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ATG7 Polyclonal Antibody
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Product Details
OSA00012G-500UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from c-terminal region of human ATG7 conjugated to blue carrier protein has been used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Amount
500 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: ATG7.
Target Information
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: APG7; APG7 autophagy 7-like; APG7-like; AT5G45900; ATAPG7; ATATG7; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; AUTOPHAGY 7; autophagy related 7 homolog; AUTOPHAGY-RELATED 7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; K15I22.10; K15I22_10; PEROXISOME UNUSUAL POSITIONING 4; PEUP4; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7; unnamed protein product
Gene Aliases: 1810013K23Rik; Agp7; APG7-LIKE; APG7L; ATG7; Atg7l; Gm21553; GSA7; SCAR31
UniProt ID: (Human) O95352, (Rat) Q641Y5, (Mouse) Q9D906
Entrez Gene ID: (Human) 10533, (Rat) 312647, (Mouse) 74244
autophagosome assembly
mitophagy
protein lipidation
autophagy
cellular response to nitrogen starvation
cellular response to starvation
positive regulation of catabolic process
protein transport
macroautophagy
positive regulation of protein modification process
response to nutrient levels
protein modification by small protein conjugation
cellular response to stress
piecemeal microautophagy of nucleus
regulation of circadian rhythm
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of protein catabolic process
rhythmic process
defense response to virus
regulation of macromolecule metabolic process
cellular response to hyperoxia
regulation of primary metabolic process
mitophagy
liver development
C-terminal protein lipidation
cellular amino acid metabolic process
organelle organization
mitochondrion organization
adult walking behavior
post-embryonic development
positive regulation of autophagy
positive regulation of macroautophagy
protein ubiquitination
cerebellar Purkinje cell layer development
pyramidal neuron development
central nervous system neuron axonogenesis
cerebral cortex development
protein catabolic process
neuron projection development
regulation of protein ubiquitination
negative stranded viral RNA replication
response to starvation
negative regulation of apoptotic process
late nucleophagy
neurological system process
cardiac muscle cell development
membrane organization
positive regulation of mucus secretion
regulation of mitophagy
negative regulation of histone H4-K16 acetylation
transport
suppression by virus of host autophagy
regulation of cell development
negative regulation of cell death
regulation of hemopoiesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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