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Product Details
PA5-57578
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ATP11B
Conjugate
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2638349
Product Specific Information
Immunogen sequence: MKYQEINGRL VPEGPTPDSS EGNLSYLSSL SHLNNLSHLT TSSSFRTSPE NETELIKEHD LFFKAVSLCH TVQISNVQTD CTGDGPWQSN LAPSQLEY
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 80%.
Target Information
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase class VI type 11B; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; Phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Gene Aliases: ATP11B; ATPIF; ATPIR; KIAA0956
UniProt ID: (Human) Q9Y2G3
Entrez Gene ID: (Human) 23200
Molecular Function:
primary active transporter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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