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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ASZ1 Antibodies

          Invitrogen

          ASZ1 Polyclonal Antibody

          Advanced Verification
          View all (8) ASZ1 antibodies

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          Cite ASZ1 Polyclonal Antibody

          • Antibody Testing Data (4)
          • Advanced Verification (1)
          ASZ1 Antibody in Immunocytochemistry (ICC/IF)
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          ASZ1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          ASZ1 Antibody (PA5-54234) in ICC/IF

          Immunofluorecent analysis of ASZ1 in human cell line A-431 using ASZ1 Polyclonal Antibody (Product # PA5-54234). Staining shows localization to nucleoplasm and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ASZ1 Antibody in Immunocytochemistry (ICC/IF)
          ASZ1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ASZ1 Antibody in Immunohistochemistry (IHC)
          ASZ1 Antibody in Immunohistochemistry (IHC)
          ASZ1 Antibody
          ASZ1 Polyclonal Antibody

          Product Details

          PA5-54234

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ALP1. Recombinant protein control fragment (Product #RP-92763).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2637880

          Product Specific Information

          Immunogen sequence: DGHTQVVALL VAHGAEVNTQ DENGYTALTW AARQGHKNIV LKLLELGANK MLQTKDGKMP SEIAKRNKHH EIFNLLSFTL NPLEGKLQQL TKED

          Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

          Target Information

          Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; Ankyrin-like protein 1; ASZ1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

          View more View less

          Gene Aliases: ALP1; ANKL1; ASZ1; C7orf7; CT1.19; GASZ; Orf3

          View more View less

          UniProt ID: (Human) Q8WWH4

          View more View less

          Entrez Gene ID: (Human) 136991

          View more View less

          Function(s)
          signal transducer activity
          Process(es)
          male meiosis signal transduction multicellular organism development spermatogenesis cell differentiation gene silencing by RNA piRNA metabolic process DNA methylation involved in gamete generation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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