|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Recombinant fragment, corresponding to amino acids 1407-1500 of Human ATP7A.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1500-1:2500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20840 detects ATP7A in human, mouse and rat samples.
PA1-20840 has been successfully used in Western blot procedures.
The PA1-20840 immunogen is a recombinant fragment, corresponding to amino acids 1407-1500 of Human ATP7A..
Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.