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Product Details
22338-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Immunocytochemistry (ICC/IF) |
- | View 2 publications 2 publications |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ATP1B2 Fusion Protein Ag17818 (64-171 aa encoded by BC126175) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.34 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
This antibody recognizes the endogenous ATP1B2 protein in human brain. The bands between 45 kDa and 65 kDa represent the glycosylated forms of ATP1B2 in different levels.
Immunogen sequence: QTVSDHTPK YQDRLATPGL MIRPKTENLD VIVNVSDTES WDQHVQKLNK FLEPYNDSIQ AQKNDVCRPG RYYEQPDNGV LNYPKRACQF NRTQLGNCSG IGDSTHYGY (64-171 aa encoded by BC126175)
Target Information
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adhesion molecule in glia; adhesion molecule on glia; AMOG; ATPase, Na+/K+ transporting, beta 2 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 2; glial cell adhesion molecule; Na, K-ATPase beta-2 polypeptide; snoRNA MBI-85; Sodium Potassium ATPase; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic); sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2
Gene Aliases: AMOG; ATP1B2; Atpb-2; ATPB2; ATPB2S; RATATPB2S
UniProt ID: (Human) P14415, (Mouse) P14231
Entrez Gene ID: (Human) 482, (Rat) 24214, (Mouse) 11932
Molecular Function:
primary active transporter
transport
cellular sodium ion homeostasis
cell adhesion
potassium ion import
establishment or maintenance of transmembrane electrochemical gradient
cellular potassium ion homeostasis
positive regulation of ATPase activity
ion transmembrane transport
sodium ion export from cell
protein stabilization
leukocyte migration
membrane repolarization
cell communication by electrical coupling involved in cardiac conduction
ATP hydrolysis coupled transmembrane transport
positive regulation of potassium ion transmembrane transporter activity
positive regulation of sodium ion export from cell
positive regulation of potassium ion import
regulation of cardiac conduction
potassium ion transport
sodium ion transmembrane transport
ion transport
sodium ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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