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ATG4A Polyclonal Antibody
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FIGURE: 1 / 2
ATG4A Antibody (BS-3873R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with ATG4A Polyclonal Antibody, Unconjugated (bs-3873R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-3873R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ATG4A, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; Autophagin-2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A, cysteine peptidase; autophagy-related 4A; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; cysteine protease APG4A; Cysteine protease ATG4A; hAPG4A; HsAPG4A; MGC107179; unnamed protein product
Gene Aliases: AI627006; APG4A; ATG4A; Atg4al; AUTL2; AV169859; HsAPG4A
UniProt ID: (Human) Q8WYN0, (Mouse) Q8C9S8
Entrez Gene ID: (Human) 115201, (Mouse) 666468, (Rat) 678769
autophagosome assembly
mitophagy
proteolysis
lipid metabolic process
autophagy
protein transport
protein processing
piecemeal microautophagy of nucleus
aggrephagy
protein delipidation
mitophagy
C-terminal protein lipidation
protein targeting to membrane
cellular response to nitrogen starvation
nucleophagy
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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