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AVP Antibody (PA5-25471) in ICC/IF
Immunocytochemistry analysis of AVP in ZR-75-1 cells. Samples were incubated in AVP polyclonal antibody (Product # PA5-25471) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Product Details
PA5-25471
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 102-129 amino acids of human AVP
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542971
Target Information
This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antidiuretic hormone; AVP-NPII; copeptin; neurohypophyseal; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; Vasopressin; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin
Gene Aliases: ADH; ARVP; AVP; AVP-NPII; AVRP; VP
UniProt ID: (Human) P01185
Entrez Gene ID: (Human) 551
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
renal water homeostasis
generation of precursor metabolites and energy
water transport
apoptotic process
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of female receptivity
grooming behavior
locomotory behavior
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of cell growth
positive regulation of cAMP biosynthetic process
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
positive regulation of peptidyl-serine phosphorylation
response to testosterone
response to nicotine
social behavior
regulation of renal sodium excretion
vasoconstriction
hyperosmotic salinity response
maternal behavior
negative regulation of apoptotic process
penile erection
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
sodium-independent organic anion transport
response to ethanol
positive regulation of vasoconstriction
negative regulation of transmission of nerve impulse
ERK1 and ERK2 cascade
protein kinase C signaling
negative regulation of release of cytochrome c from mitochondria
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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