This target displays homology in the following species: Cow: 86%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 92%; Rat: 92%
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase class V type 10D; ATPase, class V, type 10D; P4-ATPase flippase complex alpha subunit ATP10D; Phospholipid-transporting ATPase VD; type IV aminophospholipid transporting ATPase
Gene Aliases: ATP10D; ATPVD; KIAA1487
UniProt ID: (Human) Q9P241
Entrez Gene ID: (Human) 57205
Molecular Function: primary active transporter