The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: aminophospholipid translocase; ATPase 8A1, aminophospholipid transporter (APLT), class I; ATPase 8A1, p type; ATPase class I type 8A member 1; ATPase II; ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; Chromaffin granule ATPase II; P4-ATPase flippase complex alpha subunit ATP8A1; Phospholipid-transporting ATPase IA; probable phospholipid-transporting ATPase IA
Gene Aliases: AI481521; AI853962; APLT; Atp3a2; ATP8A1; ATPASEII; Atpc1; ATPIA; ATPP2; AW743152; AW822227; B230107D19Rik; ClassI