|Immunohistochemistry (Paraffin) (IHC (P))||2 - 7 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from C-terminus of human AVPR1B.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset (89%) Bovine (84%).
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antidiuretic hormone receptor 1b; arginine vasopressin receptor 3; AVPR V1b; AVPR V3; AVPR1B; AVPR3; pituitary vasopressin receptor 3; V1b receptor; V1b vasopressin receptor; V1bR; Vasopressin V1b receptor; Vasopressin V3 receptor; VPR3
Gene Aliases: AVPR1B; AVPR3; VPR3
UniProt ID: (Human) P47901
Entrez Gene ID: (Human) 553
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