It is not recommended to aliquot this antibody.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ataxia telangiectasia and Rad3 related; Ataxia telangiectasia and Rad3-related protein; ATR serine/threonine kinase; FRAP-related protein 1; FRAP-related protein-1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; Rad3 related protein; Serine/threonine-protein kinase ATR
Gene Aliases: ATR; FCTCS; FRP1; I79_000761; MEC1; SCKL; SCKL1
UniProt ID: (Human) Q13535