The Drosophila gene for the ATP synthase epsilon subunit (ATP5E) is known as stunted or sun (Kidd et al. 2005). Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c).
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Protein Aliases: ATP synthase epsilon chain, mitochondrial; ATP synthase F1 subunit epsilon; ATP synthase subunit epsilon, mitochondrial; ATPase subunit epsilon; F(0)F(1)-ATPase; H(+)-transporting two-sector ATPase; mitochondrial ATP synthase epsilon chain; mitochondrial ATPase
Gene Aliases: 2410043G19Rik; ATP5E; ATP5F1E; ATPE; AV000645; MC5DN3