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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from a sequence between amino acids 500-550 of the human ATRIP protein (aka TREX1) [Gene ID 11277].|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||3-8 µg/mg of lysate|
|Western Blot (WB)||1:5000-1:15,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: Hela whole cell extract, antigen standard for ATRIP (transient overexpression lysate).
ATRIP is an 86 kDa protein that is phosphorylated by ATR, regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. It localizes to the intranuclear foci after DNA damage or inhibition of replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3' Repair Exonuclease 1; ATM and Rad3-related-interacting protein; ATR interacting protein; ATRIP; Deoxyribonuclease III; DRN3; FLJ12343; Three Prime Repair Exonuclease 1; TREX1