Product References
Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.
Life science alliance
Kim JY,Atanassov I,Dethloff F,Kroczek L,Langer T
Fri Sep 01 00:00:00 EDT 2023
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Signal transduction and targeted therapy
Ma B,Ju A,Zhang S,An Q,Xu S,Liu J,Yu L,Fu Y,Luo Y
Fri Jun 16 00:00:00 EDT 2023
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Life (Basel, Switzerland)
Cafournet C,Zanin S,Guimier A,Hully M,Assouline Z,Barcia G,de Lonlay P,Steffann J,Munnich A,Bonnefont JP,Rötig A,Ruzzenente B,Metodiev MD
Sat Feb 04 00:00:00 EST 2023
Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function.
eLife
Huang M,Coral D,Ardalani H,Spegel P,Saadat A,Claussnitzer M,Mulder H,Franks PW,Kalamajski S
Mon Mar 06 00:00:00 EST 2023
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
bioRxiv : the preprint server for biology
Xu WQ,Cheah JS,Xu C,Messing J,Freibaum BD,Boeynaems S,Taylor JP,Udeshi ND,Carr SA,Ting AY
Wed Feb 08 00:00:00 EST 2023
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Nucleic acids research
Jia Z,Meng F,Chen H,Zhu G,Li X,He Y,Zhang L,He X,Zhan H,Chen M,Ji Y,Wang M,Guan MX
Fri Sep 09 00:00:00 EDT 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
The Journal of cell biology
Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M
Mon Jun 07 00:00:00 EDT 2021
Mechanistic insights into mitochondrial tRNAAla 3'-end metabolism deficiency.
The Journal of biological chemistry
Ji Y,Nie Z,Meng F,Hu C,Chen H,Jin L,Chen M,Zhang M,Zhang J,Liang M,Wang M,Guan MX
Thu Jul 01 00:00:00 EDT 2021
Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.
Nucleic acids research
Zhang Q,He X,Yao S,Lin T,Zhang L,Chen D,Chen C,Yang Q,Li F,Zhu YM,Guan MX
Fri May 07 00:00:00 EDT 2021
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
The Journal of biological chemistry
Jin X,Zhang Z,Nie Z,Wang C,Meng F,Yi Q,Chen M,Sun J,Zou J,Jiang P,Guan MX
Mon Aug 02 00:00:00 EDT 2021
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Nucleic acids research
Meng F,Zhou M,Xiao Y,Mao X,Zheng J,Lin J,Lin T,Ye Z,Cang X,Fu Y,Wang M,Guan MX
Mon Jan 25 00:00:00 EST 2021
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Cellular and molecular gastroenterology and hepatology
Sun D,Niu Z,Zheng HX,Wu F,Jiang L,Han TQ,Wei Y,Wang J,Jin L
Mon Mar 07 00:00:00 EST 2022
Tissue-specific expression atlas of murine mitochondrial tRNAs.
The Journal of biological chemistry
He Q,He X,Xiao Y,Zhao Q,Ye Z,Cui L,Chen Y,Guan MX
Sun Aug 01 00:00:00 EDT 2021
ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.
Frontiers in cell and developmental biology
Yang Y,Li C,Gu X,Zhen J,Zhu S,Lv T,Wan Q,Liu Y
Fri Aug 27 00:00:00 EDT 2021
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
Nature cell biology
Zhang LS,Xiong QP,Peña Perez S,Liu C,Wei J,Le C,Zhang L,Harada BT,Dai Q,Feng X,Hao Z,Wang Y,Dong X,Hu L,Wang ED,Pan T,Klungland A,Liu RJ,He C
Thu Jul 01 00:00:00 EDT 2021
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Carcinogenesis
Zhuang X,Chen Y,Wu Z,Xu Q,Chen M,Shao M,Cao X,Zhou Y,Xie M,Shi Y,Zeng Y,Bu H
Tue Jul 14 00:00:00 EDT 2020
SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
iScience
Ma Y,Zhu S,Lv T,Gu X,Feng H,Zhen J,Xin W,Wan Q
Fri Aug 21 00:00:00 EDT 2020
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNAHis mutation.
The Journal of biological chemistry
Gong S,Wang X,Meng F,Cui L,Yi Q,Zhao Q,Cang X,Cai Z,Mo JQ,Liang Y,Guan MX
Fri Jan 24 00:00:00 EST 2020
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Nucleic acids research
Jia Z,Zhang Y,Li Q,Ye Z,Liu Y,Fu C,Cang X,Wang M,Guan MX
Thu Feb 28 00:00:00 EST 2019
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Nucleic acids research
Jia Z,Zhang Y,Li Q,Ye Z,Liu Y,Fu C,Cang X,Wang M,Guan MX
Thu Feb 28 00:00:00 EST 2019
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Human molecular genetics
Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Wed May 01 00:00:00 EDT 2019
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Human molecular genetics
Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Wed May 01 00:00:00 EDT 2019
A deafness-associated mitochondrial DNA mutation altered the tRNASer(UCN) metabolism and mitochondrial function.
Mitochondrion
Xue L,Chen Y,Tang X,Yao J,Huang H,Wang M,Ye S,Wang M,Guan MX
Wed May 01 00:00:00 EDT 2019
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Nucleic acids research
Zhao X,Cui L,Xiao Y,Mao Q,Aishanjiang M,Kong W,Liu Y,Chen H,Hong F,Jia Z,Wang M,Jiang P,Guan MX
Mon Nov 04 00:00:00 EST 2019
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
Human mutation
Ruzzenente B,Assouline Z,Barcia G,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Sat Dec 01 00:00:00 EST 2018
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
Human mutation
Ruzzenente B,Assouline Z,Barcia G,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD
Sat Dec 01 00:00:00 EST 2018
Contribution of the tRNAIle 4317A→G mutation to the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA 1555A→G mutation.
The Journal of biological chemistry
Meng F,He Z,Tang X,Zheng J,Jin X,Zhu Y,Ren X,Zhou M,Wang M,Gong S,Mo JQ,Shu Q,Guan MX
Fri Mar 02 00:00:00 EST 2018
Contribution of the tRNAIle 4317A→G mutation to the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA 1555A→G mutation.
The Journal of biological chemistry
Meng F,He Z,Tang X,Zheng J,Jin X,Zhu Y,Ren X,Zhou M,Wang M,Gong S,Mo JQ,Shu Q,Guan MX
Fri Mar 02 00:00:00 EST 2018
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Cell death & disease
Aulas A,Lyons SM,Fay MM,Anderson P,Ivanov P
Tue Nov 13 00:00:00 EST 2018
A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function.
The Journal of biological chemistry
Zhou M,Xue L,Chen Y,Li H,He Q,Wang B,Meng F,Wang M,Guan MX
Fri Jan 26 00:00:00 EST 2018
A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function.
The Journal of biological chemistry
Zhou M,Xue L,Chen Y,Li H,He Q,Wang B,Meng F,Wang M,Guan MX
Fri Jan 26 00:00:00 EST 2018
A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNALeu(UUR).
The Journal of biological chemistry
Zhou M,Wang M,Xue L,Lin Z,He Q,Shi W,Chen Y,Jin X,Li H,Jiang P,Guan MX
Fri Aug 25 00:00:00 EDT 2017
A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNALeu(UUR).
The Journal of biological chemistry
Zhou M,Wang M,Xue L,Lin Z,He Q,Shi W,Chen Y,Jin X,Li H,Jiang P,Guan MX
Fri Aug 25 00:00:00 EDT 2017
