Keep as concentrated solution.
Positive Control: 293T, A431, HeLa, HepG2, Raji, Raji NE, Raji nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ataxia telangiectasia and Rad3 related antibody; Ataxia telangiectasia and Rad3-related protein; ataxia telangiectasia and Rad3-related protein antibody; ATR antibody; FRAP-related protein 1; FRAP-related protein 1 antibody; FRAP-related protein-1; FRAP-related protein-1 antibody; FRP1 antibody; homolog antibody; MEC1; MEC1 antibody; MEC1, mitosis entry checkpoint 1, homolog; mitosis entry checkpoint 1; protein kinase ATR antibody; Rad3 related protein antibody; SCKL antibody; SCKL1 antibody; Serine/threonine-protein kinase ATR; serine/threonine-protein kinase ATR antibody
Gene Aliases: ATR; FCTCS; FRP1; MEC1; SCKL; SCKL1
UniProt ID: (Human) Q13535