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Invitrogen
ATG9A Polyclonal Antibody
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FIGURE: 1 / 7
ATG9A Antibody (PA5-85515) in ICC/IF
ATG9A Polyclonal Antibody detects ATG9A protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 100% MeOH for 5 min. Green: ATG9A protein stained by ATG9A Polyclonal Antibody (Product # PA5-85515) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-85515
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATG9A. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.98 mg/mL
Amount
98 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Pig (100%), Rhesus Monkey (100%), Bovine (100%).
Positive Control: 293T, A431, HeLa, RD.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apg9; APG9 autophagy 9-like 1; APG9-like 1; Apg911; APG9A; ATG 9A; ATG9 autophagy related 9 homolog A; autophagy 9-like 1 protein; autophagy protein 9; autophagy-related 9-like 1; autophagy-related 9A; Autophagy-related protein 9A; FLJ22169; mATG9; unnamed protein product
Gene Aliases: APG9L1; Atg9; ATG9A; Atg9l1; AU019532; mATG9; MGD3208; RGD1310450
UniProt ID: (Human) Q7Z3C6, (Mouse) Q68FE2, (Rat) Q5FWU3
Entrez Gene ID: (Human) 79065, (Mouse) 245860, (Rat) 363254
autophagosome assembly
mitophagy
transport
autophagy
protein transport
negative regulation of interferon-beta production
protein localization to Golgi apparatus
protein localization to pre-autophagosomal structure
piecemeal microautophagy of nucleus
late nucleophagy
innate immune response
mitophagy
lipid transport
negative regulation of macrophage cytokine production
phospholipid scrambling
bone morphogenesis
reticulophagy
programmed necrotic cell death
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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