Search
Proteintech
ATP11B Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
13672-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ATP11B Fusion Protein Ag4654 (10-104 aa encoded by BC033880)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SSGSAWFAI ILMVVTCLFL DIIKKVFDRH LHPTSTEKAQ LTETNAGIKC LDSMCCFPEG EAACASVGRM LERVIGRCSP THISRCEISL SSLCCR (10-104 aa encoded by BC033880)
Target Information
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATPase Class VI type 11B; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; Phospholipid-transporting ATPase IF; probable phospholipid-transporting ATPase IF; TIEG; TIEG1; unnamed protein product
Gene Aliases: 1110019I14Rik; ATP11B; ATPIF; ATPIR; KIAA0956; mKIAA0956
UniProt ID: (Human) Q9Y2G3, (Mouse) Q6DFW5
Entrez Gene ID: (Human) 23200, (Rat) 361929, (Mouse) 76295
nucleotide binding
magnesium ion binding
protein binding
ATP binding
ion transmembrane transporter activity
ATPase activity
metal ion binding
phosphatidylserine-translocating ATPase activity
ATPase-coupled intramembrane lipid transporter activity
phospholipid-translocating ATPase activity
primary active transporter
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support