PA1-18297 detects ATG3 from human and rat samples.
PA1-18297 has been successfully used in immunohistochemistry, immunofluorescence, and Western blot procedures.
The PA1-18297 immunogen is a synthetic peptide corresponding to the N-terminal residues of human ATG3, conjugated to Blue Carrier Protein. The sequence is 100% conserved in mouse, rat, S. cerevisiae, Macaca mulatta (monkey) and canine.
Reconstitute with 100 µL of distilled water.
Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy (Tanida et al., 2002 [PubMed 11825910]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2610016C12Rik; APG3; APG3-like; APG3L; ATG3 autophagy related 3 homolog; autophagy-related 3; Autophagy-related protein 3; hApg3; Preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3
Gene Aliases: APG3; APG3-LIKE; APG3L; ATG3; PC3-96; PIG-1; Pig1
Molecular Function: ligase