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Invitrogen
ATP1B2 Polyclonal Antibody
FIGURE: 1 / 12
ATP1B2 Antibody (PA5-26279) in IHC (P)
Immunohistochemistry analysis of ATP1B2 in formalin-fixed and paraffin-embedded human hepatocarcinoma. Samples were incubated with ATP1B2 polyclonal antibody (Product # PA5-26279) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-26279
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 115-141 amino acids from the central region of human ATP1B2
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2543779
Product Specific Information
This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology.
Target Information
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adhesion molecule in glia; adhesion molecule on glia; AMOG; ATPase, Na+/K+ transporting, beta 2 polypeptide; Na, K-ATPase beta-2 polypeptide; Sodium Potassium ATPase; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic); sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2
Gene Aliases: AMOG; ATP1B2
UniProt ID: (Human) P14415
Entrez Gene ID: (Human) 482
transport
cellular sodium ion homeostasis
cell adhesion
potassium ion import
establishment or maintenance of transmembrane electrochemical gradient
cellular potassium ion homeostasis
positive regulation of ATPase activity
ion transmembrane transport
sodium ion export from cell
protein stabilization
leukocyte migration
membrane repolarization
cell communication by electrical coupling involved in cardiac conduction
ATP hydrolysis coupled transmembrane transport
positive regulation of potassium ion transmembrane transporter activity
positive regulation of sodium ion export from cell
positive regulation of potassium ion import
regulation of cardiac conduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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