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      ATP13A2 Polyclonal Antibody, Biotin

      See 7 other ATP13A2 antibodies ›
      ATP13A2 Polyclonal Antibody, Biotin conjugate for Western Blot and IHC

      Catalog#: PA5-22849 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-22849 100 µL
      375.00
      Please enter a quantity in the range of 1 to 199.
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      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human, Mouse
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen A synthetic peptide within the internal region of residues 200-300 of the human ATP13A2 protein.
      Conjugate Biotin
      Form Liquid
      Concentration 0.75 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer PBS
      Contains no preservative
      Storage Conditions 4° C, store in dark
      Tested Applications Dilution *
      Immunohistochemistry (IHC) 10-20 µg/ml
      Western Blot (WB) 2 µg/ml

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Product Specific Information

      Suggested positive control: human and mouse brain membrane prep lysate.

      Background/Target Information

      Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of these lysosomes and is formed most strongly in the brain, especially in the substantia nigra, a brain region which is known to play a central role in Parkinson's disease.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Bioinformatics

      Protein Aliases:

      ATPase type 13A2; Cation-transporting ATPase 13A2; HSA9947; KRPPD; PARK9; probable cation-transporting ATPase 13A2; putative ATPase; RP1-37C10.4

      Gene Aliases:

      1110012E06Rik; AA589443; ATP13A2; CLN12; HSA9947; KRPPD; PARK9

      UniProt ID:

      (Human) Q9NQ11, (Mouse) Q9CTG6

      Entrez Gene ID:

      (Human) 23400, (Mouse) 74772

      Molecular Function:

      cation transporter hydrolase ion channel transporter

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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