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|Tested species reactivity||Hamster, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The carboxy-terminal portion of human ATR protein (amino acids 2122-2644).|
|Storage buffer||whole serum|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23182 detects ATR in human, mouse and hamster samples.
PA1-23182 has been successfully used in Western Blot procedures.
PA1-23182 immunogen corresponds to The carboxy-terminal portion of human ATR protein (amino acids 2122-2644).
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ataxia telangiectasia and Rad3-related protein; FRAP-related protein-1; FRP1; MEC1; MEC1, mitosis entry checkpoint 1, homolog; SCKL; SCKL1; serine/threonine-protein kinase ATR
ATR; FCTCS; FRP1; I79_000761; MEC1; SCKL; SCKL1