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Proteintech
ATP1B2 Polyclonal Antibody
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Product Details
22338-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ATP1B2 Fusion Protein Ag17818 (64-171 aa encoded by BC126175)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Amount
51 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes the endogenous ATP1B2 protein in human brain. The bands between 45 kDa and 65 kDa represent the glycosylated forms of ATP1B2 in different levels.
Immunogen sequence: QTVSDHTPK YQDRLATPGL MIRPKTENLD VIVNVSDTES WDQHVQKLNK FLEPYNDSIQ AQKNDVCRPG RYYEQPDNGV LNYPKRACQF NRTQLGNCSG IGDSTHYGY (64-171 aa encoded by BC126175)
Target Information
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adhesion molecule in glia; adhesion molecule on glia; AMOG; ATPase, Na+/K+ transporting, beta 2 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 2; glial cell adhesion molecule; Na, K-ATPase beta-2 polypeptide; snoRNA MBI-85; Sodium Potassium ATPase; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic); sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2; unnamed protein product
Gene Aliases: AMOG; ATP1B2; Atpb-2; ATPB2; ATPB2S; RATATPB2S
UniProt ID: (Human) P14415, (Mouse) P14231
Entrez Gene ID: (Human) 482, (Rat) 24214, (Mouse) 11932
retina homeostasis
ion transport
potassium ion transport
sodium ion transport
cellular sodium ion homeostasis
cell adhesion
positive regulation of neuron projection development
lateral ventricle development
third ventricle development
neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration
cellular potassium ion homeostasis
cell-substrate adhesion
sodium ion export from cell
photoreceptor cell maintenance
protein stabilization
motor behavior
membrane repolarization
cell communication by electrical coupling involved in cardiac conduction
plasma membrane bounded cell projection organization
transport across blood-brain barrier
positive regulation of sodium ion export from cell
positive regulation of potassium ion import
negative regulation of glial cell migration
potassium ion import across plasma membrane
potassium ion import
positive regulation of ATPase activity
sodium ion transmembrane transport
positive regulation of potassium ion transmembrane transporter activity
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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