
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-412 of human ASS1 (NP_446464.1).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.13 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2914257
Product Specific Information
Positive test controls include: LO2, HeLa, Mouse heart, Mouse kidney, Rat kidney.
Target Information
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Argininosuccinate synthase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
Gene Aliases: AA408052; ASS; Ass-1; ASS1; ASSA; CTLN1; fold
UniProt ID: (Human) P00966, (Rat) P09034, (Mouse) P16460
Entrez Gene ID: (Human) 445, (Rat) 25698, (Mouse) 11898
Molecular Function:
ligase
urea cycle
citrulline metabolic process
argininosuccinate metabolic process
kidney development
liver development
arginine biosynthetic process
aspartate metabolic process
acute-phase response
midgut development
aging
response to nutrient
response to zinc ion
response to mycotoxin
response to estradiol
response to drug
positive regulation of nitric oxide biosynthetic process
response to growth hormone
diaphragm development
response to fatty acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to ammonium ion
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to glucagon stimulus
cellular response to oleic acid
cellular response to amine stimulus
cellular response to laminar fluid shear stress
cellular response to dexamethasone stimulus
negative regulation of leukocyte cell-cell adhesion
response to toxic substance
response to amine
response to lipopolysaccharide
response to amino acid
response to peptide hormone
response to steroid hormone
response to glucocorticoid
cellular amino acid biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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