Immunogen sequence: SEFKPTYQDR VAPPGLTQIP QIQKTEISFR PNDPKSYEAY VLNIVRFLEK YKDSAQRDDM IFEDCGDVPS EPKERGDFNH ERGERKVCRF KLEWLGNCSG LNDETYGYKE GKPCIIIKLN RVLGFKPKPP KNESLETYPV MKYNPN
Na,K-ATPase is an integral membrane protein complex that hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+ found in most mammalian cells. The enzyme is comprised of an alpha and Beta subunit. The polypeptide has been shown to be the catalytically active subunit, whereas the Beta-polypeptide is glycosylated and appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. Na,K-ATPase Beta-1 subunit is expressed, exclusively, in epithelial cells.
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Protein Aliases: adenosinetriphosphatase; ATP1B; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; Na, K-ATPase beta-1 polypeptide; sodium pump subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic); sodium/potassium-dependent ATPase beta-1 subunit; Sodium/potassium-dependent ATPase subunit beta-1; sodium/potassium-transporting ATPase beta-1 chain; Sodium/potassium-transporting ATPase subunit beta-1
Gene Aliases: ATP1B; ATP1B1
UniProt ID: (Human) P05026
Entrez Gene ID: (Human) 481