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Invitrogen
ATP4B Polyclonal Antibody
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FIGURE: 1 / 6
ATP4B Antibody (PA5-83771) in IHC (P)
Immunohistochemistry analysis of ATP4B in human gastrointestinal, kidney, liver and stomach. Samples were incubated with ATP4B polyclonal antibody (Product # PA5-83771). Shows similar protein distribution across tissues to independent ATP4B antibody (Product # PA5-84118) (B).
Product Details
PA5-83771
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ATP4B. Recombinant protein control fragment (Product #RP-99966).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TPDYQDQLRS PGVTLRPDVY GEKGLEIVYN VSDNRTWADL TQTLHAFLAG YSPAAQEDSI NCTSEQYFFQ ESFRAPNHTK FSCKFTADML
Highest antigen sequence indentity to the following orthologs: Mouse - 83%, Rat - 80%.
Target Information
The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase H+/K+ transporting beta subunit; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; Gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; H+/K+ ATPase beta; potassium-transporting ATPase beta chain; Potassium-transporting ATPase subunit beta; Proton pump beta chain
Gene Aliases: ATP4B; ATP6B
UniProt ID: (Human) P51164
Entrez Gene ID: (Human) 496
ion transport
potassium ion transport
sodium ion transport
cellular sodium ion homeostasis
cell adhesion
cellular potassium ion homeostasis
response to lipopolysaccharide
sodium ion export from cell
pH reduction
potassium ion transmembrane transport
hydrogen ion transmembrane transport
potassium ion import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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