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Product Details
PA5-117799
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human ATIC fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2902409
Target Information
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein ATIC; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Gene Aliases: AICAR; AICARFT; ATIC; HEL-S-70p; IMPCHASE; OK/SW-cl.86; PURH
UniProt ID: (Human) P31939
Entrez Gene ID: (Human) 471
brainstem development
nucleobase-containing compound metabolic process
'de novo' IMP biosynthetic process
nucleoside metabolic process
purine ribonucleoside monophosphate biosynthetic process
response to inorganic substance
cerebellum development
cerebral cortex development
organ regeneration
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
cell-cell adhesion
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