Immunogen sequence: AHSFNKAPSAT SPSGQLPHHS STQPLDLAPG RMPIYYQMSR LPAGYTLHET PPAGASPVLT PQESQS
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 84%.
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ataxin 1-like; Ataxin-1-like; ATXN1L; BOAT; BOAT1; Brother of ataxin-1; Brother of ATXN1
Gene Aliases: ATXN1L; BOAT; BOAT1
UniProt ID: (Human) P0C7T5
Entrez Gene ID: (Human) 342371