PA1-519 detects human and mouse ATRIP.\r
PA1-519 has been successfully used in Western blot, immunoprecipitation and immunofluorescence procedures. By Western blot, this antibody detects an ~ 86 kDa protein from human HeLa cells.\r
PA1-519 antigen corresponds to amino acids 1-182 of human ATRIP
ATRIP is an 86 kDa protein that is phosphorylated by ATR, regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. It localizes to the intranuclear foci after DNA damage or inhibition of replication.
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Protein Aliases: ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR IP; ATR-interacting protein; DRN3; FLJ12343
Gene Aliases: 6620401K05Rik; AGS1; ATRIP