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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:5,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
ELISA (ELISA) |
Assay-dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant Human V-type proton ATPase subunit C 2 protein (190-262AA) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
5 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.03% Proclin 300 |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2867894 |
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, V1 subunit C, isoform 2; V-ATPase C2 subunit; V-ATPase subunit C 2; V-type ATPase C2 subunit a isoform; V-type proton ATPase subunit C 2; vacuolar H+ ATPase C2; Vacuolar proton pump subunit C 2
Gene Aliases: 1110038G14Rik; ATP6C2; ATP6V1C2; VMA5
UniProt ID: (Human) Q8NEY4, (Mouse) Q99L60, (Rat) Q6AYE4
Entrez Gene ID: (Human) 245973, (Mouse) 68775, (Rat) 362802
Molecular Function:
ATP synthase
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